Rohto C Cube Eye Drop

Brand Rohto
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Dr. Mohd Izzat Amir Bin Awang
Reviewed byDr. Mohd Izzat Amir Bin AwangDoctor of Medicine (MD), University of Mansoura - Manchester
Dr. Adeline Carol Peters
Written byDr. Adeline Carol PetersBachelor of Medicine and Bachelor of Surgery (MBBS) — Manipal Academy of Higher Education (MAHE)

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Overview

Rohto C Cube Eye Drop is a multi-ingredient over-the-counter eye drop from Rohto, the Japanese eye-care brand distributed by Mentholatum, formulated as a clear aqueous ophthalmic solution supplied in a compact 8ml bottle with the brand’s signature precision-tip dropper. It is sold as a personal-care eye drop rather than a prescription-only ophthalmic medicine, and is intended for direct application to the surface of the eye.

Each application delivers a combination of Vitamin B6 (Pyridoxine Hydrochloride), Sodium Chondroitin Sulfate, and Potassium L-Aspartate, together with a small amount of menthol that gives the drop its characteristic cool, refreshing sensation on instillation. The formulation is completed with purified water and pH-adjusting agents to keep the solution close to the eye’s natural pH and comfortable to use.

Rohto C Cube is part of the wider Rohto eye drop range sold in Malaysia and Singapore, distinguished within that range by its particular blend of a vitamin, an amino acid, and a lubricating polysaccharide alongside the cooling menthol note that Rohto drops are known for. It is sold as a single 8ml bottle intended for regular personal use rather than single-dose or hospital-format packaging, and like other over-the-counter eye drops, it is formulated for topical ocular application only.

Directions for Use

Before use, wash your hands thoroughly. If you wear contact lenses, remove them first, as Rohto C Cube Eye Drop should not be applied while lenses are in place.

Tilt your head back or lie down, gently pull down the lower eyelid to form a small pocket, and hold the bottle close to the eye without letting the dropper tip touch the eye, eyelid, lashes, or any other surface. Instil 1 to 2 drops into the pocket, then close your eyes gently for a few moments and press lightly on the inner corner of the eye near the nose to limit the drop draining into the tear duct.

Wipe away any excess solution around the eye with a clean tissue, and replace the cap securely after use. If you wear contact lenses, wait at least 15 minutes after application before reinserting them.

Dosage

Rohto C Cube Eye Drop is intended for topical use in the eye(s) only. Unless the product label or a pharmacist advises otherwise, the usual application is 1 to 2 drops into the affected eye or eyes, applied as needed up to around 5 to 6 times a day, spacing applications evenly through the day rather than instilling drops in quick succession.

Do not exceed the frequency stated on the packaging. If you use other eye drops or ointments at the same time, leave a gap of at least 5 to 10 minutes between different products so each one has time to be absorbed. This product is intended for adults and children old enough to tolerate eye drop application as directed on the label; for younger children, check the packaging or ask a pharmacist before use.

Shelf Life

Use Rohto C Cube Eye Drop before the expiry date printed on the bottle and carton. Once opened, the solution should not be kept indefinitely — check the packaging for the manufacturer’s stated in-use discard period and dispose of the bottle once that period has passed, even if some solution remains, since an opened eye drop can no longer be guaranteed sterile beyond that point.

Storage Instructions

Store Rohto C Cube Eye Drop below 30°C (room temperature), away from direct sunlight, heat, and moisture, and keep the cap tightly closed between uses to protect the solution from contamination. Keep the bottle out of reach and sight of children. Do not use the product if the solution appears discoloured, cloudy, or contains particles, or if the tamper-evident seal has been broken before first use.

Side Effects

  • Common: A brief stinging or cooling sensation immediately after the drop is instilled, which usually fades within seconds to a minute.
  • Common: Mild, temporary redness or irritation of the eye following application.
  • Common: Watery eyes or slightly blurred vision for a short time right after use.
  • Serious: Signs of an allergic reaction such as significant eyelid swelling, severe itching, hives, or a rash around the eyes, which needs urgent medical attention as it may indicate hypersensitivity to one of the ingredients.
  • Serious: Persistent eye pain, worsening redness, changes in vision, or sensitivity to light that does not settle after stopping use, which should be assessed by a doctor or eye care professional promptly, as these are not expected effects of the product.

Contraindications

  • Known hypersensitivity or allergy to Vitamin B6 (Pyridoxine Hydrochloride), Sodium Chondroitin Sulfate, Potassium L-Aspartate, menthol, or any other ingredient in the formulation.
  • Active eye infection, eye injury, or recent eye surgery, unless a doctor or pharmacist has confirmed the product is appropriate to use.
  • Use while wearing soft or hard contact lenses — lenses should be removed before application and only reinserted after the recommended waiting period.
  • The bottle should not be used if the solution has changed colour, become cloudy, or if the tamper-evident seal was already broken at first use.

Drug / Food Interactions

  • Rohto C Cube Eye Drop is applied topically to the eye and is not known to interact with orally taken medicines or with food, as it is not intended to be swallowed and has minimal systemic absorption when used as directed.
  • If more than one eye drop or eye ointment is used at the same time, apply them at least 5 to 10 minutes apart so that one product does not wash out another before it has been absorbed.
  • Inform your pharmacist or doctor about all eye drops and eye medicines you are currently using, including other over-the-counter products, before starting Rohto C Cube Eye Drop.

Quick Tips

  • Always check that the tamper-evident seal is intact before first use and that the solution is clear, not cloudy or discoloured.
  • Keep the dropper tip from touching your eye, fingers, or any surface to avoid contaminating the remaining solution in the bottle.
  • If you use more than one type of eye drop, apply them several minutes apart rather than back-to-back.
  • Store the bottle upright, tightly capped, and away from heat or direct sunlight, and keep it out of children’s reach.
  • Note the date you open a new bottle so you know when to discard it according to the manufacturer’s in-use period on the carton.
  • Carry a spare tissue when using the drops away from home to blot any excess solution around the eye.

Ingredients / Active Ingredients

Active ingredients include Vitamin B6 (Pyridoxine Hydrochloride), Sodium Chondroitin Sulfate, and Potassium L-Aspartate. Other ingredients may include menthol for a cooling sensation, purified water, and pH adjusters.

Relevant Information

Precautions: Rohto C Cube Eye Drop is for external use in the eye only and must never be swallowed or injected. Remove contact lenses before application and wait at least 15 minutes before reinserting them. Use with care in young children, and check with a pharmacist before use in infants or if you are pregnant or breastfeeding, since eye drop use in these groups should be guided by professional advice. Stop use and reassess if irritation, unusual discomfort, or vision changes occur, and avoid using the product beyond the printed expiry date or stated in-use discard period after opening.

When to See a Doctor or Pharmacist: Speak to a doctor or pharmacist before using Rohto C Cube Eye Drop if you have an existing eye condition, have recently had eye surgery, or are already using a prescribed eye medication. Seek prompt medical attention if you experience significant eye pain, swelling, discharge, marked redness, vision changes, or signs of an allergic reaction after using the product, or if mild irritation does not settle within a short time of use.

Frequently Asked Questions

Product Specifications

BrandRohto
ClassificationNon-prescription
Volume8ml

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