Unasyn 375mg Tablet

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Brand Pfizer
Manufacturer Pfizer
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Dr. Mohd Izzat Amir Bin Awang
Reviewed byDr. Mohd Izzat Amir Bin AwangDoctor of Medicine (MD), University of Mansoura - Manchester
Dr. Adeline Carol Peters
Written byDr. Adeline Carol PetersBachelor of Medicine and Bachelor of Surgery (MBBS) — Manipal Academy of Higher Education (MAHE)

Last updated:

Overview

Unasyn 375mg Tablet contains Ampicillin 250mg (as ampicillin trihydrate) and Sulbactam 125mg (as sulbactam sodium) and is available as a tablet. It is classified as a prescription medicine and may only be obtained with a valid prescription from a registered medical practitioner.

Only product, safety and handling information is published here. Anything beyond that is explained to you directly by your doctor or pharmacist as part of your consultation.

DoctorOnCall is a licensed online pharmacy. Orders for Unasyn 375mg Tablet are processed only after a doctor has assessed your suitability and issued a prescription, and every order is checked by a registered pharmacist before it is sent out.

Directions for Use

Take the tablet with a full glass of water, with or without food, at evenly spaced intervals. Complete the full course even if you feel better before finishing it.

Storage Instructions

Store below 30°C in a dry place, away from direct sunlight and out of reach of children.

Side Effects

  • Nausea or vomiting
  • Diarrhea
  • Skin rash
  • Mild abdominal pain
  • Headache
  • Itching or irritation around the injection site (if given as an injection)

Contraindications

  • Known hypersensitivity to ampicillin, sulbactam, or other penicillin-type antibiotics
  • History of a severe allergic reaction to any beta-lactam antibiotic, including cephalosporins
  • History of ampicillin- or penicillin-associated jaundice or liver problems

Drug / Food Interactions

  • May reduce the effectiveness of hormonal contraceptives – use additional contraception while taking this medicine.
  • Allopurinol combined with ampicillin increases the risk of skin rash.
  • Probenecid can increase and prolong ampicillin blood levels if taken together.
  • Inform your doctor of all medicines you are taking and any known drug allergies before starting this medicine.

Quick Tips

  • Complete the entire prescribed course, even if you feel better after a few days, to prevent antibiotic resistance and treatment failure.
  • Take doses at evenly spaced times to maintain steady antibiotic levels in your body.
  • Report any signs of a severe allergic reaction (widespread rash, swelling of the face or throat, difficulty breathing) immediately.
  • Inform your doctor if diarrhoea becomes severe or persistent, as this could indicate a different condition requiring attention.

Ingredients / Active Ingredients

  • Ampicillin 250mg (as ampicillin trihydrate)
  • Sulbactam 125mg (as sulbactam sodium)

Safety Advice

Pregnancy

Safe If Prescribed

This medicine should only be used during pregnancy if prescribed by a doctor after careful evaluation.

Breastfeeding

Generally Safe

This medicine is generally safe during breastfeeding with minimal risk to the infant.

Kidney

Use With Care

Use cautiously. Dose adjustment or monitoring may be required.

Liver

Use With Care

Use cautiously. Liver function monitoring may be required.

Alcohol

Generally Safe

Consuming alcohol with this medicine is generally safe, but moderate intake is advised.

Driving

Generally Safe

This medicine is generally safe and should not impair your driving ability.

Frequently Asked Questions

Product Specifications

BrandPfizer
ManufacturerPfizer
ClassificationPrescription medicine
Ingredients / Active IngredientsAmpicillin
Pack Size10s
DosageThe usual adult dose is one tablet taken two to three times daily, or as prescribed by your doctor based on the severity and type of infection.
Shelf LifeRefer to the expiry date printed on the packaging.

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