Cozaar XQ 5/50mg Tablet
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Overview
Cozaar XQ 5/50mg Tablet is a fixed-dose combination containing amlodipine 5mg and losartan 50mg, used to treat high blood pressure (hypertension) in patients whose blood pressure is not adequately controlled on either medicine alone.
Amlodipine is a calcium channel blocker that relaxes and widens blood vessels by reducing calcium entry into vascular smooth muscle, while losartan is an angiotensin II receptor blocker (ARB) that blocks a hormone that narrows blood vessels; combined, they lower blood pressure through two complementary mechanisms.
How it Works
Amlodipine blocks L-type calcium channels in vascular smooth muscle, reducing vasoconstriction, while losartan blocks the AT1 receptor to prevent angiotensin II from narrowing blood vessels and promoting sodium/water retention. Together, the two mechanisms produce a greater blood-pressure-lowering effect than either medicine used alone.
Directions for Use
Take Cozaar XQ 5/50mg Tablet at about the same time every day, with or without food. Swallow the tablet whole with a glass of water. Do not stop taking this medicine suddenly without consulting your doctor, even if you feel well, as blood pressure control needs to be continuous.
Dosage
Cozaar XQ 5/50mg Tablet is usually taken once daily as prescribed by your doctor, who will have determined this specific combination and strength based on your blood pressure response to amlodipine and/or losartan individually. Do not adjust the dose without your doctor’s advice.
Shelf Life
Use this product before the expiry date stated on the packaging. Do not use the medicine if the expiry date has passed.
Storage Instructions
Store below 30°C in a dry place, away from direct sunlight and out of reach of children.
Side Effects
- Headache
- Dizziness or lightheadedness
- Swelling of the ankles or feet
- Fatigue
- Flushing (warmth or redness in face/skin)
- Nausea
Contraindications
- Known hypersensitivity to amlodipine, losartan, other dihydropyridine calcium channel blockers, or any ingredient in this product
- Pregnancy (can harm the developing baby, especially in the second and third trimester)
- Severe hypotension, cardiogenic shock, or severe aortic stenosis
- Concomitant use with aliskiren in patients with diabetes or kidney impairment
Drug / Food Interactions
- Strong CYP3A4 inhibitors (e.g. ketoconazole, itraconazole, ritonavir) can raise amlodipine blood levels
- Potassium supplements or potassium-sparing diuretics may increase the risk of high blood potassium from the losartan component
- NSAIDs (e.g. ibuprofen) may reduce the blood-pressure-lowering effect and affect kidney function
- Grapefruit or grapefruit juice may increase amlodipine blood levels and should be avoided
Quick Tips
- Take at the same time each day to build a consistent routine
- Monitor your blood pressure regularly as advised by your doctor
- Rise slowly from sitting or lying down to reduce dizziness
- Report new or worsening ankle swelling to your doctor
Frequently Asked Questions
What is Cozaar XQ 5/50mg Tablet used for?
Cozaar XQ 5/50mg Tablet is used to treat high blood pressure that is not adequately controlled by amlodipine or losartan alone, combining two complementary blood-pressure-lowering mechanisms in one tablet.
Why has my doctor prescribed a combination tablet instead of two separate tablets?
A combination tablet like this one can simplify your treatment routine and improve adherence, while still delivering the individually-titrated doses of amlodipine and losartan your doctor has determined you need.
Can I stop taking this medicine if my blood pressure normalises?
No, do not stop without consulting your doctor. High blood pressure often has no symptoms, and stopping suddenly can cause your blood pressure to rise again.
Can I take this medicine if I am pregnant?
This medicine should not be used during pregnancy as the losartan component can harm the developing baby. Speak to your doctor immediately if you are pregnant, think you may be pregnant, or are planning to become pregnant.
What should I do if I miss a dose of Cozaar XQ 5/50mg Tablet?
Take the missed dose as soon as you remember, unless it is almost time for your next dose – in that case, skip the missed dose and continue your regular schedule. Do not double the dose.
Can I buy Cozaar XQ 5/50mg Tablet from DoctorOnCall?
Yes, Cozaar XQ 5/50mg Tablet is available through DoctorOnCall, a licensed online pharmacy serving our Malaysian and Singaporean customers. As this is a prescription medicine, you will need to complete an online consultation so a doctor can assess your suitability and issue a valid prescription before the order is processed. This ensures the medicine is appropriate for your condition and used under proper medical supervision, whether you are ordering from Malaysia or Singapore.
Is the medication provided by DoctorOnCall genuine and safe to use?
DoctorOnCall sources its medicines through appropriate licensed pharmacy supply channels for our Malaysian and Singaporean customers. All orders are dispensed and checked by a registered pharmacist before delivery. Always use Cozaar XQ 5/50mg Tablet according to your doctor’s instructions and the information provided with the product.
What payment methods does DoctorOnCall accept?
We accept payment via Online Banking, Credit Card, and e-Wallets (Boost, GrabPay) for our Malaysian and Singaporean customers, so you can choose whichever method is most convenient for you at checkout.
Does DoctorOnCall provide an installment payment plan for Cozaar XQ 5/50mg Tablet?
DoctorOnCall provides an installment payment plan for eligible Malaysian and Singaporean customers, where applicable. Available plans, eligibility, and terms can vary by market, so please contact DoctorOnCall Customer Service for the latest information on installment options for your order.
Is delivery free, and how much does shipping for Cozaar XQ 5/50mg Tablet cost?
Delivery charges may vary for our Malaysian and Singaporean customers depending on your delivery location and the applicable order terms at the time of purchase. For the most accurate and up-to-date delivery fee information, please contact DoctorOnCall Customer Service before placing your order.
How long does delivery take for Cozaar XQ 5/50mg Tablet?
Our Malaysian customers can generally expect delivery within 3-5 working days, while our Singaporean customers generally receive their orders within 5-7 working days. These are expected timeframes rather than guarantees, and actual delivery time may vary depending on your delivery location, order processing time, courier operations, and whether the order falls on a weekend or public holiday.
What is DoctorOnCall’s shipping, return, or cancellation policy for Cozaar XQ 5/50mg Tablet?
Shipping, return, and cancellation terms may vary for our Malaysian and Singaporean customers depending on the product and your order details. Please refer to DoctorOnCall’s Shipping & Delivery Policy and Return, Refund & Exchange Policy, or contact Customer Service, for the specific terms that apply to your order.
Ingredients / Active Ingredients
- Amlodipine 5mg (as amlodipine besilate)
- Losartan potassium 50mg
Safety Advice
Pregnancy
This medicine should be used cautiously during pregnancy. Monitoring may be required.
Breastfeeding
Use with caution. Monitor infant for potential adverse reactions.
Kidney
Generally safe, but caution may be required in some patients.
Liver
Use cautiously. Liver function monitoring may be required.
Alcohol
It is not advisable to consume alcohol while taking this medicine.
Driving
Use caution while driving until you know how this medicine affects you.
Medical Review
