Ryzodeg Flextouch (Insulin) 100U/ml Pre-filled Pen

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Dr. Mohd Izzat Amir Bin Awang
Reviewed byDr. Mohd Izzat Amir Bin AwangDoctor of Medicine (MD), University of Mansoura - Manchester
Dr. Adeline Carol Peters
Written byDr. Adeline Carol PetersBachelor of Medicine and Bachelor of Surgery (MBBS) — Manipal Academy of Higher Education (MAHE)

Last updated:

Overview

Ryzodeg Flextouch 100U/ml Pre-filled Pen contains Insulin degludec and insulin aspart (co-formulation) 100U/ml and is available as a medicine. It is classified as a prescription medicine and may only be obtained with a valid prescription from a registered medical practitioner.

Only product, safety and handling information is published here. Anything beyond that is explained to you directly by your doctor or pharmacist as part of your consultation.

DoctorOnCall is a licensed online pharmacy. Orders for Ryzodeg Flextouch 100U/ml Pre-filled Pen are processed only after a doctor has assessed your suitability and issued a prescription, and every order is checked by a registered pharmacist before it is sent out.

Directions for Use

Inject Ryzodeg Flextouch 100U/ml Pre-filled Pen subcutaneously into the abdomen, thigh, or upper arm shortly before a main meal, rotating the injection site each time. Because this product contains a rapid-acting component, make sure a meal follows shortly after injection to reduce the risk of hypoglycemia. Do not mix this insulin with any other insulin or solution.

Dosage

The dose of Ryzodeg Flextouch 100U/ml Pre-filled Pen is individualised by your doctor and is usually injected once or twice daily with a main meal, based on your blood glucose readings and overall diabetes treatment plan. Never change your dose without your doctor’s specific instruction.

Storage Instructions

Before first use, store in a refrigerator (2-8°C); do not freeze, and do not use if it has been frozen. Once a pen/cartridge is in use (or carried as a spare), it may be kept at room temperature (below 30°C), away from direct heat and light, for up to 4 weeks; discard it after that period even if some insulin remains, and never share a pen between patients.

Side Effects

  • Low blood sugar (hypoglycaemia)
  • Weight gain
  • Injection site redness or swelling
  • Headache
  • Dizziness
  • Sweating or shakiness

Contraindications

  • Known hypersensitivity to insulin degludec, insulin aspart, or any ingredient in this product
  • During episodes of hypoglycemia (low blood sugar)

Drug / Food Interactions

  • Other glucose-lowering medicines increase the risk of hypoglycemia when combined
  • Beta-blockers and certain other medicines can mask early warning symptoms of hypoglycemia
  • Corticosteroids and some hormonal medicines can raise blood glucose and reduce this insulin’s effect
  • Alcohol can increase the risk and prolong the duration of hypoglycemia, particularly if meals are irregular

Quick Tips

  • Always inject shortly before a main meal, and ensure the meal is eaten as planned to match the rapid-acting component
  • Always carry a fast-acting source of sugar in case of hypoglycemia
  • Rotate injection sites systematically to maintain consistent insulin absorption
  • Do not mix or share this pen with anyone else, even with a new needle

Ingredients / Active Ingredients

  • Insulin degludec and insulin aspart (co-formulation) 100U/ml

Safety Advice

Pregnancy

Safe If Prescribed

This medicine should only be used during pregnancy if prescribed by a doctor after careful evaluation.

Breastfeeding

Generally Safe

This medicine is generally safe during breastfeeding with minimal risk to the infant.

Kidney

Use With Care

Use cautiously. Dose adjustment or monitoring may be required.

Liver

Use With Care

Use cautiously. Liver function monitoring may be required.

Alcohol

Use With Care

Caution is advised when consuming alcohol with this medicine.

Driving

Use With Care

Use caution while driving until you know how this medicine affects you.

Frequently Asked Questions

Product Specifications

BrandNovo Nordisk
ManufacturerNovo Nordisk
ClassificationPrescription medicine
Ingredients / Active IngredientsInsulin
Pack Contents3ml x1 (pen), 3ml x5
Shelf LifeUse this product before the expiry date stated on the packaging. Do not use the medicine if the expiry date has passed.

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Important Medical Information

💊 Recommended Dosage:

The dose of Ryzodeg Flextouch 100U/ml Pre-filled Pen is individualised by your doctor and is usually injected once or twice daily with a main meal, based on your blood glucose readings and overall diabetes treatment plan. Never change your dose without your doctor’s specific instruction.

🛑 Contraindications (Do not use if):
  • Known hypersensitivity to insulin degludec, insulin aspart, or any ingredient in this product
  • During episodes of hypoglycemia (low blood sugar)
If you are unsure, please chat with us or consult your doctor.
⚠️ Common Side Effects:
  • Low blood sugar (hypoglycaemia)
  • Weight gain
  • Injection site redness or swelling
  • Headache
  • Dizziness
  • Sweating or shakiness
Stop taking this medication immediately and consult your doctor if you experience severe allergic reactions or side effects.
IMPORTANT: Unsure? Chat with our pharmacists (Mon - Sat, 9:00am - 6:00pm) before buying.