Pulmicort 500mcg/ml Respule

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Manufacturer AstraZeneca
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Dr. Mohd Izzat Amir Bin Awang
Reviewed byDr. Mohd Izzat Amir Bin AwangDoctor of Medicine (MD), University of Mansoura - Manchester
Dr. Adeline Carol Peters
Written byDr. Adeline Carol PetersBachelor of Medicine and Bachelor of Surgery (MBBS) — Manipal Academy of Higher Education (MAHE)

Last updated:

Overview

Pulmicort 500mcg/ml Respule is a prescription-only medicine (POM) presented as a medicine, with Budesonide 500mcg/mL (0.5mg/mL) as its active ingredient content.

This page is limited to product, safety and handling information, in line with Malaysian rules on prescription medicine information for the public. Your prescriber or pharmacist is the right source for anything beyond that, together with the leaflet inside the pack.

Through DoctorOnCall, this product is supplied after an online consultation with a licensed doctor and a valid prescription, and it is checked by a registered pharmacist before dispensing. Take it exactly as prescribed, and speak to your doctor before stopping, changing the dose, or starting any other medicine alongside it.

Directions for Use

Shake the respule gently, then open and empty its full contents into the nebuliser chamber of a suitable jet nebuliser (not an ultrasonic nebuliser, which can inactivate budesonide); it should not be mixed with other medicines in the same nebule unless your doctor or pharmacist has specifically advised this. Breathe the mist in through a mouthpiece or well-fitted face mask as instructed, and rinse the mouth (and wash the face if a mask was used) with water afterwards to reduce the risk of oral thrush and skin irritation.

Dosage

The dose of Pulmicort 500mcg/ml Respule is individualised by your doctor based on age, asthma severity, and response to treatment, and is usually given once or twice daily via a jet nebuliser. Your doctor will advise the correct dose, frequency, and how to adjust it during periods of worsened symptoms – do not change the dose on your own.

Storage Instructions

Store below 30°C in a dry place, away from direct sunlight and out of reach of children.

Side Effects

  • Headache
  • Nausea or upset stomach
  • Throat irritation (with inhaled forms)
  • Cough or hoarseness
  • White patches in the mouth (oral thrush)
  • Increased risk of infections
  • Dizziness
  • Acne or skin thinning (with prolonged use)

Contraindications

  • Known hypersensitivity to budesonide or any ingredient in this product
  • Active, untreated respiratory tract infections such as tuberculosis or fungal/viral lung infections, unless specifically directed by a doctor

Drug / Food Interactions

  • Ketoconazole, itraconazole, ritonavir, and other strong CYP3A4 inhibitors can significantly increase systemic budesonide exposure
  • Other corticosteroids (oral, injected, or inhaled) taken together may increase the total steroid load and side-effect risk
  • Grapefruit juice may modestly increase budesonide absorption

Quick Tips

  • Rinse your mouth with water (and spit it out) after every nebulisation to prevent oral thrush
  • Wash and dry the face if a mask is used, to reduce skin irritation
  • Use only with a jet nebuliser, not an ultrasonic device, unless advised otherwise
  • Continue regular use even when asthma is well controlled – this medicine is for prevention, not for relieving a sudden attack
  • Keep a fast-acting reliever inhaler available for sudden breathing difficulty, as advised by your doctor
  • Clean the nebuliser equipment as instructed to prevent contamination

Ingredients / Active Ingredients

  • Budesonide 500mcg/mL (0.5mg/mL)

Safety Advice

Pregnancy

Use With Care

This medicine should be used cautiously during pregnancy. Monitoring may be required.

Breastfeeding

Use With Care

Use with caution. Monitor infant for potential adverse reactions.

Kidney

Use With Care

Use cautiously. Dose adjustment or monitoring may be required.

Liver

Use With Care

Use cautiously. Liver function monitoring may be required.

Alcohol

Use With Care

Caution is advised when consuming alcohol with this medicine.

Driving

Generally Safe

This medicine is generally safe and should not impair your driving ability.

Frequently Asked Questions

Product Specifications

BrandAstraZeneca
ManufacturerAstraZeneca
ClassificationPrescription medicine
Ingredients / Active IngredientsBudesonide
Pack Size5s
Shelf LifeUse this product before the expiry date stated on the packaging. Do not use the medicine if the expiry date has passed.

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