Sitavio-M 50/850mg Tablet

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Dr. Mohd Izzat Amir Bin Awang
Reviewed byDr. Mohd Izzat Amir Bin AwangDoctor of Medicine (MD), University of Mansoura - Manchester
Dr. Adeline Carol Peters
Written byDr. Adeline Carol PetersBachelor of Medicine and Bachelor of Surgery (MBBS) — Manipal Academy of Higher Education (MAHE)

Last updated:

Overview

Sitavio-M 50/850mg Tablet contains Sitagliptin 50mg (as sitagliptin phosphate monohydrate) and Metformin hydrochloride 850mg and is available as a tablet. It is classified as a prescription medicine and may only be obtained with a valid prescription from a registered medical practitioner.

Only product, safety and handling information is published here. Anything beyond that is explained to you directly by your doctor or pharmacist as part of your consultation.

DoctorOnCall is a licensed online pharmacy. Orders for Sitavio-M 50/850mg Tablet are processed only after a doctor has assessed your suitability and issued a prescription, and every order is checked by a registered pharmacist before it is sent out.

Directions for Use

Sitavio-M tablets should be swallowed whole with a glass of water, taken with meals (for example, with breakfast and dinner) to help reduce stomach upset. Do not crush or chew the tablet. If a dose is missed, take it with the next meal as usual; do not double the dose to make up for a missed one. Patients should continue to follow their prescribed diet and exercise plan alongside this medicine.

Dosage

The usual dose of Sitavio-M 50/850mg is one tablet taken twice daily with meals, to reduce the gastrointestinal side effects associated with metformin. The specific strength prescribed depends on the patient’s current metformin dose and blood glucose control, as assessed by the doctor. Patients should never adjust their own dose or switch between Sitavio-M strengths without medical advice, particularly as metformin dosing may need to be reduced in patients with impaired kidney function.

Storage Instructions

Store below 30°C in a dry place, away from direct sunlight and out of reach of children.

Side Effects

  • Nausea or vomiting
  • Diarrhea
  • Headache
  • Low blood sugar (especially when taken with other diabetes medications)
  • Upper respiratory tract infection
  • Stomach discomfort
  • Fatigue

Contraindications

  • Known hypersensitivity to sitagliptin, metformin, or any component of the formulation
  • Severe kidney impairment
  • Acute or chronic metabolic acidosis, including diabetic ketoacidosis
  • Conditions that increase the risk of lactic acidosis, such as severe dehydration, severe infection, or shock
  • Significant liver impairment

Drug / Food Interactions

  • Alcohol can increase the risk of lactic acidosis associated with metformin and should be avoided or limited
  • Iodinated contrast media used in certain imaging procedures may require metformin to be temporarily stopped – inform your doctor if you are scheduled for a scan involving contrast dye
  • Combining with sulfonylureas or insulin may increase the risk of hypoglycaemia
  • Certain diuretics, corticosteroids, and other medicines that affect blood glucose or kidney function may require dose review – always inform your doctor of all medicines you are taking

Quick Tips

  • Take each dose with a meal to reduce stomach upset
  • Attend scheduled blood tests, as your doctor may periodically check kidney function while you are on this medicine
  • Inform your doctor before any procedure involving contrast dye or if you become seriously unwell, as metformin may need to be temporarily paused
  • Seek urgent medical attention if you experience unusual muscle pain, difficulty breathing, or severe tiredness, which can rarely signal lactic acidosis

Ingredients / Active Ingredients

  • Sitagliptin 50mg (as sitagliptin phosphate monohydrate)
  • Metformin hydrochloride 850mg

Safety Advice

Pregnancy

Use With Care

This medicine should be used cautiously during pregnancy. Monitoring may be required.

Breastfeeding

Limited Data

Limited data on excretion in breast milk. Consult a doctor before use.

Kidney

Not Advisable

Not generally recommended in patients with kidney disease.

Liver

Use With Care

Use cautiously. Liver function monitoring may be required.

Alcohol

Use With Care

Caution is advised when consuming alcohol with this medicine.

Driving

Use With Care

Use caution while driving until you know how this medicine affects you.

Frequently Asked Questions

Product Specifications

BrandNovugen Pharma
ManufacturerNovugen Pharma
ClassificationPrescription medicine
Ingredients / Active IngredientsMetformin + Sitagliptin
Pack Size60s
Shelf LifeUse this product before the expiry date stated on the packaging. Do not use the medicine if the expiry date has passed.

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