Remedica Pizogran 0.5mg Tablet

Manufacturer Remedica
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Dr. Mohd Izzat Amir Bin Awang
Reviewed byDr. Mohd Izzat Amir Bin AwangDoctor of Medicine (MD), University of Mansoura - Manchester
Dr. Adeline Carol Peters
Written byDr. Adeline Carol PetersBachelor of Medicine and Bachelor of Surgery (MBBS) — Manipal Academy of Higher Education (MAHE)

Last updated:

Overview

Remedica Pizogran 0.5mg Tablet contains Pizotifen (as pizotifen hydrogen malate) 0.5mg and is presented as a tablet. It is supplied in pack sizes of 100s and 10s.

It is classified as a non-prescription medicine, so no prescription is needed to order it. Under Malaysian rules for medicine information, this page carries product, safety and handling information only.

You can consult a doctor or pharmacist online on DoctorOnCall about this product before or after you order. Every order is checked by a registered pharmacist before it is delivered. Always read the label and the leaflet supplied with the pack.

Directions for Use

Remedica Pizogran 0.5mg Tablet should be taken exactly as prescribed by your doctor following an online consultation with DoctorOnCall. It is usually taken once daily at night, as this can help reduce daytime drowsiness, or in divided doses as directed. The tablet can be swallowed with water, with or without food, and should not be stopped or have its dose changed without first speaking to your doctor.

Dosage

The dose of Remedica Pizogran 0.5mg Tablet is individualised by the prescribing doctor, typically starting at a low dose such as 0.5mg at night and gradually increased over one to two weeks based on response and tolerability, up to a maintenance dose commonly in the range of 1.5mg daily. Your doctor will confirm the exact dose and schedule appropriate for your condition; do not adjust the dose yourself.

Shelf Life

Remedica Pizogran 0.5mg Tablet typically has a shelf life of around 36 months from the date of manufacture when stored unopened under the recommended conditions. Always check the expiry date printed on the blister strip and outer carton, and do not use the tablets beyond this date.

Storage Instructions

Store Remedica Pizogran 0.5mg Tablet below 30°C in a cool, dry place away from direct sunlight and moisture, in its original packaging until ready for use. Keep out of the reach and sight of children, and do not store in a bathroom cabinet exposed to steam or in a hot car.

Side Effects

  • Drowsiness or fatigue
  • Increased appetite and weight gain
  • Dry mouth
  • Dizziness
  • Nausea or upset stomach
  • Constipation

Contraindications

  • Known hypersensitivity to pizotifen or any other ingredient in the tablet
  • Angle-closure glaucoma
  • Urinary retention or significant difficulty passing urine, such as in some cases of enlarged prostate
  • Use with caution in the elderly, who may be more sensitive to sedative and anticholinergic effects

Drug / Food Interactions

  • Alcohol and other sedating medicines (sleeping tablets, some antihistamines, anxiolytics) can intensify the drowsiness caused by pizotifen
  • Monoamine oxidase inhibitors (MAOIs) should generally be avoided or used only under close medical supervision
  • Other medicines with anticholinergic effects may add to dry mouth, blurred vision, or urinary retention
  • Inform your doctor of all other medicines and supplements you are taking before starting treatment

Quick Tips

  • Take your dose at night as advised to reduce the impact of daytime drowsiness
  • Avoid driving or operating machinery until you know how this medicine affects you
  • Monitor your weight periodically, as increased appetite is a common effect during treatment
  • Keep all follow-up appointments with your doctor so your migraine prophylaxis can be reviewed
  • Never share this prescription medicine with another person

Ingredients / Active Ingredients

  • Pizotifen (as pizotifen hydrogen malate) 0.5mg
  • Lactose
  • Microcrystalline cellulose
  • Other standard tablet excipients

Safety Advice

Pregnancy

Safe If Prescribed

This medicine should only be used during pregnancy if prescribed by a doctor after careful evaluation.

Breastfeeding

Limited Data

Limited data on excretion in breast milk. Consult a doctor before use.

Kidney

Use With Care

Use cautiously. Dose adjustment or monitoring may be required.

Liver

Use With Care

Use cautiously. Liver function monitoring may be required.

Alcohol

Not Advisable

It is not advisable to consume alcohol while taking this medicine.

Driving

Use With Care

Use caution while driving until you know how this medicine affects you.

Relevant Information

Remedica Pizogran 0.5mg Tablet is used specifically to prevent migraine attacks over time rather than to treat a migraine that has already started; a fast-acting painkiller or migraine-specific treatment may still be needed for breakthrough attacks, as advised by your doctor. Because pizotifen can cause sedation and increased appetite, your doctor will periodically review whether continued treatment remains appropriate and may adjust the dose based on how well your migraines are controlled.

Frequently Asked Questions

Product Specifications

BrandRemedica
ManufacturerRemedica
ClassificationNon-prescription
Ingredients / Active IngredientsPizotifen
Pack Size100s, 10s

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Important Medical Information

💊 Recommended Dosage:

The dose of Remedica Pizogran 0.5mg Tablet is individualised by the prescribing doctor, typically starting at a low dose such as 0.5mg at night and gradually increased over one to two weeks based on response and tolerability, up to a maintenance dose commonly in the range of 1.5mg daily. Your doctor will confirm the exact dose and schedule appropriate for your condition; do not adjust the dose yourself.

🛑 Contraindications (Do not use if):
  • Known hypersensitivity to pizotifen or any other ingredient in the tablet
  • Angle-closure glaucoma
  • Urinary retention or significant difficulty passing urine, such as in some cases of enlarged prostate
  • Use with caution in the elderly, who may be more sensitive to sedative and anticholinergic effects
If you are unsure, please chat with us or consult your doctor.
⚠️ Common Side Effects:
  • Drowsiness or fatigue
  • Increased appetite and weight gain
  • Dry mouth
  • Dizziness
  • Nausea or upset stomach
  • Constipation
Stop taking this medication immediately and consult your doctor if you experience severe allergic reactions or side effects.
IMPORTANT: Unsure? Chat with our pharmacists (Mon - Sat, 9:00am - 6:00pm) before buying.