Zaltrap 100mg/4ml Injection

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Prescription Required

Complete your checkout to get your prescription approved. A doctor will contact you within 30 minute(s) after payment.

Overview

Zaltrap 100mg/4ml Injection is a prescription-only medicine (POM) presented as an injection, with Ziv-aflibercept (aflibercept) 100mg/4ml as its active ingredient content.

This page is limited to product, safety and handling information, in line with Malaysian rules on prescription medicine information for the public. Your prescriber or pharmacist is the right source for anything beyond that, together with the leaflet inside the pack.

Through DoctorOnCall, this product is supplied after an online consultation with a licensed doctor and a valid prescription, and it is checked by a registered pharmacist before dispensing. Take it exactly as prescribed, and speak to your doctor before stopping, changing the dose, or starting any other medicine alongside it.

Directions for Use

This medicine is prepared and administered only by trained healthcare professionals as an IV infusion, typically given before the chemotherapy components of the FOLFIRI regimen in the same treatment cycle.

Dosage

Dosing is calculated by the treating oncologist based on body surface area and given as part of a defined FOLFIRI chemotherapy cycle, as a timed intravenous infusion in a hospital or specialist infusion setting.

Shelf Life

Refer to the expiry date printed on the packaging; this medicine is stored and handled only by healthcare facilities.

Storage Instructions

Stored under controlled, refrigerated conditions by the pharmacy or hospital as specified by the manufacturer; not intended for home storage.

Side Effects

  • High blood pressure (hypertension)
  • Low blood cell counts, including neutropenia, which increases infection risk
  • Diarrhoea and mouth sores (stomatitis)
  • Proteinuria (protein in the urine) – a sign of possible kidney effects
  • Bleeding, poor wound healing, and rarely gastrointestinal perforation – all require urgent medical attention

Contraindications

  • Known hypersensitivity to aflibercept or any ingredient in the formulation
  • Recent major surgery, until adequate wound healing has occurred
  • Severe, poorly controlled high blood pressure

Drug / Food Interactions

  • Combining with other medicines that raise blood pressure or increase bleeding risk requires closer monitoring by the oncology team.
  • Concurrent chemotherapy agents can compound low blood count risk.
  • Inform your oncology team of all medicines and supplements you are taking before each cycle.

Quick Tips

  • Attend all scheduled blood pressure checks, as this medicine commonly raises blood pressure and may need additional treatment.
  • Contact your care team immediately if you develop fever, chills, severe abdominal pain, or unusual bleeding.
  • Report protein in urine or swelling to your oncology team, as this is monitored during treatment.
  • Tell your surgical team you are on this medicine well before any planned procedure, due to wound-healing effects.

Frequently Asked Questions

Is Zaltrap 100mg/4ml Injection a prescription medicine?

Yes. Zaltrap 100mg/4ml Injection is a prescription-only medicine (POM). It can only be supplied against a valid prescription written by a registered doctor, and it should be used only by the person named on the prescription label.

What does Zaltrap 100mg/4ml Injection contain?

Zaltrap 100mg/4ml Injection is supplied as an injection and contains Ziv-aflibercept (aflibercept) 100mg/4ml. The full composition is listed in the Composition section on this page and on the product packaging.

Why is there no information here about what Zaltrap 100mg/4ml Injection is for?

Malaysian rules for prescription medicines limit public product pages to product, safety and handling information. Your doctor decides whether this medicine is appropriate for you and will explain it during your consultation, and your pharmacist can answer further questions when the medicine is dispensed.

How should I take Zaltrap 100mg/4ml Injection?

Follow your doctor’s instructions and the directions on the dispensing label without changing them. If anything on the label is unclear, check with your pharmacist before taking the first dose, and read the Directions for Use section on this page.

What should I do if I miss a dose?

Take it as soon as you remember, unless your next dose is nearly due. In that case skip the missed dose and carry on with your usual schedule. Never take two doses together to make up for a missed one. If you miss doses often, tell your doctor or pharmacist.

How should I store Zaltrap 100mg/4ml Injection?

Stored under controlled, refrigerated conditions by the pharmacy or hospital as specified by the manufacturer; not intended for home storage. Keep it in the original pack until use, and do not use it after the expiry date printed on the packaging.

What should I do if I notice side effects?

Tell your doctor or pharmacist about any reaction that concerns you, and seek medical care immediately for signs of a severe reaction such as difficulty breathing, swelling of the face, lips or throat, or a widespread rash. Reported reactions are listed in the Side Effects section on this page.

Can I stop taking Zaltrap 100mg/4ml Injection on my own?

No. Speak to your doctor before stopping, pausing or changing the dose, even if you feel well or think you no longer need the medicine.

How do I get a prescription for Zaltrap 100mg/4ml Injection?

Customers in Malaysia can complete an online consultation with a DoctorOnCall doctor, who decides whether a prescription is appropriate, or upload a valid prescription already issued by their own doctor.

Orders going to Singapore are dispatched from Malaysia as an international delivery, so you need to hold a valid prescription or doctor’s letter for the medicine. Check the consultation and prescription upload options shown at checkout for your delivery address before placing the order.

How long will delivery take?

Within Malaysia, standard delivery takes 3 to 5 working days. Same-day delivery is available in the Klang Valley for orders placed before 12pm; orders placed after 12pm arrive by the end of the next day.

Orders to Singapore are sent as international deliveries and take 5 to 9 working days. A lump-sum shipping and handling fee applies to every overseas delivery and is shown at checkout.

What payment methods can I use?

Customers in Malaysia can pay by FPX online banking, credit or debit card (Visa and Mastercard), and supported e-wallets including Touch ‘n Go eWallet, GrabPay and ShopeePay.

FPX and local e-wallets are tied to Malaysian bank and wallet accounts, so if your delivery address is in Singapore, use the payment options displayed at checkout for that address rather than assuming the same list applies.

Can Zaltrap 100mg/4ml Injection be delivered to Singapore?

Yes. DoctorOnCall ships to Singapore as an international order dispatched from Malaysia, arriving in 5 to 9 working days with a lump-sum shipping and handling fee.

Singapore’s Health Sciences Authority (HSA) allows personal imports of up to three months’ supply of a medicine for your own use or an immediate family member’s, as long as it contains no controlled drugs, psychotropic substances or prohibited items. Keep the product in its original labelled packaging and keep a copy of your prescription or doctor’s letter with it. Quantities above three months’ supply, and medicines containing controlled substances, require prior HSA approval.

Is Zaltrap 100mg/4ml Injection registered with the authorities?

Products listed on DoctorOnCall are registered with Malaysia’s Ministry of Health for supply in Malaysia, and each pack carries its MAL registration number.

An order delivered to Singapore arrives as a personal import of a Malaysia-registered product; HSA product registration is not required for personal-use quantities, but it is also not the same as a product registered for sale in Singapore. If you need a locally registered Singapore product, buy it from a pharmacy in Singapore.

Who do I contact if there is a problem with my order?

DoctorOnCall’s customer care team handles order, delivery and product queries through the contact channels on the site, including WhatsApp and the online help centre.

For deliveries to Singapore, allow more time before chasing an order than you would for a local Malaysian delivery, as the parcel passes through customs clearance and tracking updates can appear later in the journey.

Ingredients / Active Ingredients

  • Ziv-aflibercept (aflibercept) 100mg/4ml

Medical Review

Written by:

Dr. Chong Zhan Pong

Doctor of Medicine (MD), International Medical University (IMU)

Reviewed by:

Dr. Mohd Izzat Amir Bin Awang

Doctor of Medicine (MD), University of Mansoura - Manchester

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