Saizen Liquid 12mg (8mg/ml) Pre-filled Pen

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Dr. Mohd Izzat Amir Bin Awang
Reviewed byDr. Mohd Izzat Amir Bin AwangDoctor of Medicine (MD), University of Mansoura - Manchester
Dr. Adeline Carol Peters
Written byDr. Adeline Carol PetersBachelor of Medicine and Bachelor of Surgery (MBBS) — Manipal Academy of Higher Education (MAHE)

Last updated:

Overview

Saizen Liquid 12mg (8mg/ml) Pre-filled Pen contains Somatropin 12mg (8mg/ml) per injection pen and is available as a medicine. It is classified as a prescription medicine and may only be obtained with a valid prescription from a registered medical practitioner.

Only product, safety and handling information is published here. Anything beyond that is explained to you directly by your doctor or pharmacist as part of your consultation.

DoctorOnCall is a licensed online pharmacy. Orders for Saizen Liquid 12mg (8mg/ml) Pre-filled Pen are processed only after a doctor has assessed your suitability and issued a prescription, and every order is checked by a registered pharmacist before it is sent out.

Directions for Use

Inject Saizen Liquid 12mg (8mg/ml) Pre-filled Pen subcutaneously (under the skin), usually once daily in the evening, exactly as taught by your specialist care team, rotating injection sites between the abdomen, thigh, or buttock to reduce skin reactions. Your care team will personally train you or your caregiver on correct pen use, dose setting, and needle disposal before any injections are given at home.

Dosage

The dose of Saizen Liquid 12mg (8mg/ml) Pre-filled Pen is highly individualised by your paediatric endocrinologist or growth hormone specialist, based on body weight or body surface area, growth response, and regular IGF-1 blood level monitoring. Never start, stop, or change your dose without explicit instruction from your specialist care team, as both under-treatment and over-treatment carry risks.

Storage Instructions

Store in a refrigerator (2-8°C). Do not freeze. Once in use, it may be stored as per the product-specific in-use period at either refrigerated or room temperature according to the pen’s instructions – do not freeze it at any point, and keep it away from direct light and out of reach of children.

Side Effects

  • Redness, itching, or swelling at the injection site
  • Headache
  • Joint pain or stiffness
  • Mild swelling of the hands, feet, or ankles (fluid retention)
  • Serious: severe or worsening headache with vision changes, nausea, or vomiting may indicate raised pressure inside the skull (intracranial hypertension) – contact your care team immediately if these occur

Contraindications

  • Known hypersensitivity to somatropin or any ingredient in this product
  • Evidence of active malignancy (growth hormone should not be started until tumour treatment is complete and the specialist confirms it is safe)
  • Critical illness following major surgery, multiple accidental trauma, or acute respiratory failure
  • Closed bone growth plates, when used for growth promotion in children
  • Active proliferative or severe non-proliferative diabetic retinopathy

Drug / Food Interactions

  • Oral corticosteroids may blunt the growth-promoting effect and require dose adjustment by the specialist
  • Insulin or oral diabetes medicines may need dose adjustment, as somatropin can raise blood sugar levels
  • Oestrogen therapy (including oral contraceptives) may reduce somatropin’s effect, requiring specialist dose review
  • Thyroid hormone levels should be monitored, as somatropin treatment may unmask or worsen underlying hypothyroidism

Quick Tips

  • Attend every scheduled appointment with your paediatric endocrinologist or growth hormone specialist without exception
  • Keep to the exact injection schedule and technique your specialist care team taught you
  • Never adjust the dose yourself, even if growth or symptoms seem slower or faster than expected
  • Contact your care team immediately for severe headache, vision changes, new lumps, or unexplained swelling

Ingredients / Active Ingredients

  • Somatropin 12mg (8mg/ml) per injection pen

Frequently Asked Questions

Product Specifications

ClassificationPrescription medicine
Pack Contents1.50ml x1 (pen)
Shelf LifeUse this product before the expiry date stated on the packaging. Do not use the medicine if the expiry date has passed.

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