Baraclude 0.5mg Tablet

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Dr. Mohd Izzat Amir Bin Awang
Reviewed byDr. Mohd Izzat Amir Bin AwangDoctor of Medicine (MD), University of Mansoura - Manchester
Dr. Adeline Carol Peters
Written byDr. Adeline Carol PetersBachelor of Medicine and Bachelor of Surgery (MBBS) — Manipal Academy of Higher Education (MAHE)

Last updated:

Overview

Baraclude 0.5mg Tablet is a prescription-only medicine (POM) that contains Entecavir 0.5mg. It is supplied as a tablet and is dispensed in Malaysia only against a valid prescription issued by a registered doctor.

Under Malaysian rules for prescription medicines, this page carries product, safety and handling information only. Your doctor or pharmacist will explain whether this medicine is suitable for you, the dose you should take, and how long you should take it.

On DoctorOnCall, Baraclude 0.5mg Tablet is reviewed by a licensed doctor through an online consultation and dispensed by a registered pharmacist before delivery. Always follow the instructions on your prescription label and the package insert supplied with the product, and do not share this medicine with anyone else.

Directions for Use

Take Baraclude 0.5mg Tablet on an empty stomach, at least 2 hours before or 2 hours after a meal, as food reduces its absorption. Take it at the same time every day to maintain a consistent level in your body, and keep all scheduled appointments with your specialist for blood tests, as chronic hepatitis B treatment requires regular monitoring of your liver, kidney function, and HBV DNA level.

Dosage

The usual dose of Baraclude 0.5mg Tablet for adults who have not previously been treated with a nucleoside analogue is 0.5mg once daily. Your specialist may prescribe a higher dose (1mg) if you have previously been treated with lamivudine, have detectable HBV DNA on lamivudine therapy, or have decompensated liver disease, and may adjust the dose if you have reduced kidney function. Do not change your dose without your specialist’s guidance, and never stop this medicine on your own – stopping treatment can cause a severe flare-up of hepatitis.

Storage Instructions

Store below 30°C in a dry place, away from direct sunlight and out of reach of children.

Side Effects

  • Headache
  • Fatigue
  • Dizziness
  • Nausea
  • Diarrhoea
  • Trouble sleeping (insomnia)
  • Increased liver enzymes (as observed in blood tests)

Contraindications

  • Known hypersensitivity to entecavir or any ingredient in this product
  • Use as the sole treatment in patients co-infected with HIV who are not also receiving effective antiretroviral therapy, due to the risk of HIV developing resistance
  • Should not be stopped abruptly without specialist supervision, as this can trigger a severe, potentially life-threatening flare of hepatitis

Drug / Food Interactions

  • Entecavir has a low potential for interactions since it is mainly eliminated unchanged by the kidneys, but other medicines that affect kidney function may alter its clearance
  • Concurrent use of other nephrotoxic medicines should be discussed with your specialist, as combined kidney effects may need closer monitoring
  • Your specialist will screen for HIV before starting treatment, since entecavir alone is not adequate therapy for HIV infection
  • Inform your doctor of all medicines and supplements you are taking, as your entecavir dose may need review

Quick Tips

  • Never stop this medicine without your specialist’s guidance, even if you feel well – stopping can cause a serious hepatitis flare
  • Attend all scheduled blood tests to monitor your liver function, kidney function, and HBV DNA level
  • Take this medicine on an empty stomach at the same time each day for consistent absorption
  • Seek immediate medical attention for unusual muscle pain, breathing difficulty, or worsening jaundice

Ingredients / Active Ingredients

  • Entecavir 0.5mg

Safety Advice

Pregnancy

Safe If Prescribed

This medicine should only be used during pregnancy if prescribed by a doctor after careful evaluation.

Breastfeeding

Limited Data

Limited data on excretion in breast milk. Consult a doctor before use.

Kidney

Use With Care

Use cautiously. Dose adjustment or monitoring may be required.

Liver

Use With Care

Use cautiously. Liver function monitoring may be required.

Alcohol

Not Advisable

It is not advisable to consume alcohol while taking this medicine.

Driving

Use With Care

Use caution while driving until you know how this medicine affects you.

Frequently Asked Questions

Product Specifications

BrandDKSH
ManufacturerBristol Myers Squibb
ClassificationPrescription medicine
Ingredients / Active IngredientsEntecavir
Pack Size30s
Shelf LifeUse this product before the expiry date stated on the packaging. Do not use the medicine if the expiry date has passed.

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