Pharmaniaga Simvastatin 40mg Tablet

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Manufacturer Pharmaniaga
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Dr. Mohd Izzat Amir Bin Awang
Reviewed byDr. Mohd Izzat Amir Bin AwangDoctor of Medicine (MD), University of Mansoura - Manchester
Dr. Adeline Carol Peters
Written byDr. Adeline Carol PetersBachelor of Medicine and Bachelor of Surgery (MBBS) — Manipal Academy of Higher Education (MAHE)

Last updated:

Overview

Pharmaniaga Simvastatin 40mg Tablet is a prescription-only medicine (POM) that contains Simvastatin 40mg. It is supplied as a tablet and is dispensed in Malaysia only against a valid prescription issued by a registered doctor.

Under Malaysian rules for prescription medicines, this page carries product, safety and handling information only. Your doctor or pharmacist will explain whether this medicine is suitable for you, the dose you should take, and how long you should take it.

On DoctorOnCall, Pharmaniaga Simvastatin 40mg Tablet is reviewed by a licensed doctor through an online consultation and dispensed by a registered pharmacist before delivery. Always follow the instructions on your prescription label and the package insert supplied with the product, and do not share this medicine with anyone else.

Directions for Use

Take Pharmaniaga Simvastatin 40mg Tablet once daily in the evening, with or without food, as simvastatin works with the body’s natural night-time cholesterol production cycle. Swallow the tablet whole with a glass of water and try to take it at the same time each evening.

Dosage

The usual dose of Pharmaniaga Simvastatin 40mg Tablet is 10-40mg once daily, started low and adjusted by your doctor based on your cholesterol response and cardiovascular risk. Higher doses are used less often because of an increased risk of muscle-related side effects. Your doctor will determine the right dose and monitoring schedule for you.

Storage Instructions

Store below 30°C in a dry place, away from direct sunlight and out of reach of children.

Side Effects

  • Headache
  • Muscle pain or weakness
  • Nausea or stomach discomfort
  • Constipation
  • Dizziness
  • Elevated liver enzymes (in rare cases)

Contraindications

  • Known hypersensitivity to simvastatin or any ingredient in this product
  • Active liver disease or unexplained persistent elevation of liver enzymes
  • Pregnancy and breastfeeding
  • Concomitant use with strong CYP3A4 inhibitors (e.g. itraconazole, ketoconazole, HIV protease inhibitors) or gemfibrozil

Drug / Food Interactions

  • Grapefruit juice in large amounts can raise simvastatin blood levels and increase the risk of muscle side effects – avoid regular large-volume intake
  • Gemfibrozil and other fibrates substantially increase the risk of myopathy when combined with simvastatin
  • CYP3A4 inhibitors such as itraconazole, clarithromycin, and erythromycin increase simvastatin blood levels
  • Warfarin’s blood-thinning effect may be enhanced, requiring closer INR monitoring

Quick Tips

  • Take in the evening for the best cholesterol-lowering effect
  • Avoid large amounts of grapefruit juice while on this medicine
  • Report unexplained muscle pain, tenderness, or weakness to your doctor promptly
  • Attend scheduled blood tests to monitor cholesterol and liver function

Ingredients / Active Ingredients

  • Simvastatin 40mg

Safety Advice

Pregnancy

Not Advisable

Use during pregnancy is generally not recommended unless absolutely necessary.

Breastfeeding

Not Advisable

Generally not recommended while breastfeeding.

Kidney

Use With Care

Use cautiously. Dose adjustment or monitoring may be required.

Liver

Use With Care

Use cautiously. Liver function monitoring may be required.

Alcohol

Use With Care

Caution is advised when consuming alcohol with this medicine.

Driving

Use With Care

Use caution while driving until you know how this medicine affects you.

Frequently Asked Questions

Product Specifications

BrandPharmaniaga
ManufacturerPharmaniaga
ClassificationPrescription medicine
Ingredients / Active IngredientsSimvastatin
Pack Size10s, 120s
Shelf LifeUse this product before the expiry date stated on the packaging. Do not use the medicine if the expiry date has passed.

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