Coveram 10/10mg Tablet

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Dr. Mohd Izzat Amir Bin Awang
Reviewed byDr. Mohd Izzat Amir Bin AwangDoctor of Medicine (MD), University of Mansoura - Manchester
Dr. Chong Zhan Pong
Written byDr. Chong Zhan PongDoctor of Medicine (MD), International Medical University (IMU)

Last updated:

Overview

Coveram 10/10mg Tablet is a prescription-only medicine (POM) that contains Perindopril arginine 10mg and Amlodipine 10mg. It is supplied as a tablet and is dispensed in Malaysia only against a valid prescription issued by a registered doctor.

Under Malaysian rules for prescription medicines, this page carries product, safety and handling information only. Your doctor or pharmacist will explain whether this medicine is suitable for you, the dose you should take, and how long you should take it.

On DoctorOnCall, Coveram 10/10mg Tablet is reviewed by a licensed doctor through an online consultation and dispensed by a registered pharmacist before delivery. Always follow the instructions on your prescription label and the package insert supplied with the product, and do not share this medicine with anyone else.

Directions for Use

Take Coveram 10/10mg Tablet once daily in the morning, before breakfast, as food may reduce absorption of the perindopril component. Swallow the tablet whole with a glass of water. Do not stop taking this medicine suddenly without consulting your doctor, even if you feel well, as blood pressure control needs to be continuous.

Dosage

Coveram 10/10mg Tablet is usually taken as one tablet once daily in the morning. Your doctor will determine the appropriate strength for you based on your blood pressure response and whether you have previously been controlled on perindopril or amlodipine alone. Always take this medicine exactly as prescribed.

Storage Instructions

Store below 30°C in a dry place, away from direct sunlight and out of reach of children.

Side Effects

  • Headache
  • Dizziness or lightheadedness
  • Swelling of the ankles or feet
  • Fatigue
  • Flushing (warmth or redness in face/skin)
  • Nausea

Contraindications

  • Known hypersensitivity to perindopril, amlodipine, other dihydropyridine calcium channel blockers, or any other ACE inhibitor
  • Previous history of angioedema related to ACE inhibitor use
  • Severe hypotension or cardiogenic shock
  • Severe aortic stenosis or unstable angina
  • Pregnancy and breastfeeding

Drug / Food Interactions

  • Potassium supplements or potassium-sparing diuretics may increase the risk of high blood potassium
  • Grapefruit and grapefruit juice can increase amlodipine blood levels and the risk of side effects
  • Simvastatin doses above 20mg daily should be avoided with amlodipine due to increased risk of muscle-related side effects
  • NSAIDs (e.g. ibuprofen) may reduce the blood-pressure-lowering effect and affect kidney function

Quick Tips

  • Take at the same time each morning, before breakfast, to build a consistent routine
  • Rise slowly from sitting or lying down to reduce dizziness, especially when starting treatment
  • Report new or worsening ankle swelling to your doctor
  • Avoid grapefruit or grapefruit juice while taking this medicine

Ingredients / Active Ingredients

  • Perindopril arginine 10mg
  • Amlodipine 10mg

Safety Advice

Pregnancy

Use With Care

This medicine should be used cautiously during pregnancy. Monitoring may be required.

Breastfeeding

Use With Care

Use with caution. Monitor infant for potential adverse reactions.

Kidney

Generally Safe

Generally safe, but caution may be required in some patients.

Liver

Use With Care

Use cautiously. Liver function monitoring may be required.

Alcohol

Not Advisable

It is not advisable to consume alcohol while taking this medicine.

Driving

Use With Care

Use caution while driving until you know how this medicine affects you.

Frequently Asked Questions

Product Specifications

BrandServier
ClassificationPrescription medicine
Ingredients / Active IngredientsAmlodipine
Pack Size30s
Shelf LifeUse this product before the expiry date stated on the packaging. Do not use the medicine if the expiry date has passed.

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