Zyloric 300mg Tablet

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Brand Aspen
Manufacturer Aspen
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Dr. Mohd Izzat Amir Bin Awang
Reviewed byDr. Mohd Izzat Amir Bin AwangDoctor of Medicine (MD), University of Mansoura - Manchester
Dr. Adeline Carol Peters
Written byDr. Adeline Carol PetersBachelor of Medicine and Bachelor of Surgery (MBBS) — Manipal Academy of Higher Education (MAHE)

Last updated:

Overview

Zyloric 300mg Tablet is a prescription-only medicine (POM) presented as a tablet, with Allopurinol 300mg as its active ingredient content.

This page is limited to product, safety and handling information, in line with Malaysian rules on prescription medicine information for the public. Your prescriber or pharmacist is the right source for anything beyond that, together with the leaflet inside the pack.

Through DoctorOnCall, this product is supplied after an online consultation with a licensed doctor and a valid prescription, and it is checked by a registered pharmacist before dispensing. Take it exactly as prescribed, and speak to your doctor before stopping, changing the dose, or starting any other medicine alongside it.

Directions for Use

Take Zyloric 300mg Tablet after food to reduce stomach upset, and drink plenty of fluids each day unless your doctor advises otherwise, as this helps prevent kidney stone formation. Continue taking it regularly even between gout attacks, as it works to prevent future attacks rather than to relieve pain during a current one.

Dosage

The dose of Zyloric 300mg Tablet is individualised based on your blood uric acid level and kidney function, and your doctor will typically start at a lower dose and adjust it gradually to reach your target uric acid level. Do not start this medicine during an acute gout attack, as starting it can temporarily worsen the flare – your doctor will advise the right time to begin.

Storage Instructions

Store below 30°C in a dry place, away from direct sunlight and out of reach of children.

Side Effects

  • Skin rash or itching
  • Nausea or vomiting
  • Diarrhoea
  • Drowsiness or dizziness
  • Headache
  • Mild joint pain
  • Change in taste

Contraindications

  • Known hypersensitivity to allopurinol or any ingredient in this product
  • A previous severe skin reaction to allopurinol
  • Asymptomatic hyperuricaemia alone, without gout, kidney stones, or another specific indication, in most cases

Drug / Food Interactions

  • Azathioprine and mercaptopurine levels are markedly increased by allopurinol, requiring a substantial dose reduction of these medicines if combined
  • Ampicillin and amoxicillin combined with allopurinol increase the risk of skin rash
  • Warfarin’s blood-thinning effect may be enhanced, requiring closer INR monitoring
  • ACE inhibitors and thiazide diuretics may increase the risk of hypersensitivity reactions when combined with allopurinol

Quick Tips

  • Continue taking this medicine regularly even when you feel well, as it prevents future gout attacks rather than treating pain
  • Drink plenty of water throughout the day unless your doctor advises otherwise
  • Stop the medicine and seek urgent medical attention if you develop a skin rash, especially with fever or mouth sores
  • Tell your doctor about all your other medicines, as several interact significantly with allopurinol

Ingredients / Active Ingredients

  • Allopurinol 300mg

Safety Advice

Pregnancy

Use With Care

This medicine should be used cautiously during pregnancy. Monitoring may be required.

Breastfeeding

Limited Data

Limited data on excretion in breast milk. Consult a doctor before use.

Kidney

Use With Care

Use cautiously. Dose adjustment or monitoring may be required.

Liver

Use With Care

Use cautiously. Liver function monitoring may be required.

Alcohol

Not Advisable

It is not advisable to consume alcohol while taking this medicine.

Driving

Use With Care

Use caution while driving until you know how this medicine affects you.

Frequently Asked Questions

Product Specifications

BrandAspen
ManufacturerAspen
ClassificationPrescription medicine
Ingredients / Active IngredientsAllopurinol
Pack Size10s, 30s
Shelf LifeUse this product before the expiry date stated on the packaging. Do not use the medicine if the expiry date has passed.

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