Revatio 20mg Tablet
Rx- FDA Approved
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Prescription Required
Overview
Revatio 20mg Tablet contains sildenafil 20mg, a phosphodiesterase type 5 (PDE5) inhibitor used specifically for the treatment of pulmonary arterial hypertension (PAH) – high blood pressure in the arteries of the lungs – to improve exercise capacity and slow clinical worsening of the condition. This is a distinct indication and dosing schedule from sildenafil products used for erectile dysfunction.
Sildenafil works by inhibiting the PDE5 enzyme in the blood vessels of the lungs, which increases levels of a signalling molecule called cGMP. This relaxes and widens the pulmonary arteries, lowering the pressure the right side of the heart must work against to pump blood through the lungs.
How it Works
In PAH, the small arteries of the lungs are abnormally narrowed and stiff. Sildenafil blocks PDE5, an enzyme that breaks down cGMP in the smooth muscle of the pulmonary blood vessels. Higher cGMP levels cause these vessels to relax and dilate, reducing pulmonary vascular resistance and easing the workload on the right ventricle of the heart.
Directions for Use
Take Revatio 20mg Tablet three times a day at evenly spaced intervals, with or without food, to maintain a steady level of medicine in your body. Swallow the tablet whole with water, and try to take each dose at the same three times every day rather than only when needed.
Dosage
The usual dose of Revatio 20mg Tablet for PAH is 20mg taken three times daily, roughly 4-6 hours apart, which is a different regimen from the on-demand dosing used for erectile dysfunction. Your doctor will confirm the correct dose and schedule for your condition and monitor your response over time.
Shelf Life
Use this product before the expiry date stated on the packaging. Do not use the medicine if the expiry date has passed.
Storage Instructions
Store below 30°C in a dry place, away from direct sunlight and out of reach of children.
Side Effects
- Headache
- Flushing (warmth or redness of the face)
- Dizziness
- Upset stomach or indigestion
- Nasal congestion
- Vision changes (blurred vision or sensitivity to light)
- Back pain or muscle aches
- Nausea
Contraindications
- Known hypersensitivity to sildenafil or any ingredient in this product
- Concomitant use with any form of nitrate medicine (e.g. glyceryl trinitrate) due to the risk of severe, life-threatening low blood pressure
- Concomitant use with riociguat, a soluble guanylate cyclase stimulator also used for pulmonary hypertension
- Severe liver impairment or recent stroke/heart attack, unless specifically assessed by your doctor
Drug / Food Interactions
- Nitrates and riociguat must never be combined with sildenafil due to dangerous blood pressure drops
- Alpha-blockers (e.g. for prostate enlargement) may increase the risk of low blood pressure when combined
- Strong CYP3A4 inhibitors (e.g. ritonavir, ketoconazole, itraconazole) can raise sildenafil blood levels significantly
- Grapefruit juice may increase sildenafil levels and should be used cautiously
Quick Tips
- Take all three daily doses at evenly spaced times, not just when symptoms are noticed
- Never take this medicine together with nitrate medicines or riociguat
- Attend follow-up appointments to track your exercise capacity and PAH progression
- Report any sudden change in vision or hearing to your doctor immediately
- Do not adjust your dose or stop treatment without your doctor’s advice
Frequently Asked Questions
What is Revatio 20mg Tablet used for?
Revatio 20mg Tablet is used specifically to treat pulmonary arterial hypertension (PAH), a condition of high blood pressure in the lung arteries, to improve your ability to exercise and to help slow the progression of the disease.
Is this the same as sildenafil used for erectile dysfunction?
It contains the same active ingredient, sildenafil, but this product is formulated and dosed specifically for PAH – taken three times daily on a fixed schedule rather than on an as-needed basis – and should only be used for the condition your doctor has prescribed it for.
How will I know if this medicine is working for my PAH?
Your doctor will assess your response using measures such as a walking distance test, symptom review, and sometimes heart function tests, and may adjust your treatment plan, including adding other PAH therapies, based on these results.
Can I take this medicine with other PAH treatments?
Yes, sildenafil for PAH is often combined with other classes of PAH medicine as part of your overall treatment plan, but your doctor must confirm which combinations are safe, as nitrates and riociguat must never be combined with sildenafil.
What should I do if I miss a dose of Revatio 20mg Tablet?
Take the missed dose as soon as you remember, unless it is almost time for your next scheduled dose – in that case, skip the missed dose and continue your regular three-times-daily schedule. Do not take a double dose.
Can I buy Revatio 20mg Tablet from DoctorOnCall?
Yes, Revatio 20mg Tablet is available through DoctorOnCall, a licensed online pharmacy serving our Malaysian and Singaporean customers. As this is a prescription medicine, you will need to complete an online consultation so a doctor can assess your suitability and issue a valid prescription before the order is processed. This ensures the medicine is appropriate for your condition and used under proper medical supervision, whether you are ordering from Malaysia or Singapore.
Is the medication provided by DoctorOnCall genuine and safe to use?
DoctorOnCall sources its medicines through appropriate licensed pharmacy supply channels for our Malaysian and Singaporean customers. All orders are dispensed and checked by a registered pharmacist before delivery. Always use Revatio 20mg Tablet according to your doctor’s instructions and the information provided with the product.
What payment methods does DoctorOnCall accept?
We accept payment via Online Banking, Credit Card, and e-Wallets (Boost, GrabPay) for our Malaysian and Singaporean customers, so you can choose whichever method is most convenient for you at checkout.
Does DoctorOnCall provide an installment payment plan for Revatio 20mg Tablet?
DoctorOnCall provides an installment payment plan for eligible Malaysian and Singaporean customers, where applicable. Available plans, eligibility, and terms can vary by market, so please contact DoctorOnCall Customer Service for the latest information on installment options for your order.
Is delivery free, and how much does shipping for Revatio 20mg Tablet cost?
Delivery charges may vary for our Malaysian and Singaporean customers depending on your delivery location and the applicable order terms at the time of purchase. For the most accurate and up-to-date delivery fee information, please contact DoctorOnCall Customer Service before placing your order.
How long does delivery take for Revatio 20mg Tablet?
Our Malaysian customers can generally expect delivery within 3-5 working days, while our Singaporean customers generally receive their orders within 5-7 working days. These are expected timeframes rather than guarantees, and actual delivery time may vary depending on your delivery location, order processing time, courier operations, and whether the order falls on a weekend or public holiday.
What is DoctorOnCall’s shipping, return, or cancellation policy for Revatio 20mg Tablet?
Shipping, return, and cancellation terms may vary for our Malaysian and Singaporean customers depending on the product and your order details. Please refer to DoctorOnCall’s Shipping & Delivery Policy and Return, Refund & Exchange Policy, or contact Customer Service, for the specific terms that apply to your order.
Ingredients / Active Ingredients
- Sildenafil 20mg (as sildenafil citrate)
Safety Advice
Pregnancy
Use during pregnancy is generally not recommended unless absolutely necessary.
Breastfeeding
Generally not recommended while breastfeeding.
Kidney
Use cautiously. Dose adjustment or monitoring may be required.
Liver
Use cautiously. Liver function monitoring may be required.
Alcohol
Caution is advised when consuming alcohol with this medicine.
Driving
Use caution while driving until you know how this medicine affects you.
Medical Review
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