Covinace 8mg Tablet
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Prescription Required
Overview
Covinace 8mg Tablet contains Perindopril 8mg, an angiotensin-converting enzyme (ACE) inhibitor used to treat high blood pressure (hypertension). The perindopril salt form used in Covinace follows its own dosing scale that is distinct from the perindopril arginine formulation used in some other perindopril-containing brands, so doses between different brands are not interchangeable milligram-for-milligram without your doctor’s guidance.
Perindopril works by blocking the enzyme that converts angiotensin I into angiotensin II, a hormone that narrows blood vessels and triggers sodium and water retention. By reducing angiotensin II formation, perindopril allows blood vessels to relax, lowering blood pressure and easing the heart’s workload.
How it Works
Perindopril inhibits angiotensin-converting enzyme (ACE), reducing the formation of angiotensin II and lowering aldosterone secretion. This relaxes and widens blood vessels and reduces sodium/water retention, lowering blood pressure. ACE inhibition also increases levels of bradykinin, a substance that contributes to the characteristic dry cough some patients experience with this drug class.
Directions for Use
Take Covinace 8mg Tablet once daily in the morning, before breakfast, as food may reduce its absorption. Swallow the tablet whole with a glass of water. Do not stop taking this medicine suddenly without consulting your doctor, even if you feel well, as blood pressure control needs to be continuous.
Dosage
The usual starting dose of Covinace 8mg Tablet is taken once daily in the morning, and your doctor may adjust it gradually based on your blood pressure response, up to the maximum dose considered appropriate for you. Always take this medicine exactly as prescribed, and do not adjust the dose yourself.
Shelf Life
Use this product before the expiry date stated on the packaging. Do not use the medicine if the expiry date has passed.
Storage Instructions
Store below 30°C in a dry place, away from direct sunlight and out of reach of children.
Side Effects
- Dizziness or lightheadedness
- Cough
- Headache
- Tiredness or fatigue
- Nausea
- Low blood pressure
- Rash or skin irritation
- Elevated potassium levels
- Changes in kidney function
Contraindications
- Known hypersensitivity to perindopril or any other ACE inhibitor
- Previous history of angioedema related to ACE inhibitor use
- Pregnancy and breastfeeding
- Concomitant use with aliskiren in patients with diabetes or kidney impairment
- Bilateral renal artery stenosis or renal artery stenosis in a single functioning kidney
Drug / Food Interactions
- Potassium supplements or potassium-sparing diuretics may increase the risk of high blood potassium
- NSAIDs (e.g. ibuprofen) may reduce the blood-pressure-lowering effect and affect kidney function
- Lithium levels may increase when combined with perindopril, raising the risk of lithium toxicity
- Other antihypertensive medicines or diuretics may increase the risk of low blood pressure, particularly after the first dose
Quick Tips
- Take at the same time each morning, before breakfast, to build a consistent routine
- Rise slowly from sitting or lying down to reduce dizziness, especially when starting treatment
- Report a persistent dry cough to your doctor rather than stopping the medicine yourself
- Monitor your blood pressure regularly as advised by your doctor
Frequently Asked Questions
What is Covinace 8mg Tablet used for?
Covinace 8mg Tablet is used to treat high blood pressure (hypertension). Your doctor will confirm the specific reason it has been prescribed for you.
Why do I have a dry cough since starting this medicine?
A persistent dry cough is a well-recognised side effect of ACE inhibitors like perindopril, caused by a build-up of a substance called bradykinin. Tell your doctor if the cough is bothersome, as an alternative medicine may be considered.
Is Covinace the same as Coversyl?
Both contain perindopril, but Covinace uses a different perindopril salt form with its own dosing scale than the perindopril arginine used in Coversyl – the doses are not directly interchangeable, so always follow the specific dose prescribed for the brand you are given.
Can I stop taking this medicine if my blood pressure normalises?
No, do not stop without consulting your doctor. High blood pressure often has no symptoms, and stopping suddenly can cause your blood pressure to rise again.
What should I do if I miss a dose of Covinace 8mg Tablet?
Take the missed dose as soon as you remember, unless it is almost time for your next dose – in that case, skip the missed dose and continue your regular schedule. Do not double the dose.
Can I buy Covinace 8mg Tablet from DoctorOnCall?
Yes, Covinace 8mg Tablet is available through DoctorOnCall, a licensed online pharmacy serving our Malaysian and Singaporean customers. As this is a prescription medicine, you will need to complete an online consultation so a doctor can assess your suitability and issue a valid prescription before the order is processed. This ensures the medicine is appropriate for your condition and used under proper medical supervision, whether you are ordering from Malaysia or Singapore.
Is the medication provided by DoctorOnCall genuine and safe to use?
DoctorOnCall sources its medicines through appropriate licensed pharmacy supply channels for our Malaysian and Singaporean customers. All orders are dispensed and checked by a registered pharmacist before delivery. Always use Covinace 8mg Tablet according to your doctor’s instructions and the information provided with the product.
What payment methods does DoctorOnCall accept?
We accept payment via Online Banking, Credit Card, and e-Wallets (Boost, GrabPay) for our Malaysian and Singaporean customers, so you can choose whichever method is most convenient for you at checkout.
Does DoctorOnCall provide an installment payment plan for Covinace 8mg Tablet?
DoctorOnCall provides an installment payment plan for eligible Malaysian and Singaporean customers, where applicable. Available plans, eligibility, and terms can vary by market, so please contact DoctorOnCall Customer Service for the latest information on installment options for your order.
Is delivery free, and how much does shipping for Covinace 8mg Tablet cost?
Delivery charges may vary for our Malaysian and Singaporean customers depending on your delivery location and the applicable order terms at the time of purchase. For the most accurate and up-to-date delivery fee information, please contact DoctorOnCall Customer Service before placing your order.
How long does delivery take for Covinace 8mg Tablet?
Our Malaysian customers can generally expect delivery within 3-5 working days, while our Singaporean customers generally receive their orders within 5-7 working days. These are expected timeframes rather than guarantees, and actual delivery time may vary depending on your delivery location, order processing time, courier operations, and whether the order falls on a weekend or public holiday.
What is DoctorOnCall’s shipping, return, or cancellation policy for Covinace 8mg Tablet?
Shipping, return, and cancellation terms may vary for our Malaysian and Singaporean customers depending on the product and your order details. Please refer to DoctorOnCall’s Shipping & Delivery Policy and Return, Refund & Exchange Policy, or contact Customer Service, for the specific terms that apply to your order.
Ingredients / Active Ingredients
- Perindopril 8mg
Safety Advice
Pregnancy
Use during pregnancy is generally not recommended unless absolutely necessary.
Breastfeeding
Use with caution. Monitor infant for potential adverse reactions.
Kidney
Use cautiously. Dose adjustment or monitoring may be required.
Liver
Use cautiously. Liver function monitoring may be required.
Alcohol
It is not advisable to consume alcohol while taking this medicine.
Driving
It is not advisable to drive if you experience side effects from this medicine.
Medical Review
