Skinoren (Azelaic Acid) 20% Cream

Topical cream containing azelaic acid 20%, dispensed by a registered pharmacist.

Brand LEO
Manufacturer LEO
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  • FDA Approved
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Dr. Mohd Izzat Amir Bin Awang
Reviewed byDr. Mohd Izzat Amir Bin AwangDoctor of Medicine (MD), University of Mansoura - Manchester
Dr. Adeline Carol Peters
Written byDr. Adeline Carol PetersBachelor of Medicine and Bachelor of Surgery (MBBS) — Manipal Academy of Higher Education (MAHE)

Last updated:

Key Information

What is Skinoren 20% Cream?

What is Skinoren 20% Cream?

  • Skinoren 20% Cream contains azelaic acid 20% and is supplied in a 30g tube.
  • It belongs to a class of medicines known as dicarboxylic acids.
  • It is a non-prescription product, dispensed by a registered pharmacist.
  • Read the pack and leaflet before use, and use it only as directed on the label or as advised by your pharmacist.
Is this strength right for me?

Is this strength right for me?

  • Skinoren is available as a 20% cream only. Check the pack and leaflet for the directions for use.
  • Apply a thin layer to clean, dry skin, as directed on the pack. Follow the frequency stated on the label or advised by your pharmacist.
  • Do not use more than directed, and do not use it for longer than advised.
  • It should be used with caution if you are pregnant or breastfeeding. Not sure whether it suits you? Ask our pharmacist before ordering.
Delivery, packaging and ordering

Delivery, packaging and ordering

  • Choose your product and place your order. No prescription is needed, and your order is dispensed by a registered pharmacist.
  • You can consult a doctor or pharmacist online on DoctorOnCall about this product before or after you order.
  • The product page lists fast delivery. Check the page for current delivery options and charges.
  • Check the product packaging for its Malaysian registration details, and verify them through the relevant Ministry of Health Malaysia resources.
Side effects, safety and when to seek help

Side effects, safety and when to seek help

  • There are a few possible side effects with azelaic acid, although not everyone will experience them. Common effects of this type of product include mild burning, stinging, itching or redness where it is applied.
  • Do not use it if you are allergic to azelaic acid, propylene glycol, or any other ingredient in the cream.
  • It is for topical use, and generally has no significant food or drug interactions when applied externally. Tell your pharmacist about any other skin products you use. Avoid contact with your eyes, mouth and broken skin.
  • Stop using it and ask your pharmacist or doctor if you develop severe irritation, swelling, blistering, or signs of infection. Seek immediate medical attention for swelling of the face or lips, difficulty breathing, or any severe or unexpected reaction.

How to use your Skinoren 20% Cream

  1. Step 1

    Read the pack and leaflet, and check with your pharmacist if you are unsure whether Skinoren suits you. Tell them about any allergies (including to propylene glycol), skin conditions, whether you are pregnant or breastfeeding, and any other skin products you use.

  2. Step 2

    Wash the area gently and dry it completely before applying.

  3. Step 3

    Gently apply a thin layer to the affected area of clean, dry skin, as directed on the label or by your pharmacist. Rub it in lightly, avoid your eyes, mouth, nostrils and broken skin, and wash your hands afterwards.

  4. Step 4

    Use it only as directed, and do not apply more than advised. Stop and ask your pharmacist or doctor if irritation is severe or does not settle.

Delivery & Returns

  • Malaysia-wide delivery
  • No prescription needed
  • Licensed pharmacy
  • Doctor consultation

If your order arrives damaged

  • Do not use Skinoren 20% Cream if the packaging is damaged, the tube is leaking or torn, or the seal appears to have been tampered with.
  • Check the tube and carton carefully before use.
  • Contact us on WhatsApp immediately and provide photos of the outer packaging and the tube.
  • We’ll review the issue and arrange a replacement at no extra cost if the delivery issue is verified.

Returns policy

For safety reasons, Skinoren 20% Cream cannot be returned or exchanged once it has left our pharmacy, except in cases involving a verified delivery issue, such as damaged packaging, an incorrect item or a missing item.

If there is a problem with your order, contact us within 24 hours of delivery so we can review the issue and advise you on the next steps.

Chat with us on WhatsApp

Dosage

A small, pea-sized amount is generally enough to cover the whole face; using more does not improve results and may increase irritation. Some people are advised to start with once-daily application in the first week and build up to twice daily as tolerated, and treatment is usually continued for several months to achieve and maintain results.

Shelf Life

Unopened, Skinoren 20% Cream is generally stable until the expiry date printed on the packaging. Once opened, it is best used within the period stated on the carton (commonly several months) as the product’s stability and effectiveness can reduce over time after opening.

Storage Instructions

Do

  • Store below 30°C in a dry place, away from direct sunlight.
  • Keep the cap tightly closed after each use.
  • Keep out of reach of children.
  • Check the expiry date printed on the tube before use.

Don't

  • Don’t leave it in a hot car, bathroom or near a stove.
  • Don’t use it after the expiry date.
  • Don’t share your tube with others.
  • Don’t use it if the cream changes colour or texture, or the tube is damaged.

Side Effects

Skinoren 20% Cream may cause local skin reactions, particularly during the early weeks of treatment. These reactions are often mild, but their severity and duration can vary between individuals. Monitor your skin and seek medical advice if symptoms become severe or persistent.

Burning, Stinging or Tingling

A burning, stinging or tingling sensation may occur after application, particularly during the first few weeks.

Skin Redness

The treated area may appear red or look more irritated than usual.

Dryness and Peeling

The skin may become dry, flaky or start to peel in the treated area.

Itching

Itching may develop at the application site and can occur alongside other local skin reactions.

Mild Skin Irritation

Mild irritation may be more noticeable early in treatment and may lessen as the skin adjusts. If it persists or worsens, seek medical advice.

Rare Allergic Skin Reactions

Rarely, contact dermatitis or a more pronounced allergic skin reaction may occur. Stop applying the cream and seek medical advice if a significant reaction develops.

When to Seek Medical Attention

Seek prompt medical advice if skin irritation becomes severe, spreads beyond the treated area or continues to worsen. Get emergency medical help if you develop facial or throat swelling, difficulty breathing or other signs of a severe allergic reaction.

This information does not replace the product leaflet or advice from a healthcare professional. Follow the product instructions and consult a healthcare professional if you are concerned about any reaction.

Contraindications

  • Known hypersensitivity to azelaic acid or to propylene glycol or other excipients in the cream
  • Application to broken, infected, or eczematous skin without medical advice
  • Use around the eyes, mouth, nostrils, or on mucous membranes
  • Concurrent use of other harsh or drying topical acne products without spacing them out, as this can worsen irritation

Drug / Food Interactions

  • Minimal systemic absorption means significant drug interactions are unlikely
  • Combining with other topical acne treatments (such as retinoids or benzoyl peroxide) at the same time may increase skin irritation, so alternate application times or space products apart as advised
  • No specific food interactions are expected as this is a topical skin product
  • Inform your pharmacist if you are using other prescription topical treatments on the same area of skin

Quick Tips

  • Apply sunscreen during the day, as treated skin can be more sensitive to sun exposure
  • Avoid contact with the eyes, mouth, and mucous membranes; rinse thoroughly with water if contact occurs
  • Be patient — visible improvement usually takes at least 4 weeks of consistent use
  • Start with once-daily use in the first week if your skin is sensitive, then build up to twice daily
  • Avoid using other strong exfoliating or acne products at the same time without spacing them apart

Ingredients / Active Ingredients

  • Azelaic Acid 20% w/w – the active ingredient
  • Cream base excipients as formulated by the manufacturer to support skin absorption and tolerability

Safety Advice

Pregnancy

Generally Safe

This medicine is generally safe during pregnancy, though minor risks may exist in rare cases.

Breastfeeding

Limited Data

Limited data on excretion in breast milk. Consult a doctor before use.

Kidney

Use With Care

Use cautiously. Dose adjustment or monitoring may be required.

Liver

Use With Care

Use cautiously. Liver function monitoring may be required.

Alcohol

No Data

No data is available regarding the interaction of alcohol with this medicine.

Driving

Generally Safe

This medicine is generally safe and should not impair your driving ability.

Relevant Information

Azelaic acid is often chosen for people who cannot tolerate stronger acne treatments such as retinoids or who have rosacea alongside acne, as it tends to be gentler while still being effective. If irritation is severe or persistent, or if there is no improvement after 2-3 months of consistent use, a doctor or pharmacist should be consulted to review the treatment plan.

How to buy

Go to the DoctorOnCall website

Go to the DoctorOnCall website

Visit the DoctorOnCall website, then choose or search for Skinoren 20% Cream and add it to your cart.

Place your order

Place your order

Review your cart, enter your delivery details and complete your payment securely. No prescription is needed.

Pharmacist dispenses

Pharmacist dispenses

A registered pharmacist reviews your order and prepares your medication in accordance with professional pharmacy standards.

Receive your order

Receive your order

Your order is packed securely and delivered to your address, with fast delivery options available. Check your parcel when it arrives.

Frequently Asked Questions

Product Specifications

BrandSkinoren
ManufacturerLEO Laboratories Limited
ClassificationNon-prescription
Ingredients / Active IngredientsAzelaic Acid
Weight30g
Strength20% w/w
Pack Size30 g tube
DosageApply a thin layer to clean, dry skin as directed on the pack or by your pharmacist.
Shelf LifeTypically 3 years from the date of manufacture. Refer to the expiry date printed on the packaging. Do not use after the expiry date.
Pack Contents1 tube of 30 g cream
Registration holderDKSH Malaysia Sdn. Bhd.
FormCream
RouteTopical use (on the skin only)
Per DoseA thin layer on the affected area
StorageStore below 30°C in a dry place away from direct sunlight. Keep out of reach of children.
ExcipientsContains propylene glycol, among other ingredients. Refer to the package insert for the full list.

Customer Reviews

4.8 · 9 reviews
  • Verified purchase

    Alya Humaira · Purchased: 30g

    Well packed & received. Self collection, so no shopping charges. Found it very affordable.

  • Verified purchase

    Nur Amirah · Purchased: 30g

    Maklumat produk tersusun dan mudah dibaca. Senang untuk rujukan semula.

  • Verified purchase

    Sofea Nadia · Purchased: 30g

    Arrived in 4 days, properly packed and in good condition. Good pricing too.

  • Verified purchase

    Irfan Hakimi · Purchased: 30g

    Senang nak cari produk dan semak maklumat yang dipaparkan.

  • Verified purchase

    Chloe Lim · Purchased: 30g

    Good packing and fast delivery, It is valuable from it's price and quality. Thanks

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Important Medical Information

💊 Recommended Dosage:

A small, pea-sized amount is generally enough to cover the whole face; using more does not improve results and may increase irritation. Some people are advised to start with once-daily application in the first week and build up to twice daily as tolerated, and treatment is usually continued for several months to achieve and maintain results.

🛑 Contraindications (Do not use if):
  • Known hypersensitivity to azelaic acid or to propylene glycol or other excipients in the cream
  • Application to broken, infected, or eczematous skin without medical advice
  • Use around the eyes, mouth, nostrils, or on mucous membranes
  • Concurrent use of other harsh or drying topical acne products without spacing them out, as this can worsen irritation
If you are unsure, please chat with us or consult your doctor.
⚠️ Common Side Effects:
  • Mild burning or stinging on application
  • Skin dryness or peeling
  • Itching or tingling sensation
  • Redness or irritation at the site of application
Stop taking this medication immediately and consult your doctor if you experience severe allergic reactions or side effects.
IMPORTANT: Unsure? Chat with our pharmacists (Mon - Sat, 9:00am - 6:00pm) before buying.