Ultracet 37.5/325mg Tablet

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Brand Janssen
Manufacturer Janssen
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Dr. Mohd Izzat Amir Bin Awang
Reviewed byDr. Mohd Izzat Amir Bin AwangDoctor of Medicine (MD), University of Mansoura - Manchester
Dr. Chong Zhan Pong
Written byDr. Chong Zhan PongDoctor of Medicine (MD), International Medical University (IMU)

Overview

Ultracet 37.5/325mg Tablet is a prescription-only medicine (POM) that contains Tramadol hydrochloride 37.5mg and Paracetamol 325mg. It is supplied as a tablet and is dispensed in Malaysia only against a valid prescription issued by a registered doctor.

Under Malaysian rules for prescription medicines, this page carries product, safety and handling information only. Your doctor or pharmacist will explain whether this medicine is suitable for you, the dose you should take, and how long you should take it.

On DoctorOnCall, Ultracet 37.5/325mg Tablet is reviewed by a licensed doctor through an online consultation and dispensed by a registered pharmacist before delivery. Always follow the instructions on your prescription label and the package insert supplied with the product, and do not share this medicine with anyone else.

Directions for Use

Take Ultracet 37.5/325mg Tablet with or without food, swallowing the tablet whole with water. Do not crush or chew the tablet. Take only when needed for pain and do not take more frequently or for longer than prescribed, as both tramadol and paracetamol carry risks of harm when overused.

Dosage

The usual adult dose of Ultracet 37.5/325mg Tablet is 1-2 tablets every 4-6 hours as needed for pain, not exceeding the maximum daily dose stated by your doctor or pharmacist, and only for the shortest duration needed to control your pain. Your doctor will individualise the dose and duration based on your pain severity, kidney and liver function, and other medicines you are taking.

Side Effects

  • Nausea or vomiting
  • Dizziness or drowsiness
  • Constipation
  • Dry mouth or sweating
  • Serious: slowed or difficult breathing, seizures, severe confusion, or signs of serotonin syndrome (agitation, rapid heartbeat, high fever, muscle twitching) require immediate emergency medical attention

Contraindications

  • Known hypersensitivity to tramadol, paracetamol, or other opioids
  • Acute intoxication with alcohol, sedatives, opioids, or other centrally acting medicines
  • Use of, or within 14 days of, monoamine oxidase inhibitors (MAOIs)
  • Severe liver impairment or uncontrolled epilepsy
  • Severe respiratory depression or acute/severe asthma

Drug / Food Interactions

  • SSRIs, SNRIs, or MAOIs significantly increase the risk of serotonin syndrome when combined with tramadol
  • Alcohol and other sedating medicines (benzodiazepines, sleeping tablets) increase the risk of severe drowsiness and breathing difficulty
  • Warfarin’s blood-thinning effect may be enhanced, requiring closer INR monitoring
  • Other paracetamol-containing products increase the risk of liver damage from excess total paracetamol intake

Quick Tips

  • Never exceed the maximum daily dose or take other paracetamol-containing products at the same time
  • Avoid alcohol while taking this medicine
  • Do not drive or operate machinery until you know how this medicine affects you, as it can cause drowsiness
  • Use only for as long as your doctor advises, as tramadol carries a risk of dependence with prolonged use

Ingredients / Active Ingredients

  • Tramadol hydrochloride 37.5mg
  • Paracetamol 325mg

Frequently Asked Questions

Product Specifications

BrandJanssen
ManufacturerJanssen
ClassificationPrescription medicine
Pack Size10s, 30s
Shelf LifeUse this product before the expiry date stated on the packaging. Do not use the medicine if the expiry date has passed.
Storage InstructionsStore below 30°C in a dry place, away from direct sunlight and out of reach of children.

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