Cholib 145/20mg Tablet

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Brand Abbott
Manufacturer Abbott
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Dr. Mohd Izzat Amir Bin Awang
Reviewed byDr. Mohd Izzat Amir Bin AwangDoctor of Medicine (MD), University of Mansoura - Manchester
Dr. Adeline Carol Peters
Written byDr. Adeline Carol PetersBachelor of Medicine and Bachelor of Surgery (MBBS) — Manipal Academy of Higher Education (MAHE)

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Overview

Cholib 145/20mg Tablet is a prescription-only medicine (POM) that contains Fenofibrate 145mg and Simvastatin 20mg. It is supplied as a tablet and is dispensed in Malaysia only against a valid prescription issued by a registered doctor.

Under Malaysian rules for prescription medicines, this page carries product, safety and handling information only. Your doctor or pharmacist will explain whether this medicine is suitable for you, the dose you should take, and how long you should take it.

On DoctorOnCall, Cholib 145/20mg Tablet is reviewed by a licensed doctor through an online consultation and dispensed by a registered pharmacist before delivery. Always follow the instructions on your prescription label and the package insert supplied with the product, and do not share this medicine with anyone else.

Directions for Use

Take Cholib 145/20mg Tablet in the evening with a meal, as food improves the absorption of fenofibrate. Swallow the tablet whole with water; do not crush or chew it. Try to take it at the same time each evening to build a consistent routine.

Dosage

The usual dose of Cholib 145/20mg Tablet is one tablet taken once daily in the evening. Your doctor will confirm the correct dose for you and will monitor your cholesterol, liver function, and muscle-related symptoms periodically with blood tests while you are on this combination.

Storage Instructions

Store below 30°C in a dry place, away from direct sunlight and out of reach of children.

Side Effects

  • Headache
  • Stomach pain
  • Nausea or vomiting
  • Muscle pain or weakness
  • Tiredness
  • Skin rash or itching
  • Mild diarrhea

Contraindications

  • Known hypersensitivity to fenofibrate, simvastatin, or any ingredient in this product
  • Active liver disease or unexplained persistent elevation of liver enzymes
  • Severe kidney impairment
  • Known gallbladder disease
  • Pregnancy and breastfeeding
  • Concomitant use with potent CYP3A4 inhibitors (e.g. itraconazole, ketoconazole, HIV protease inhibitors) or with ciclosporin or gemfibrozil, due to a significantly increased risk of myopathy and rhabdomyolysis

Drug / Food Interactions

  • Potent CYP3A4 inhibitors (e.g. itraconazole, ketoconazole, clarithromycin, HIV protease inhibitors) significantly increase the risk of muscle-related side effects and must be avoided
  • Other statins, fibrates, or ciclosporin further increase the risk of myopathy when combined
  • Warfarin’s blood-thinning effect may be enhanced, requiring closer monitoring of clotting tests
  • Large amounts of grapefruit juice can increase simvastatin levels in the blood

Quick Tips

  • Report any unexplained muscle pain, tenderness, or weakness to your doctor promptly
  • Attend all scheduled blood tests to monitor your cholesterol, liver function, and muscle enzymes
  • Avoid large amounts of grapefruit juice while taking this medicine
  • Take this medicine in the evening with food for the best absorption of fenofibrate

Ingredients / Active Ingredients

  • Fenofibrate 145mg
  • Simvastatin 20mg

Safety Advice

Pregnancy

Safe If Prescribed

This medicine should only be used during pregnancy if prescribed by a doctor after careful evaluation.

Breastfeeding

Not Safe

This medicine is not safe during breastfeeding and should be avoided.

Kidney

Use With Care

Use cautiously. Dose adjustment or monitoring may be required.

Liver

No Data

No adequate data available. Consult a doctor before use.

Alcohol

Not Advisable

It is not advisable to consume alcohol while taking this medicine.

Driving

Not Advisable

It is not advisable to drive if you experience side effects from this medicine.

Frequently Asked Questions

Product Specifications

BrandAbbott
ManufacturerAbbott
ClassificationPrescription medicine
Ingredients / Active IngredientsFenofibrate
Pack Size30s
Shelf LifeUse this product before the expiry date stated on the packaging. Do not use the medicine if the expiry date has passed.

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