Premarin 0.625mg Tablet
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Overview
Premarin 0.625mg Tablet is supplied as a tablet, with Conjugated Estrogens 0.625mg. It is supplied in a pack size of 28s.
No prescription is required for this product, as it is a non-prescription medicine. This page is limited to product, safety and handling information.
If you would like guidance before buying, you can speak to a doctor or pharmacist through an online consultation on DoctorOnCall. Orders are dispensed by a registered pharmacist and delivered to your address.
Directions for Use
Take Premarin exactly as prescribed by your doctor, usually as one tablet daily, swallowed whole with water, at around the same time each day. If your uterus is still intact, your doctor will usually prescribe this together with a progestogen to protect the lining of the womb; do not omit the progestogen component of your regimen unless instructed. Do not stop treatment abruptly without discussing it with your doctor.
Dosage
The dose is individualised based on your symptoms, medical history, and response to treatment; 0.625mg is this is the higher/standard of the two commonly available oral premarin strengths (the other being 300mcg), commonly used as a standard starting dose for menopausal symptom relief. Your doctor will periodically review whether you still need treatment and will aim for the lowest effective dose for the shortest duration needed to control symptoms. If you miss a dose, take it as soon as you remember on the same day; do not double up the next day’s dose.
Shelf Life
Premarin tablets remain stable until the expiry date printed on the packaging when stored correctly and kept in their original blister/container. Do not use the tablets after the expiry date.
Storage Instructions
Store below 30°C in a dry place away from direct sunlight and moisture, in the original packaging to protect the tablets from light. Keep out of the reach and sight of children.
Side Effects
- Breast tenderness or pain
- Headache or migraine
- Nausea or bloating
- Mood swings or depression
- Vaginal spotting or discharge
- Swelling in hands or feet
- Increased risk of blood clots (rare)
Contraindications
- Undiagnosed abnormal vaginal bleeding
- Known, suspected, or past history of breast cancer or other estrogen-dependent cancer
- Current or past history of blood clots in the veins (deep vein thrombosis, pulmonary embolism)
- Current or recent arterial thromboembolic disease such as stroke or heart attack
- Active liver disease or significantly impaired liver function
- Known or suspected pregnancy
- Known hypersensitivity to conjugated estrogens or any ingredient in the tablet
Drug / Food Interactions
- Enzyme-inducing medicines such as rifampicin or certain anticonvulsants (e.g. phenytoin, carbamazepine), which can reduce estrogen’s effectiveness
- St John’s Wort, which may reduce the effectiveness of estrogen therapy
- Thyroid hormone replacement, as estrogen can affect thyroid-binding proteins and may require dose adjustment
- Anticoagulant (blood-thinning) medicines, as estrogen can alter clotting factors
- Grapefruit juice, which may increase blood levels of estrogen
- Corticosteroids, as estrogen may alter how they are metabolised in the body
Quick Tips
- Take your tablet at the same time each day to help maintain steady hormone levels
- Attend regular follow-up visits so your doctor can reassess whether you still need HRT
- Keep up with routine breast examinations and mammograms as advised by your doctor
- Avoid smoking while on estrogen therapy, as it increases the risk of blood clots
- Report any unexpected or heavy vaginal bleeding to your doctor promptly
- Seek urgent care for symptoms of a blood clot such as leg swelling, pain, sudden chest pain, or breathlessness
Frequently Asked Questions
Do I need a prescription to buy Premarin 0.625mg Tablet?
No. Premarin 0.625mg Tablet is a non-prescription product and can be ordered without a prescription. It is still dispensed by a registered pharmacist on DoctorOnCall.
What does Premarin 0.625mg Tablet contain?
Premarin 0.625mg Tablet is a tablet containing Conjugated Estrogens 0.625mg. The full ingredient list is shown in the Composition or Ingredients section on this page and on the product packaging.
What pack sizes does Premarin 0.625mg Tablet come in?
It is supplied in a pack size of 28s. Choose the pack size you need from the options shown on this page before adding the item to your cart.
Why is there no information here about what Premarin 0.625mg Tablet is for?
This page is limited to product, safety and handling information in line with Malaysian rules on medicine information. If you want advice on whether this product suits you, book an online consultation with a doctor or pharmacist on DoctorOnCall.
How should I use Premarin 0.625mg Tablet?
Use it exactly as stated on the pack label, without changing the amount or how often you use it. If anything on the label is unclear, check with a pharmacist before the first use, and read the Directions for Use section on this page.
Can I speak to a doctor or pharmacist about Premarin 0.625mg Tablet before I buy it?
Yes. DoctorOnCall offers online consultations with licensed doctors and registered pharmacists, so you can ask about this product, your existing medicines, or anything on the label before you place an order.
How should I store Premarin 0.625mg Tablet?
Store below 30°C in a dry place away from direct sunlight and moisture, in the original packaging to protect the tablets from light. Keep out of the reach and sight of children. Keep it in its original pack and do not use it after the expiry date printed on the packaging.
What should I do if I notice side effects after using Premarin 0.625mg Tablet?
Stop using the product and speak to a doctor or pharmacist about any reaction that concerns you. Seek medical care immediately for signs of a severe reaction such as difficulty breathing, swelling of the face, lips or throat, or a widespread rash. Reported reactions are listed in the Side Effects section on this page.
How long will delivery take?
Within Malaysia, standard delivery takes 3 to 5 working days. Same-day delivery is available in the Klang Valley for orders placed before 12pm; orders placed after 12pm arrive by the end of the next day.
Orders to Singapore are sent as international deliveries and take 5 to 9 working days. A lump-sum shipping and handling fee applies to every overseas delivery and is shown at checkout.
What payment methods can I use?
Customers in Malaysia can pay by FPX online banking, credit or debit card (Visa and Mastercard), and supported e-wallets including Touch ‘n Go eWallet, GrabPay and ShopeePay.
FPX and local e-wallets are tied to Malaysian bank and wallet accounts, so if your delivery address is in Singapore, use the payment options displayed at checkout for that address rather than assuming the same list applies.
Can Premarin 0.625mg Tablet be delivered to Singapore?
Yes. DoctorOnCall ships to Singapore as an international order dispatched from Malaysia, arriving in 5 to 9 working days with a lump-sum shipping and handling fee.
Singapore’s Health Sciences Authority (HSA) allows personal imports of up to three months’ supply of a medicine for your own use or an immediate family member’s, as long as it contains no controlled drugs, psychotropic substances or prohibited items. Keep the product in its original labelled packaging and keep a copy of your prescription or doctor’s letter with it. Quantities above three months’ supply, and medicines containing controlled substances, require prior HSA approval.
Is Premarin 0.625mg Tablet registered with the authorities?
Products listed on DoctorOnCall are registered with Malaysia’s Ministry of Health for supply in Malaysia, and each pack carries its MAL registration number.
An order delivered to Singapore arrives as a personal import of a Malaysia-registered product; HSA product registration is not required for personal-use quantities, but it is also not the same as a product registered for sale in Singapore. If you need a locally registered Singapore product, buy it from a pharmacy in Singapore.
Who do I contact if there is a problem with my order?
DoctorOnCall’s customer care team handles order, delivery and product queries through the contact channels on the site, including WhatsApp and the online help centre.
For deliveries to Singapore, allow more time before chasing an order than you would for a local Malaysian delivery, as the parcel passes through customs clearance and tracking updates can appear later in the journey.
Ingredients / Active Ingredients
- Conjugated Estrogens 0.625mg
- Lactose and other tablet binders
- Magnesium stearate
- Film coating agents
Safety Advice
Pregnancy
This medicine is not considered safe during pregnancy and should be avoided.
Breastfeeding
Use with caution. Monitor infant for potential adverse reactions.
Kidney
Use cautiously. Dose adjustment or monitoring may be required.
Liver
Not recommended in patients with liver disease.
Alcohol
Caution is advised when consuming alcohol with this medicine.
Driving
This medicine is generally safe and should not impair your driving ability.
Relevant Information
Premarin 0.625mg Tablet is a systemic (oral) form of hormone replacement therapy and works throughout the body, which is different from Premarin 0.625% Vaginal Cream, a local estrogen treatment applied directly to the vagina mainly for vaginal dryness and atrophy with less systemic absorption. Your doctor will help decide which form and strength of estrogen therapy suits your symptoms, and HRT is generally reviewed regularly to use the lowest effective dose for the shortest time needed.
