Written byDr. Adeline Carol PetersBachelor of Medicine and Bachelor of Surgery (MBBS) — Manipal Academy of Higher Education (MAHE)
Last updated:
Overview
Difflam 0.15% Solution is supplied as a solution, with Benzydamine Hydrochloride 0.15% w/v. It is supplied in a pack size of 100ml.
No prescription is required for this product, as it is a non-prescription medicine. This page is limited to product, safety and handling information.
If you would like guidance before buying, you can speak to a doctor or pharmacist through an online consultation on DoctorOnCall. Orders are dispensed by a registered pharmacist and delivered to your address.
Directions for Use
Rinse or gargle with 15 ml of undiluted solution (or as directed) for 15-30 seconds, then spit out; repeat every 1.5-3 hours as needed, up to 3 times a day, or as advised by a pharmacist or doctor; do not swallow the solution.
Storage Instructions
Store below 25°C in a cool, dry place away from direct sunlight; keep out of reach of children; do not freeze.
Side Effects
Benzydamine + Chlorhexidine Gluconate
Mild burning or stinging sensation in the mouth
Dry mouth or taste disturbance
Mouth irritation or numbness
Discoloration of teeth or tongue (temporary)
Allergic reaction such as rash or mouth ulcers (rare)
Benzydamine
Mouth or throat irritation
Numbness or tingling sensation
Dry mouth
Skin rash (for topical formulations)
Allergic reactions (rare)
Contraindications
Known hypersensitivity to benzydamine hydrochloride or any other ingredient in the solution
Children under 12 years unless advised by a doctor
Not for swallowing/ingestion
Drug / Food Interactions
No clinically significant systemic drug interactions reported due to minimal systemic absorption with topical/gargle use
Avoid using simultaneously with other oral antiseptic/anti-inflammatory mouth rinses without medical advice
Inform your pharmacist if you are using other mouth or throat medications concurrently
Quick Tips
Do not swallow; spit out after gargling
Avoid eating or drinking immediately after use to allow the solution to act
Dilute with water if stinging occurs, if advised by a pharmacist
Seek medical advice if sore throat persists beyond 3 days or worsens with fever
This medicine should be used cautiously during pregnancy. Monitoring may be required.
Breastfeeding
Use With Care
Use with caution. Monitor infant for potential adverse reactions.
Kidney
Generally Safe
Generally safe, but caution may be required in some patients.
Liver
Generally Safe
Generally safe, but caution may be required in some patients.
Alcohol
Use With Care
Caution is advised when consuming alcohol with this medicine.
Driving
Use With Care
Use caution while driving until you know how this medicine affects you.
Benzydamine
Pregnancy
Safe If Prescribed
This medicine should only be used during pregnancy if prescribed by a doctor after careful evaluation.
Breastfeeding
Safe If Prescribed
Use during breastfeeding should only be done if prescribed and monitored by a doctor.
Kidney
Generally Safe
Generally safe, but caution may be required in some patients.
Liver
No Data
No adequate data available. Consult a doctor before use.
Alcohol
No Data
No data is available regarding the interaction of alcohol with this medicine.
Driving
Generally Safe
This medicine is generally safe and should not impair your driving ability.
Relevant Information
Difflam 0.15% Solution is intended for short-term symptomatic relief; if symptoms of sore throat or mouth pain persist beyond a few days, are accompanied by high fever, difficulty swallowing, or breathing difficulty, seek prompt medical attention. It should be used as an adjunct to good oral hygiene practices rather than a substitute for dental or medical care when an underlying infection is suspected.
Frequently Asked Questions
No. Difflam 0.15% Solution is a non-prescription product and can be ordered without a prescription. It is still dispensed by a registered pharmacist on DoctorOnCall.
Difflam 0.15% Solution is a solution containing Benzydamine Hydrochloride 0.15% w/v. The full ingredient list is shown in the Composition or Ingredients section on this page and on the product packaging.
It is supplied in a pack size of 100ml. Choose the pack size you need from the options shown on this page before adding the item to your cart.
This page is limited to product, safety and handling information in line with Malaysian rules on medicine information. If you want advice on whether this product suits you, book an online consultation with a doctor or pharmacist on DoctorOnCall.
Follow the instructions printed on the label and in the leaflet supplied with the pack, and do not exceed the stated amount or duration. Handling steps are set out in the Directions for Use section on this page.
Yes. DoctorOnCall offers online consultations with licensed doctors and registered pharmacists, so you can ask about this product, your existing medicines, or anything on the label before you place an order.
Store below 25°C in a cool, dry place away from direct sunlight; keep out of reach of children; do not freeze. Keep it in its original pack and do not use it after the expiry date printed on the packaging.
Stop using the product and speak to a doctor or pharmacist about any reaction that concerns you. Seek medical care immediately for signs of a severe reaction such as difficulty breathing, swelling of the face, lips or throat, or a widespread rash. Reported reactions are listed in the Side Effects section on this page.
Within Malaysia, standard delivery takes 3 to 5 working days. Same-day delivery is available in the Klang Valley for orders placed before 12pm; orders placed after 12pm arrive by the end of the next day.
Orders to Singapore are sent as international deliveries and take 5 to 9 working days. A lump-sum shipping and handling fee applies to every overseas delivery and is shown at checkout.
Customers in Malaysia can pay by FPX online banking, credit or debit card (Visa and Mastercard), and supported e-wallets including Touch ‘n Go eWallet, GrabPay and ShopeePay.
FPX and local e-wallets are tied to Malaysian bank and wallet accounts, so if your delivery address is in Singapore, use the payment options displayed at checkout for that address rather than assuming the same list applies.
Yes. DoctorOnCall ships to Singapore as an international order dispatched from Malaysia, arriving in 5 to 9 working days with a lump-sum shipping and handling fee.
Singapore’s Health Sciences Authority (HSA) allows personal imports of up to three months’ supply of a medicine for your own use or an immediate family member’s, as long as it contains no controlled drugs, psychotropic substances or prohibited items. Keep the product in its original labelled packaging and keep a copy of your prescription or doctor’s letter with it. Quantities above three months’ supply, and medicines containing controlled substances, require prior HSA approval.
Products listed on DoctorOnCall are registered with Malaysia’s Ministry of Health for supply in Malaysia, and each pack carries its MAL registration number.
An order delivered to Singapore arrives as a personal import of a Malaysia-registered product; HSA product registration is not required for personal-use quantities, but it is also not the same as a product registered for sale in Singapore. If you need a locally registered Singapore product, buy it from a pharmacy in Singapore.
DoctorOnCall’s customer care team handles order, delivery and product queries through the contact channels on the site, including WhatsApp and the online help centre.
For deliveries to Singapore, allow more time before chasing an order than you would for a local Malaysian delivery, as the parcel passes through customs clearance and tracking updates can appear later in the journey.
Adults and children over 12 years: gargle/rinse with 15 ml undiluted, 2-3 times daily; not recommended for children under 12 years unless directed by a doctor; do not exceed the recommended frequency.
Shelf Life
Typically 2-3 years from date of manufacture when unopened; check the expiry date printed on the packaging and do not use beyond that date.
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Important Medical Information
💊 Recommended Dosage:
Adults and children over 12 years: gargle/rinse with 15 ml undiluted, 2-3 times daily; not recommended for children under 12 years unless directed by a doctor; do not exceed the recommended frequency.
🛑 Contraindications (Do not use if):
Known hypersensitivity to benzydamine hydrochloride or any other ingredient in the solution
Children under 12 years unless advised by a doctor
Not for swallowing/ingestion
If you are unsure, please chat with us or consult your doctor.
⚠️ Common Side Effects:
Benzydamine + Chlorhexidine Gluconate:
Mild burning or stinging sensation in the mouth
Dry mouth or taste disturbance
Mouth irritation or numbness
Discoloration of teeth or tongue (temporary)
Allergic reaction such as rash or mouth ulcers (rare)
Benzydamine:
Mouth or throat irritation
Numbness or tingling sensation
Dry mouth
Skin rash (for topical formulations)
Allergic reactions (rare)
Stop taking this medication immediately and consult your doctor if you experience severe allergic reactions or side effects.
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IMPORTANT: Unsure? Chat with our pharmacists (Mon - Sat, 9:00am - 6:00pm) before buying.