Binafine Cream

Binafine Cream is a topical antifungal cream whose active ingredient is terbinafine hydrochloride, an allylamine antifungal. The cream is white and smooth, and is applied thinly to the skin surface. It is an external preparation that is sold over the counter.

Terbinafine acts on the fungal cell membrane by interfering with an enzyme (squalene epoxidase) involved in building ergosterol, a key component of fungal cell walls. Because the cream works at the skin surface and very little is absorbed into the bloodstream, it is unlikely to cause the systemic side effects seen with oral antifungal tablets. The cream base contains excipients that help it spread smoothly and stay on the skin.

Binafine Cream is available through DoctorOnCall for delivery in Malaysia and Singapore. Customers should read the leaflet and apply it only to skin as directed, washing their hands after use. Please speak to a pharmacist if you are pregnant, breastfeeding, giving it to a child, or already using other creams on the same area.

For external use only. Follow the directions on the pack or the advice of a doctor or pharmacist.

1. Wash and thoroughly dry the skin area, including between the toes or skin folds, before applying.
2. Apply a thin layer of cream to the affected area and a little of the surrounding skin, then rub in gently.
3. Wash your hands after each application, unless the hands are the area being treated.
4. Keep the affected area dry and wear clean, breathable clothing or socks, changing them daily.

Do not apply to the eyes, mouth, inside of the nose or on open wounds. Do not cover with airtight dressings unless told to do so.

Adults: Apply a thin layer once or twice daily, as stated on the leaflet. The length of application depends on the area, and is commonly one to two weeks for the usual skin sites, and continued for the period stated on the leaflet even if the skin appears to have cleared.

Children under 12 years: Not recommended unless advised by a doctor.

Missed application: Apply as soon as you remember, unless it is almost time for the next application. Do not apply extra.

See a doctor if there is no improvement after the period on the leaflet, or if the skin worsens.

Store below the temperature stated on the pack, away from heat and direct sunlight. Keep the tube tightly closed and keep out of the reach of children. Do not freeze.

• Known hypersensitivity to terbinafine or any other ingredient in the cream.
• Application to the eyes, mouth, nose or other mucous membranes.
• Application to broken or infected skin not assessed by a doctor.
• Children under 12 years unless advised by a doctor.
• Use under airtight dressings unless advised by a doctor.

• No significant interactions with oral medicines are expected, as very little terbinafine is absorbed from the skin.
• Do not apply other creams, ointments or lotions to the same skin area at the same time without advice.
• Tell your doctor or pharmacist if you are also taking terbinafine tablets or other antifungal medicines.
• No known food interactions.
• Avoid applying with skin-irritating products such as strong soaps or alcohol-based lotions on the same area.

• Keep the skin clean and completely dry before each application.
• Continue applying for the full period on the leaflet, even if the skin looks better.
• Change socks and underwear daily and wear breathable fabrics.
• Do not share towels, socks, footwear or the cream with other people.
• Wash your hands after application to avoid spreading the infection.
• Do not use on the face unless a doctor has advised it.

Precautions: For external use only. Avoid the eyes, mouth and mucous membranes, and do not apply to open wounds. Wash your hands after use. Not recommended for children under 12 years without medical advice. Speak to a pharmacist before use in pregnancy or breastfeeding, and avoid sharing towels or footwear.

When to See a Doctor or Pharmacist: See a doctor or pharmacist if the skin does not improve after the period on the leaflet, worsens, spreads or keeps returning, or if you develop a rash, blistering, swelling or severe irritation. Seek medical advice promptly if you have diabetes or weakened immunity, or if the affected area involves the nails or scalp.