Duopharma Vascor 20mg Tablet

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Dr. Mohd Izzat Amir Bin Awang
Reviewed byDr. Mohd Izzat Amir Bin AwangDoctor of Medicine (MD), University of Mansoura - Manchester
Dr. Chong Zhan Pong
Written byDr. Chong Zhan PongDoctor of Medicine (MD), International Medical University (IMU)

Overview

Duopharma Vascor 20mg Tablet contains Simvastatin 20mg and is available as a tablet. It is classified as a prescription medicine and may only be obtained with a valid prescription from a registered medical practitioner.

Only product, safety and handling information is published here. Anything beyond that is explained to you directly by your doctor or pharmacist as part of your consultation.

DoctorOnCall is a licensed online pharmacy. Orders for Duopharma Vascor 20mg Tablet are processed only after a doctor has assessed your suitability and issued a prescription, and every order is checked by a registered pharmacist before it is sent out.

Directions for Use

Take Duopharma Vascor 20mg Tablet once daily in the evening, with or without food, as cholesterol production is highest overnight. Swallow the tablet whole with a glass of water. Avoid taking it with grapefruit juice. Continue taking it even if you feel well, since high cholesterol usually has no symptoms.

Dosage

The usual dose of Duopharma Vascor 20mg Tablet is taken once daily in the evening, typically starting at 10-20mg and adjusted by your doctor up to a maximum of 40mg daily based on your cholesterol response and risk factors. Your doctor will individualise the dose and may lower it if you are also taking certain interacting medicines.

Side Effects

  • Headache
  • Muscle pain or weakness
  • Nausea or stomach discomfort
  • Constipation
  • Dizziness
  • Elevated liver enzymes (in rare cases)

Contraindications

  • Known hypersensitivity to simvastatin or any ingredient in this product
  • Active liver disease or unexplained persistent elevation of liver enzymes
  • Pregnancy and breastfeeding
  • Concomitant use with strong CYP3A4 inhibitors (e.g. itraconazole, ketoconazole, HIV protease inhibitors, clarithromycin)
  • Concomitant use with gemfibrozil, ciclosporin, or danazol

Drug / Food Interactions

  • Grapefruit juice can significantly raise simvastatin blood levels and increase the risk of muscle-related side effects – avoid it
  • Amlodipine and other CYP3A4-interacting medicines may require a lower simvastatin dose (usually capped at 20mg daily) when combined
  • Gemfibrozil, ciclosporin, and danazol should not be combined with simvastatin due to a markedly increased risk of myopathy
  • Warfarin’s blood-thinning effect may be enhanced, requiring closer INR monitoring

Quick Tips

  • Take in the evening for the best cholesterol-lowering effect
  • Avoid grapefruit juice while on this medicine
  • Report unexplained muscle pain, tenderness, or weakness to your doctor promptly
  • Attend scheduled blood tests to monitor cholesterol and liver function
  • Tell your doctor about all other medicines you take, especially for cholesterol or fungal infections

Ingredients / Active Ingredients

  • Simvastatin 20mg

Safety Advice

Pregnancy

Not Advisable

Use during pregnancy is generally not recommended unless absolutely necessary.

Breastfeeding

Not Advisable

Generally not recommended while breastfeeding.

Kidney

Use With Care

Use cautiously. Dose adjustment or monitoring may be required.

Liver

Use With Care

Use cautiously. Liver function monitoring may be required.

Alcohol

Use With Care

Caution is advised when consuming alcohol with this medicine.

Driving

Use With Care

Use caution while driving until you know how this medicine affects you.

Frequently Asked Questions

Product Specifications

BrandDuopharma
ClassificationPrescription medicine
Ingredients / Active IngredientsSimvastatin
Pack Size10s, 120s
Shelf LifeUse this product before the expiry date stated on the packaging. Do not use the medicine if the expiry date has passed.
Storage InstructionsStore below 30°C in a dry place, away from direct sunlight and out of reach of children.

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