Avelac Syrup

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Dr. Mohd Izzat Amir Bin Awang
Reviewed byDr. Mohd Izzat Amir Bin AwangDoctor of Medicine (MD), University of Mansoura - Manchester
Dr. Adeline Carol Peters
Written byDr. Adeline Carol PetersBachelor of Medicine and Bachelor of Surgery (MBBS) — Manipal Academy of Higher Education (MAHE)

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Overview

Avelac Syrup is an oral solution with Lactulose 667mg per mL as its active ingredient, supplied in a 100ml bottle. Lactulose is a synthetic disaccharide sugar belonging to the osmotic laxative class of ingredients, a category of oral solutions that work within the bowel rather than being absorbed into the bloodstream. Avelac is formulated as a clear, viscous syrup intended to be taken by mouth, measured using an oral measuring device.

As a synthetic disaccharide, lactulose is not significantly broken down or absorbed in the small intestine; it passes largely intact into the colon, where it is handled differently from ordinary dietary sugars. This distinguishes lactulose from stimulant-type laxative ingredients, which act through a different chemical pathway. Avelac’s liquid form allows the dose to be adjusted in small increments by volume, which is a feature of this dosage form rather than of a particular tablet strength.

Avelac Syrup is sold in Malaysia as an OTC (Over-the-Counter) product, suitable for use across different age groups under appropriate dosing guidance. As with any OTC product, check the packaging for the exact ingredient list, batch number, and expiry date, and consult a pharmacist if you are unsure whether this product is suitable for you.

Directions for Use

  • Measure the prescribed dose using the oral syringe or measuring cup provided, or a standard medicine measuring spoon.
  • Avelac Syrup can be taken directly by mouth, or mixed with a small amount of water or juice if preferred.
  • Take at a consistent time each day, with or without food.
  • Shake the bottle gently before each use if separation of the syrup is noticed.

Dosage

Adult dosing for lactulose 667mg/mL oral solutions of this type is typically an initial dose of 15-45ml daily, taken as a single dose or in two divided doses, adjusted to a usual maintenance dose of around 15-30ml daily once a response is established. For children, dosing is weight and age-dependent and should follow the specific guidance on the pack insert or a doctor’s or pharmacist’s instructions rather than an adult dose scaled down informally.

Do not exceed the dose advised by a doctor or pharmacist, or the maximum stated on the packaging. The full effect of an osmotic laxative syrup of this type can take one to two days to become apparent, so the dose should not be increased again within that window without professional advice. If a dose is missed, take it as soon as remembered unless it is almost time for the next dose. Stop use and see a doctor if there is no bowel response after several days of regular use, or if you experience severe abdominal pain.

Storage Instructions

Store below 30°C, away from direct sunlight, and out of reach of children. Keep the bottle tightly closed when not in use, and do not refrigerate unless otherwise stated on the packaging.

Side Effects

  • Bloating or gas
  • Stomach cramps
  • Diarrhoea
  • Nausea
  • Flatulence
  • Electrolyte imbalance (with long-term use)

Contraindications

  • Known hypersensitivity to lactulose or any other ingredient in this syrup.
  • Galactosaemia, a rare inherited condition, because lactulose formulations may contain small amounts of galactose or lactose-related sugars.
  • Intestinal obstruction or suspected bowel blockage.
  • Acute, undiagnosed abdominal pain, where the cause of symptoms has not been assessed by a doctor.

Drug / Food Interactions

  • Non-absorbable antacids may reduce the effectiveness of lactulose, since lactulose’s action depends on bacterial fermentation in the colon; if both are prescribed, ask a pharmacist about spacing the doses.
  • Taking lactulose together with other laxative products may increase the risk of diarrhoea and electrolyte disturbance; avoid combining laxative products unless advised by a doctor.
  • No clinically significant food interactions are established; lactulose syrup can be taken with or without meals.

Quick Tips

  • Always measure the dose with the oral syringe or measuring cup provided rather than a kitchen spoon.
  • Drink enough plain water through the day while taking this syrup.
  • Allow one to two days of regular use before judging whether the dose needs adjusting.
  • Do not combine with other laxative products without checking with a pharmacist first.
  • Shake gently before use if the syrup appears to have separated.
  • Keep the bottle out of reach of children, as its sweet taste may encourage accidental ingestion.

Ingredients / Active Ingredients

  • Active ingredient: Lactulose 667mg per mL.
  • Lactulose is a synthetic disaccharide belonging to the osmotic laxative class of ingredients.
  • Supplied as an oral solution (syrup) in a 100ml bottle.
  • Full excipient (inactive ingredient) information, including flavouring agents, is not publicly disclosed; refer to the product packaging or a pharmacist for a complete list.

Safety Advice

Pregnancy

Safe If Prescribed

This medicine should only be used during pregnancy if prescribed by a doctor after careful evaluation.

Breastfeeding

Generally Safe

This medicine is generally safe during breastfeeding with minimal risk to the infant.

Kidney

Generally Safe

Generally safe, but caution may be required in some patients.

Liver

Use With Care

Use cautiously. Liver function monitoring may be required.

Alcohol

Use With Care

Caution is advised when consuming alcohol with this medicine.

Driving

Generally Safe

This medicine is generally safe and should not impair your driving ability.

Relevant Information

Precautions: Use with caution in people with diabetes, as lactulose syrup contains fermentable sugars that can affect blood glucose monitoring in some individuals; a doctor or pharmacist can advise on suitability. Use with caution in elderly or frail patients, who are more susceptible to fluid and electrolyte disturbance from prolonged diarrhoea. Seek medical advice before use during pregnancy or breastfeeding, although lactulose is generally considered to have a well-established safety profile when used under guidance.

When to See a Doctor or Pharmacist: Speak to a doctor or pharmacist if you have diabetes, galactosaemia, or a history of bowel disease before starting this product. Seek medical attention if there is no response after several days of regular use, if diarrhoea becomes severe or persistent, or if you notice signs of dehydration such as excessive thirst, dizziness, or reduced urination.

Frequently Asked Questions

Product Specifications

ClassificationNon-prescription
Ingredients / Active IngredientsLactulose
Volume100ml
Shelf LifeUse Avelac Syrup before the expiry date printed on the bottle and outer packaging.

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