Zestril 10mg Tablet

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Manufacturer AstraZeneca
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Dr. Mohd Izzat Amir Bin Awang
Reviewed byDr. Mohd Izzat Amir Bin AwangDoctor of Medicine (MD), University of Mansoura - Manchester
Dr. Adeline Carol Peters
Written byDr. Adeline Carol PetersBachelor of Medicine and Bachelor of Surgery (MBBS) — Manipal Academy of Higher Education (MAHE)

Last updated:

Overview

Zestril 10mg Tablet is a prescription-only medicine (POM) presented as a tablet, with Lisinopril 10mg as its active ingredient content.

This page is limited to product, safety and handling information, in line with Malaysian rules on prescription medicine information for the public. Your prescriber or pharmacist is the right source for anything beyond that, together with the leaflet inside the pack.

Through DoctorOnCall, this product is supplied after an online consultation with a licensed doctor and a valid prescription, and it is checked by a registered pharmacist before dispensing. Take it exactly as prescribed, and speak to your doctor before stopping, changing the dose, or starting any other medicine alongside it.

Directions for Use

Take Zestril 10mg Tablet exactly as prescribed by your doctor, usually once daily at the same time each day, with or without food. Swallow the tablet whole with a glass of water, and do not stop taking it abruptly without medical advice even if you feel well, as blood pressure control needs to be maintained continuously.

Dosage

The usual maintenance dose for adults with hypertension is 10mg to 20mg once daily, adjusted by the prescribing doctor based on blood pressure response and kidney function. Do not adjust your own dose or share this medicine with another person, as the appropriate dose depends on individual factors such as other medications, kidney function, and the specific condition being treated.

Shelf Life

Zestril 10mg Tablet is typically stable for up to 36 months from the date of manufacture when stored correctly and unopened; always check the expiry date printed on the packaging and do not use the tablets beyond this date.

Storage Instructions

Store below 30°C in a dry place away from direct light and moisture, in the original packaging until ready to use. Keep out of reach of children and pets at all times.

Side Effects

  • Dizziness or lightheadedness
  • Dry cough
  • Headache
  • Fatigue
  • Nausea
  • Low blood pressure
  • Elevated blood potassium levels (hyperkalemia)
  • Rash

Contraindications

  • Known hypersensitivity to lisinopril or any other ACE inhibitor
  • History of angioedema related to previous ACE inhibitor use
  • Pregnancy or planning pregnancy, as ACE inhibitors can harm the developing baby
  • Bilateral renal artery stenosis or significant kidney artery narrowing
  • Hereditary or idiopathic angioedema

Drug / Food Interactions

  • Potassium-sparing diuretics, potassium supplements, or salt substitutes may cause dangerously high potassium levels when combined
  • NSAIDs (such as ibuprofen or diclofenac) may reduce the blood-pressure-lowering effect and affect kidney function
  • Lithium levels may rise when taken with ACE inhibitors, requiring monitoring
  • Other antihypertensive medicines or diuretics may increase the blood-pressure-lowering effect
  • Diabetes medications may have an enhanced blood-sugar-lowering effect

Quick Tips

  • Attend all scheduled follow-up appointments so your doctor can monitor blood pressure and kidney function
  • Rise slowly from sitting or lying down to reduce dizziness, especially when starting treatment
  • Tell your doctor immediately if you notice swelling of the face, lips, or throat, or difficulty breathing
  • Do not use potassium supplements or salt substitutes without discussing this with your doctor
  • Inform your doctor if you become pregnant or are planning to conceive while on this medicine

Ingredients / Active Ingredients

  • Lisinopril 10mg (active ingredient, ACE inhibitor)
  • Standard tablet excipients including fillers and binders
  • Lisinopril 10mg

Safety Advice

Pregnancy

Not Safe

This medicine is not considered safe during pregnancy and should be avoided.

Breastfeeding

Limited Data

Limited data on excretion in breast milk. Consult a doctor before use.

Kidney

Use With Care

Use cautiously. Dose adjustment or monitoring may be required.

Liver

Use With Care

Use cautiously. Liver function monitoring may be required.

Alcohol

Not Advisable

It is not advisable to consume alcohol while taking this medicine.

Driving

Use With Care

Use caution while driving until you know how this medicine affects you.

Relevant Information

Zestril 10mg Tablet requires ongoing medical supervision, as regular blood pressure checks and periodic kidney function and electrolyte monitoring help ensure the medicine continues to work safely and effectively over the long term. Patients should not discontinue treatment on their own, as stopping abruptly can lead to a rebound in blood pressure.

Frequently Asked Questions

Product Specifications

BrandAstraZeneca
ManufacturerAstraZeneca
ClassificationPrescription medicine
Ingredients / Active IngredientsLisinopril
Pack Size14s, 28s

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