Retafyllin 200mg Tablet
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Prescription Required
Overview
Retafyllin 200mg Tablet contains theophylline 200mg, a methylxanthine bronchodilator used in the long-term maintenance treatment of asthma and chronic obstructive pulmonary disease (COPD), including chronic bronchitis and emphysema. It has a narrow therapeutic index, meaning blood levels must be monitored to keep the dose effective and safe.
Theophylline works by relaxing the smooth muscle around the airways and reducing airway inflammation, which widens the airways and eases breathing. It also has a mild stimulant effect on the diaphragm, which can help respiratory muscle function in some patients.
How it Works
Theophylline is a methylxanthine that inhibits phosphodiesterase enzymes, increasing levels of cyclic AMP in airway smooth muscle, and also blocks adenosine receptors that would otherwise promote airway narrowing. Together these actions relax the bronchial smooth muscle, reduce airway inflammation, and improve diaphragmatic contractility.
Directions for Use
Take Retafyllin 200mg Tablet at consistent times each day, generally with a consistent relationship to meals as advised by your doctor, since food can affect absorption of some formulations. If your tablet is a sustained- or prolonged-release formulation, swallow it whole with water – do not crush, chew, or split it, as this can alter how the dose is released.
Dosage
The dose of Retafyllin 200mg Tablet is individualised for each patient based on body weight, smoking status, and periodic blood theophylline level monitoring, because the effective dose is close to the dose that can cause toxicity. Your doctor will determine your starting dose, adjust it based on blood test results, and set the monitoring schedule that is right for you.
Shelf Life
Use this product before the expiry date stated on the packaging. Do not use the medicine if the expiry date has passed.
Storage Instructions
Store below 30°C in a dry place, away from direct sunlight and out of reach of children.
Side Effects
- Nausea or upset stomach
- Headache or dizziness
- Trouble sleeping (insomnia)
- Increased heart rate
- Irritability or restlessness
- Muscle cramps or twitching
Contraindications
- Known hypersensitivity to theophylline or other xanthine derivatives
- Uncontrolled cardiac arrhythmias
- Active peptic ulcer disease
- Uncontrolled seizure disorders
Drug / Food Interactions
- Cigarette smoking speeds up theophylline elimination and can lower blood levels – dose changes may be needed if you start or stop smoking
- Certain antibiotics (e.g. ciprofloxacin, erythromycin, clarithromycin) can raise theophylline blood levels and increase toxicity risk
- Cimetidine and some antifungal medicines can also raise theophylline levels
- Phenytoin, carbamazepine, and rifampicin can lower theophylline levels, reducing its effectiveness
- High caffeine intake may add to stimulant-type side effects such as palpitations and insomnia
Quick Tips
- Attend all scheduled blood tests to check your theophylline level
- Tell your doctor immediately if you start or stop smoking, as your dose may need adjusting
- Report symptoms such as persistent nausea, tremor, or a fast/irregular heartbeat promptly
- Do not take extra doses even if you feel your symptoms are not controlled – consult your doctor instead
- Keep a consistent daily routine for taking this medicine, including its timing with meals
Frequently Asked Questions
What is Retafyllin 200mg Tablet used for?
Retafyllin 200mg Tablet is used for the long-term maintenance treatment of asthma and chronic obstructive pulmonary disease (COPD), helping to widen the airways and reduce bronchospasm.
Why do I need regular blood tests while taking this medicine?
Theophylline has a narrow therapeutic index, meaning the difference between an effective dose and a dose that can cause side effects is small. Blood level monitoring helps your doctor keep your dose in the safe and effective range.
Does smoking affect how this medicine works?
Yes, smoking speeds up how quickly your body clears theophylline, which can lower blood levels and reduce effectiveness. If you smoke or plan to stop smoking, tell your doctor so your dose can be reviewed.
Can I drink coffee or tea while taking this medicine?
You should limit caffeine intake, as caffeine is chemically related to theophylline and combining the two may increase side effects such as palpitations, jitteriness, or difficulty sleeping.
What should I do if I miss a dose of Retafyllin 200mg Tablet?
Take the missed dose as soon as you remember, unless it is almost time for your next dose – in that case, skip the missed dose and continue your regular schedule. Do not double the dose, as this can increase the risk of toxicity.
Can I buy Retafyllin 200mg Tablet from DoctorOnCall?
Yes, Retafyllin 200mg Tablet is available through DoctorOnCall, a licensed online pharmacy serving our Malaysian and Singaporean customers. As this is a prescription medicine, you will need to complete an online consultation so a doctor can assess your suitability and issue a valid prescription before the order is processed. This ensures the medicine is appropriate for your condition and used under proper medical supervision, whether you are ordering from Malaysia or Singapore.
Is the medication provided by DoctorOnCall genuine and safe to use?
DoctorOnCall sources its medicines through appropriate licensed pharmacy supply channels for our Malaysian and Singaporean customers. All orders are dispensed and checked by a registered pharmacist before delivery. Always use Retafyllin 200mg Tablet according to your doctor’s instructions and the information provided with the product.
What payment methods does DoctorOnCall accept?
We accept payment via Online Banking, Credit Card, and e-Wallets (Boost, GrabPay) for our Malaysian and Singaporean customers, so you can choose whichever method is most convenient for you at checkout.
Does DoctorOnCall provide an installment payment plan for Retafyllin 200mg Tablet?
DoctorOnCall provides an installment payment plan for eligible Malaysian and Singaporean customers, where applicable. Available plans, eligibility, and terms can vary by market, so please contact DoctorOnCall Customer Service for the latest information on installment options for your order.
Is delivery free, and how much does shipping for Retafyllin 200mg Tablet cost?
Delivery charges may vary for our Malaysian and Singaporean customers depending on your delivery location and the applicable order terms at the time of purchase. For the most accurate and up-to-date delivery fee information, please contact DoctorOnCall Customer Service before placing your order.
How long does delivery take for Retafyllin 200mg Tablet?
Our Malaysian customers can generally expect delivery within 3-5 working days, while our Singaporean customers generally receive their orders within 5-7 working days. These are expected timeframes rather than guarantees, and actual delivery time may vary depending on your delivery location, order processing time, courier operations, and whether the order falls on a weekend or public holiday.
What is DoctorOnCall’s shipping, return, or cancellation policy for Retafyllin 200mg Tablet?
Shipping, return, and cancellation terms may vary for our Malaysian and Singaporean customers depending on the product and your order details. Please refer to DoctorOnCall’s Shipping & Delivery Policy and Return, Refund & Exchange Policy, or contact Customer Service, for the specific terms that apply to your order.
Ingredients / Active Ingredients
- Theophylline 200mg
Safety Advice
Pregnancy
Limited information is available regarding use during pregnancy. Use only if clearly needed.
Breastfeeding
Generally not recommended while breastfeeding.
Kidney
Generally safe, but caution may be required in some patients.
Liver
Use cautiously. Liver function monitoring may be required.
Alcohol
Caution is advised when consuming alcohol with this medicine.
Driving
Use caution while driving until you know how this medicine affects you.
Medical Review
