Requip 0.25mg Tablet
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Prescription Required
Overview
Requip 0.25mg Tablet contains ropinirole 0.25mg in an immediate-release formulation, a non-ergot dopamine agonist used to treat Parkinson’s disease and restless legs syndrome (RLS). Unlike the once-daily prolonged-release form, this tablet is generally taken multiple times a day for Parkinson’s disease, or as a single dose before bedtime for RLS.
Ropinirole works by directly stimulating dopamine D2/D3 receptors in the brain, mimicking dopamine’s natural effects. In Parkinson’s disease this improves motor symptoms, while in restless legs syndrome it reduces the uncomfortable urge to move the legs, particularly in the evening and at night.
How it Works
Ropinirole is a non-ergot dopamine agonist that selectively binds to and activates D2 and D3 dopamine receptors. In Parkinson’s disease this compensates for reduced dopamine production in the brain’s striatum, improving movement control. In restless legs syndrome, dopaminergic activity is thought to modulate the sensory-motor pathways responsible for the urge to move the legs.
Directions for Use
Take Requip 0.25mg Tablet with food to help reduce nausea. For Parkinson’s disease, take each dose at the times advised by your doctor throughout the day; for restless legs syndrome, take your dose 1-3 hours before you go to bed. Swallow the tablet whole with water.
Dosage
For Parkinson’s disease, Requip 0.25mg Tablet is usually started at a low dose taken several times a day and increased gradually according to your doctor’s individualised titration schedule. For restless legs syndrome, it is generally taken as a single dose 1-3 hours before bedtime, starting low and adjusted as needed. Your doctor will confirm the schedule that applies to your condition.
Shelf Life
Use this product before the expiry date stated on the packaging. Do not use the medicine if the expiry date has passed.
Storage Instructions
Store below 30°C in a dry place, away from direct sunlight and out of reach of children.
Side Effects
- Dizziness or light-headedness
- Nausea or vomiting
- Fatigue or drowsiness
- Headache
- Sleepiness or sudden sleep onset
- Dry mouth
- Constipation
- Swelling in the legs or arms
- Unusual urges (e.g., gambling, shopping)
Contraindications
- Known hypersensitivity to ropinirole or any ingredient in this product
- Severe kidney impairment without appropriate dose adjustment
- Use with caution in pregnancy and breastfeeding, only if clearly assessed as necessary by your doctor
Drug / Food Interactions
- Antipsychotic medicines that block dopamine receptors may reduce the effectiveness of ropinirole
- CYP1A2 inhibitors such as ciprofloxacin and fluvoxamine can raise ropinirole blood levels
- Oestrogen-containing medicines (e.g. hormone replacement therapy) can increase ropinirole levels
- Cigarette smoking can lower ropinirole blood levels, so your doctor may need to adjust the dose if you start or stop smoking
Quick Tips
- Take with food if you experience nausea
- Rise slowly from sitting or lying down to reduce dizziness
- Avoid driving or operating machinery if you feel drowsy or experience sudden sleepiness
- This immediate-release form is not directly interchangeable with the once-daily prolonged-release (PD/XL) form – follow your doctor’s specific prescription
- Tell your doctor promptly about any new urges such as gambling, shopping, or other compulsive behaviours
Frequently Asked Questions
What is Requip 0.25mg Tablet used for?
Requip 0.25mg Tablet is used to treat Parkinson’s disease and restless legs syndrome (RLS), two different conditions in which ropinirole is dosed differently depending on which one your doctor is treating.
How is dosing different for Parkinson’s disease compared with restless legs syndrome?
For Parkinson’s disease, ropinirole is usually taken multiple times throughout the day. For restless legs syndrome, it is generally taken as a single dose 1-3 hours before bedtime, since RLS symptoms are typically worse in the evening and night.
Can I switch between this tablet and the once-daily prolonged-release form on my own?
No, the immediate-release and prolonged-release (PD/XL) forms are not directly interchangeable. Any switch between formulations should only be done under your doctor’s guidance.
Why does my doctor ask about gambling or shopping habits during follow-up?
Dopamine agonists such as ropinirole can rarely cause new compulsive behaviours like gambling, shopping, or hypersexuality. Your doctor checks for this so the dose can be adjusted if needed.
What should I do if I miss a dose of Requip 0.25mg Tablet?
Take the missed dose as soon as you remember, unless it is almost time for your next dose – in that case, skip the missed dose and continue your regular schedule. Do not take a double dose.
Can I buy Requip 0.25mg Tablet from DoctorOnCall?
Yes, Requip 0.25mg Tablet is available through DoctorOnCall, a licensed online pharmacy serving our Malaysian and Singaporean customers. As this is a prescription medicine, you will need to complete an online consultation so a doctor can assess your suitability and issue a valid prescription before the order is processed. This ensures the medicine is appropriate for your condition and used under proper medical supervision, whether you are ordering from Malaysia or Singapore.
Is the medication provided by DoctorOnCall genuine and safe to use?
DoctorOnCall sources its medicines through appropriate licensed pharmacy supply channels for our Malaysian and Singaporean customers. All orders are dispensed and checked by a registered pharmacist before delivery. Always use Requip 0.25mg Tablet according to your doctor’s instructions and the information provided with the product.
What payment methods does DoctorOnCall accept?
We accept payment via Online Banking, Credit Card, and e-Wallets (Boost, GrabPay) for our Malaysian and Singaporean customers, so you can choose whichever method is most convenient for you at checkout.
Does DoctorOnCall provide an installment payment plan for Requip 0.25mg Tablet?
DoctorOnCall provides an installment payment plan for eligible Malaysian and Singaporean customers, where applicable. Available plans, eligibility, and terms can vary by market, so please contact DoctorOnCall Customer Service for the latest information on installment options for your order.
Is delivery free, and how much does shipping for Requip 0.25mg Tablet cost?
Delivery charges may vary for our Malaysian and Singaporean customers depending on your delivery location and the applicable order terms at the time of purchase. For the most accurate and up-to-date delivery fee information, please contact DoctorOnCall Customer Service before placing your order.
How long does delivery take for Requip 0.25mg Tablet?
Our Malaysian customers can generally expect delivery within 3-5 working days, while our Singaporean customers generally receive their orders within 5-7 working days. These are expected timeframes rather than guarantees, and actual delivery time may vary depending on your delivery location, order processing time, courier operations, and whether the order falls on a weekend or public holiday.
What is DoctorOnCall’s shipping, return, or cancellation policy for Requip 0.25mg Tablet?
Shipping, return, and cancellation terms may vary for our Malaysian and Singaporean customers depending on the product and your order details. Please refer to DoctorOnCall’s Shipping & Delivery Policy and Return, Refund & Exchange Policy, or contact Customer Service, for the specific terms that apply to your order.
Ingredients / Active Ingredients
- Ropinirole 0.25mg (as ropinirole hydrochloride)
Safety Advice
Pregnancy
This medicine should be used cautiously during pregnancy. Monitoring may be required.
Breastfeeding
This medicine is generally safe during breastfeeding with minimal risk to the infant.
Kidney
Use cautiously. Dose adjustment or monitoring may be required.
Liver
Use cautiously. Liver function monitoring may be required.
Alcohol
It is not advisable to consume alcohol while taking this medicine.
Driving
It is not advisable to drive if you experience side effects from this medicine.
Medical Review
