21st Century VegeSamin 500mg Capsule

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Dr. Mohd Izzat Amir Bin Awang
Reviewed byDr. Mohd Izzat Amir Bin AwangDoctor of Medicine (MD), University of Mansoura - Manchester
Dr. Adeline Carol Peters
Written byDr. Adeline Carol PetersBachelor of Medicine and Bachelor of Surgery (MBBS) — Manipal Academy of Higher Education (MAHE)

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Overview

21st Century VegeSamin 500mg Capsule is a glucosamine supplement from 21st Century, providing 500mg of glucosamine hydrochloride per capsule. What sets VegeSamin apart from most glucosamine products is its source: the glucosamine is derived from corn rather than from the shells of shrimp, crab or other shellfish. This makes it a vegetarian, shellfish-free option for adults who prefer to avoid animal-derived glucosamine.

Glucosamine is an amino sugar that the body naturally produces and uses as a building block for glycosaminoglycans, which are structural components of cartilage and the fluid that lubricates the joints. Glucosamine supplements are commonly taken by adults as nutritional support for joint and cartilage health, particularly in middle age and later life. Research findings on glucosamine have been mixed, with some people reporting benefit and others noticing little change, so it is best viewed as a dietary supplement rather than a replacement for medical care.

VegeSamin is supplied as easy-to-swallow capsules, and the pack listed on DoctorOnCall contains 30 capsules. It is generally taken with meals to help reduce stomach discomfort. Because it is made from a non-shellfish source, it may be a suitable glucosamine option for people who follow a vegetarian diet or who wish to avoid shellfish-derived ingredients, although anyone with allergies should still read the full ingredient list on the label.

Directions for Use

Swallow the capsule whole with a glass of water during or after a meal. Taking glucosamine with food may help reduce stomach discomfort. Follow the serving size on the product label or as advised by your doctor or pharmacist, and do not exceed the recommended amount.

Dosage

Adults: 1 to 2 capsules daily with meals (500mg to 1,000mg of glucosamine hydrochloride per day), or as directed by your doctor or pharmacist. Please follow the serving instructions printed on the product label.

This product is intended for adults. Glucosamine is usually taken consistently over several weeks, as any effect is not immediate. Do not exceed the recommended daily intake, and if you miss a dose, simply continue with your next usual dose.

Storage Instructions

Store in a cool, dry place away from direct sunlight, heat and moisture. Keep the bottle tightly closed after use and keep out of reach of children. Please also follow any storage instructions printed on the product label.

Side Effects

  • Common: Mild stomach upset, nausea, heartburn or bloating.
  • Common: Diarrhoea, constipation or wind.
  • Uncommon: Headache or drowsiness.
  • Uncommon: Changes in blood sugar readings in some people with diabetes.
  • Serious (rare): Allergic reactions such as rash, itching, swelling of the face or lips, or difficulty breathing — stop use and seek urgent medical attention.

Contraindications

  • Known allergy or hypersensitivity to glucosamine or any other ingredient in the product.
  • Children and adolescents, as the product is intended for adults.
  • Pregnancy and breastfeeding, unless advised by a doctor, because there is limited safety information.

Drug / Food Interactions

  • Warfarin and other anticoagulants: glucosamine has been associated with an increased risk of bleeding and raised INR in people taking warfarin — do not start without your doctor’s advice and INR monitoring.
  • Diabetes medicines: glucosamine may raise blood sugar in some people — monitor your blood glucose and inform your doctor.
  • Other joint supplements: check the labels of other glucosamine or joint-support products to avoid taking duplicate amounts.
  • Food: no specific food interaction is known; taking the capsule with meals may improve stomach tolerance.

Quick Tips

  • Take VegeSamin with a meal to help reduce the chance of stomach discomfort.
  • Be consistent — glucosamine is usually taken daily for several weeks before any change is noticed.
  • Combine supplementation with regular low-impact exercise and maintaining a healthy body weight.
  • If you have diabetes, check your blood sugar more closely during the first few weeks.
  • Tell your doctor or pharmacist about all supplements you take, especially if you use warfarin.
  • Keep the bottle tightly closed and store it away from humid areas such as the bathroom.

Ingredients / Active Ingredients

  • Glucosamine hydrochloride (corn-derived, non-shellfish): 500mg per capsule
  • Key ingredient (per capsule): Glucosamine hydrochloride 500mg, derived from corn (non-shellfish source).
  • Serving information: 1 to 2 capsules daily with meals, or as stated on the product label.
  • Dietary suitability: Vegetarian, shellfish-free glucosamine source.
  • Pack size: 30 capsules.
  • Other ingredients: Please refer to the product label for the full list of excipients and capsule materials.

Safety Advice

Pregnancy

Use With Care

This medicine should be used cautiously during pregnancy. Monitoring may be required.

Breastfeeding

Safe

This medicine is safe to use while breastfeeding.

Kidney

Use With Care

Use cautiously. Dose adjustment or monitoring may be required.

Liver

Use With Care

Use cautiously. Liver function monitoring may be required.

Alcohol

Use With Care

Caution is advised when consuming alcohol with this medicine.

Driving

Use With Care

Use caution while driving until you know how this medicine affects you.

Relevant Information

Precautions: Use with caution if you have diabetes or pre-diabetes, as glucosamine may affect blood sugar in some people. People with asthma, high cholesterol, high blood pressure or kidney problems should seek advice before starting a glucosamine supplement. Although VegeSamin is made from a non-shellfish source, people with severe food allergies should still check the full ingredient list. There is limited safety information for pregnancy and breastfeeding.

When to See a Doctor or Pharmacist: Speak to a doctor or pharmacist before use if you take warfarin or other blood thinners, diabetes medicines, or several other medicines, or if you have a chronic medical condition. See a doctor if your joint pain is severe, sudden, accompanied by swelling, redness or fever, or is getting worse, as these symptoms need proper medical assessment. Stop use and seek medical help if you experience an allergic reaction or unusual bruising or bleeding.

Frequently Asked Questions

Product Specifications

Brand21st Century
ClassificationNon-prescription
Ingredients / Active IngredientsGlucosamine
Pack Size30s
Shelf LifeRefer to the expiry date printed on the product packaging. Do not use the capsules after the expiry date.

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