Skinoren 20% Cream

Brand LEO
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Dr. Mohd Izzat Amir Bin Awang
Reviewed byDr. Mohd Izzat Amir Bin AwangDoctor of Medicine (MD), University of Mansoura - Manchester
Dr. Chong Zhan Pong
Written byDr. Chong Zhan PongDoctor of Medicine (MD), International Medical University (IMU)

Last updated:

Overview

Skinoren 20% Cream contains Azelaic Acid 20% w/w – the active ingredient and is presented as a cream. It is supplied in a pack size of 30g.

It is classified as a non-prescription medicine, so no prescription is needed to order it. Under Malaysian rules for medicine information, this page carries product, safety and handling information only.

You can consult a doctor or pharmacist online on DoctorOnCall about this product before or after you order. Every order is checked by a registered pharmacist before it is delivered. Always read the label and the leaflet supplied with the pack.

Directions for Use

Cleanse and dry the affected area of skin thoroughly before use. Apply a thin layer of the cream to the affected areas and gently massage it in, usually twice daily in the morning and evening, washing your hands after application unless the hands themselves are being treated.

Dosage

A small, pea-sized amount is generally enough to cover the whole face; using more does not improve results and may increase irritation. Some people are advised to start with once-daily application in the first week and build up to twice daily as tolerated, and treatment is usually continued for several months to achieve and maintain results.

Shelf Life

Unopened, Skinoren 20% Cream is generally stable until the expiry date printed on the packaging. Once opened, it is best used within the period stated on the carton (commonly several months) as the product’s stability and effectiveness can reduce over time after opening.

Storage Instructions

Store below 25°C in a cool, dry place away from direct sunlight, and keep the tube tightly closed between uses. Keep out of the sight and reach of children, and avoid storing it in direct heat, such as a car dashboard or bathroom windowsill.

Side Effects

  • Mild burning or stinging on application
  • Skin dryness or peeling
  • Itching or tingling sensation
  • Redness or irritation at the site of application

Contraindications

  • Known hypersensitivity to azelaic acid or to propylene glycol or other excipients in the cream
  • Application to broken, infected, or eczematous skin without medical advice
  • Use around the eyes, mouth, nostrils, or on mucous membranes
  • Concurrent use of other harsh or drying topical acne products without spacing them out, as this can worsen irritation

Drug / Food Interactions

  • Minimal systemic absorption means significant drug interactions are unlikely
  • Combining with other topical acne treatments (such as retinoids or benzoyl peroxide) at the same time may increase skin irritation, so alternate application times or space products apart as advised
  • No specific food interactions are expected as this is a topical skin product
  • Inform your pharmacist if you are using other prescription topical treatments on the same area of skin

Quick Tips

  • Apply sunscreen during the day, as treated skin can be more sensitive to sun exposure
  • Avoid contact with the eyes, mouth, and mucous membranes; rinse thoroughly with water if contact occurs
  • Be patient — visible improvement usually takes at least 4 weeks of consistent use
  • Start with once-daily use in the first week if your skin is sensitive, then build up to twice daily
  • Avoid using other strong exfoliating or acne products at the same time without spacing them apart

Ingredients / Active Ingredients

  • Azelaic Acid 20% w/w – the active ingredient
  • Cream base excipients as formulated by the manufacturer to support skin absorption and tolerability

Safety Advice

Pregnancy

Generally Safe

This medicine is generally safe during pregnancy, though minor risks may exist in rare cases.

Breastfeeding

Limited Data

Limited data on excretion in breast milk. Consult a doctor before use.

Kidney

Use With Care

Use cautiously. Dose adjustment or monitoring may be required.

Liver

Use With Care

Use cautiously. Liver function monitoring may be required.

Alcohol

No Data

No data is available regarding the interaction of alcohol with this medicine.

Driving

Generally Safe

This medicine is generally safe and should not impair your driving ability.

Relevant Information

Azelaic acid is often chosen for people who cannot tolerate stronger acne treatments such as retinoids or who have rosacea alongside acne, as it tends to be gentler while still being effective. If irritation is severe or persistent, or if there is no improvement after 2-3 months of consistent use, a doctor or pharmacist should be consulted to review the treatment plan.

Frequently Asked Questions

Product Specifications

BrandLEO
ClassificationNon-prescription
Ingredients / Active IngredientsAzelaic Acid
Weight30g

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Important Medical Information

💊 Recommended Dosage:

A small, pea-sized amount is generally enough to cover the whole face; using more does not improve results and may increase irritation. Some people are advised to start with once-daily application in the first week and build up to twice daily as tolerated, and treatment is usually continued for several months to achieve and maintain results.

🛑 Contraindications (Do not use if):
  • Known hypersensitivity to azelaic acid or to propylene glycol or other excipients in the cream
  • Application to broken, infected, or eczematous skin without medical advice
  • Use around the eyes, mouth, nostrils, or on mucous membranes
  • Concurrent use of other harsh or drying topical acne products without spacing them out, as this can worsen irritation
If you are unsure, please chat with us or consult your doctor.
⚠️ Common Side Effects:
  • Mild burning or stinging on application
  • Skin dryness or peeling
  • Itching or tingling sensation
  • Redness or irritation at the site of application
Stop taking this medication immediately and consult your doctor if you experience severe allergic reactions or side effects.
IMPORTANT: Unsure? Chat with our pharmacists (Mon - Sat, 9:00am - 6:00pm) before buying.