Duac Once Daily Gel

Rx
Brand GSK
Manufacturer GSK
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  • FDA Approved
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Dr. Mohd Izzat Amir Bin Awang
Reviewed byDr. Mohd Izzat Amir Bin AwangDoctor of Medicine (MD), University of Mansoura - Manchester
Dr. Adeline Carol Peters
Written byDr. Adeline Carol PetersBachelor of Medicine and Bachelor of Surgery (MBBS) — Manipal Academy of Higher Education (MAHE)

Last updated:

Overview

Duac Once Daily Gel is a prescription-only medicine (POM) that contains Clindamycin phosphate and benzoyl peroxide 1%/5%. It is supplied as a gel and is dispensed in Malaysia only against a valid prescription issued by a registered doctor.

Under Malaysian rules for prescription medicines, this page carries product, safety and handling information only. Your doctor or pharmacist will explain whether this medicine is suitable for you, the dose you should take, and how long you should take it.

On DoctorOnCall, Duac Once Daily Gel is reviewed by a licensed doctor through an online consultation and dispensed by a registered pharmacist before delivery. Always follow the instructions on your prescription label and the package insert supplied with the product, and do not share this medicine with anyone else.

Directions for Use

Wash and dry the affected area gently before applying a thin layer of {title_en}, avoiding the eyes, lips, and mucous membranes. Wash your hands after application, and allow the gel to dry before applying any other skincare products or makeup. Benzoyl peroxide can bleach coloured fabrics, towels, and bedding, so use white linens where possible and allow the gel to fully absorb before contact with clothing.

Dosage

Duac Once Daily Gel is usually applied once daily to the affected areas of the face, in the evening, after cleansing. Your doctor or pharmacist will advise on the amount to use and how long treatment should continue, as visible improvement in acne typically takes several weeks.

Storage Instructions

Store below 30°C in a dry place, away from direct sunlight and out of reach of children.

Side Effects

  • Dryness or peeling of the skin
  • Redness or irritation
  • Burning or stinging sensation
  • Skin flaking
  • Mild allergic reactions such as itching or rash

Contraindications

  • Known hypersensitivity to clindamycin, lincomycin, benzoyl peroxide, or any ingredient in this product
  • History of antibiotic-associated colitis (e.g. with clindamycin or lincomycin)
  • Broken, sunburnt, or severely irritated skin
  • Avoid use around the eyes, mouth, nostrils, and mucous membranes

Drug / Food Interactions

  • Avoid using other topical acne products (e.g. retinoids, other peeling or exfoliating agents) at the same time without your doctor’s advice, as this increases skin irritation
  • Other topical antibiotics should generally not be applied to the same area simultaneously
  • Photosensitising medicines or products may add to the sun-sensitivity risk of this gel

Quick Tips

  • Apply once daily to clean, dry skin, usually in the evening
  • Start with sparing use if your skin is sensitive, to reduce initial dryness or peeling
  • Use a broad-spectrum sunscreen daily, as this gel can increase sun sensitivity
  • Use white towels, pillowcases, and clothing, as benzoyl peroxide can bleach coloured fabric
  • Give it time – visible improvement in acne usually takes several weeks of consistent use
  • Stop and contact your doctor if you develop severe or persistent diarrhoea

Ingredients / Active Ingredients

  • Clindamycin phosphate and benzoyl peroxide 1%/5%

Safety Advice

Pregnancy

Generally Safe

This medicine is generally safe during pregnancy, though minor risks may exist in rare cases.

Breastfeeding

Generally Safe

This medicine is generally safe during breastfeeding with minimal risk to the infant.

Kidney

No Data

No adequate data available. Consult a doctor before use.

Liver

Limited Data

Limited data available in liver disease patients.

Alcohol

Not Advisable

It is not advisable to consume alcohol while taking this medicine.

Driving

Generally Safe

This medicine is generally safe and should not impair your driving ability.

Frequently Asked Questions

Product Specifications

BrandGSK
ManufacturerGSK
ClassificationPrescription medicine
Ingredients / Active IngredientsBenzoyl Peroxide
Weight25g
Shelf LifeUse this product before the expiry date stated on the packaging. Do not use the medicine if the expiry date has passed.

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