Zyloric 100mg Tablet
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Overview
Zyloric 100mg Tablet contains allopurinol 100mg, a xanthine oxidase inhibitor used to reduce high uric acid levels in the blood and to prevent recurrent attacks of gout, as well as to manage certain conditions involving excess uric acid such as recurrent kidney stones. It is a long-term preventive treatment rather than a medicine for treating a sudden gout attack.
Allopurinol works by blocking the enzyme xanthine oxidase, which the body normally uses to convert purines into uric acid. By reducing uric acid production, it lowers blood uric acid levels over time, which helps prevent new urate crystals from forming in joints and reduces the frequency of gout flares.
How it Works
Allopurinol and its active metabolite oxypurinol inhibit xanthine oxidase, the enzyme responsible for converting hypoxanthine to xanthine and then to uric acid. This lowers the amount of uric acid produced by the body, gradually reducing blood urate levels and, over months, shrinking existing urate deposits.
Directions for Use
Take Zyloric 100mg Tablet after food to reduce stomach upset, with a full glass of water, and drink plenty of fluids throughout the day to help prevent kidney stone formation. Continue taking this medicine regularly even during a gout flare, unless your doctor tells you otherwise, as stopping and restarting can make attacks more frequent.
Dosage
The usual starting dose of Zyloric 100mg Tablet is a low dose once daily, which your doctor will gradually increase every few weeks based on regular blood uric acid measurements, until your target level is reached; the maintenance dose varies between individuals depending on response and kidney function.
Shelf Life
Use this product before the expiry date stated on the packaging. Do not use the medicine if the expiry date has passed.
Storage Instructions
Store below 30°C in a dry place, away from direct sunlight and out of reach of children.
Side Effects
- Skin rash or itching
- Nausea or vomiting
- Diarrhoea
- Drowsiness or dizziness
- Headache
- Mild joint pain
- Change in taste
Contraindications
- Known hypersensitivity to allopurinol or any ingredient in this product
- Starting allopurinol for the first time during an acute gout attack (start only once the attack has settled, unless already established on treatment)
Drug / Food Interactions
- Azathioprine and mercaptopurine: allopurinol significantly increases their blood levels, so a substantial dose reduction of these medicines is usually required to avoid serious toxicity
- Ampicillin or amoxicillin: combined use increases the risk of skin rash
- Warfarin: allopurinol can enhance its blood-thinning effect, requiring closer monitoring
- Thiazide diuretics may increase the risk of hypersensitivity reactions when combined with allopurinol, particularly in kidney impairment
Quick Tips
- Drink plenty of water each day while taking this medicine to help prevent kidney stones
- Continue taking allopurinol regularly even if you have a gout flare-up, unless your doctor advises otherwise
- Limit alcohol and purine-rich foods (organ meats, some seafood) as they can raise uric acid levels
- Report any new skin rash immediately, as some allopurinol-related skin reactions can become serious if not caught early
Frequently Asked Questions
What is Zyloric 100mg Tablet used for?
Zyloric 100mg Tablet is used to lower high uric acid levels in the blood and prevent recurrent gout attacks over the long term. It is also sometimes used to prevent certain types of kidney stones associated with high uric acid.
Will this medicine stop a gout attack I am having right now?
No, allopurinol does not relieve an acute gout attack and can even temporarily make it worse when first started, as uric acid levels shift. Your doctor will usually treat an active flare with a different, faster-acting anti-inflammatory medicine while continuing allopurinol.
Why might my gout attacks become more frequent when I start this medicine?
As allopurinol lowers uric acid levels, existing urate crystals in the joints can be mobilised, sometimes triggering more frequent attacks in the first few months. Your doctor may prescribe a preventive anti-inflammatory medicine during this period, and attacks usually settle with continued treatment.
Can I stop taking allopurinol once my gout improves?
No, do not stop without consulting your doctor. Gout is a long-term condition related to persistently high uric acid, and stopping allopurinol usually causes uric acid levels, and the risk of attacks, to rise again.
What should I do if I miss a dose of Zyloric 100mg Tablet?
Take the missed dose as soon as you remember, unless it is almost time for your next dose – in that case, skip the missed dose and continue as normal. Do not double the dose.
Can I buy Zyloric 100mg Tablet from DoctorOnCall?
Yes, Zyloric 100mg Tablet is available through DoctorOnCall, a licensed online pharmacy serving our Malaysian and Singaporean customers. As this is a prescription medicine, you will need to complete an online consultation so a doctor can assess your suitability and issue a valid prescription before the order is processed. This ensures the medicine is appropriate for your condition and used under proper medical supervision, whether you are ordering from Malaysia or Singapore.
Is the medication provided by DoctorOnCall genuine and safe to use?
DoctorOnCall sources its medicines through appropriate licensed pharmacy supply channels for our Malaysian and Singaporean customers. All orders are dispensed and checked by a registered pharmacist before delivery. Always use Zyloric 100mg Tablet according to your doctor’s instructions and the information provided with the product.
What payment methods does DoctorOnCall accept?
We accept payment via Online Banking, Credit Card, and e-Wallets (Boost, GrabPay) for our Malaysian and Singaporean customers, so you can choose whichever method is most convenient for you at checkout.
Does DoctorOnCall provide an installment payment plan for Zyloric 100mg Tablet?
DoctorOnCall provides an installment payment plan for eligible Malaysian and Singaporean customers, where applicable. Available plans, eligibility, and terms can vary by market, so please contact DoctorOnCall Customer Service for the latest information on installment options for your order.
Is delivery free, and how much does shipping for Zyloric 100mg Tablet cost?
Delivery charges may vary for our Malaysian and Singaporean customers depending on your delivery location and the applicable order terms at the time of purchase. For the most accurate and up-to-date delivery fee information, please contact DoctorOnCall Customer Service before placing your order.
How long does delivery take for Zyloric 100mg Tablet?
Our Malaysian customers can generally expect delivery within 3-5 working days, while our Singaporean customers generally receive their orders within 5-7 working days. These are expected timeframes rather than guarantees, and actual delivery time may vary depending on your delivery location, order processing time, courier operations, and whether the order falls on a weekend or public holiday.
What is DoctorOnCall’s shipping, return, or cancellation policy for Zyloric 100mg Tablet?
Shipping, return, and cancellation terms may vary for our Malaysian and Singaporean customers depending on the product and your order details. Please refer to DoctorOnCall’s Shipping & Delivery Policy and Return, Refund & Exchange Policy, or contact Customer Service, for the specific terms that apply to your order.
Ingredients / Active Ingredients
- Allopurinol 100mg
Safety Advice
Pregnancy
This medicine should be used cautiously during pregnancy. Monitoring may be required.
Breastfeeding
Limited data on excretion in breast milk. Consult a doctor before use.
Kidney
Use cautiously. Dose adjustment or monitoring may be required.
Liver
Use cautiously. Liver function monitoring may be required.
Alcohol
It is not advisable to consume alcohol while taking this medicine.
Driving
Use caution while driving until you know how this medicine affects you.
Medical Review
