Epiduo Gel
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Prescription Required
Overview
Epiduo Gel is a prescription-only medicine (POM) that contains Adapalene 0.1% and Benzoyl peroxide 2.5%. It is supplied as a gel and is dispensed in Malaysia only against a valid prescription issued by a registered doctor.
Under Malaysian rules for prescription medicines, this page carries product, safety and handling information only. Your doctor or pharmacist will explain whether this medicine is suitable for you, the dose you should take, and how long you should take it.
On DoctorOnCall, Epiduo Gel is reviewed by a licensed doctor through an online consultation and dispensed by a registered pharmacist before delivery. Always follow the instructions on your prescription label and the package insert supplied with the product, and do not share this medicine with anyone else.
Directions for Use
Wash and gently dry the affected skin before application. Apply a pea-sized amount thinly and evenly over the entire affected area (not just individual spots), avoiding the eyes, lips, and mucous membranes. Wash your hands after use. Apply a broad-spectrum sunscreen during the day, as this medicine increases your skin’s sensitivity to sunlight.
Dosage
Apply a thin layer of Epiduo Gel to the affected area once daily, usually in the evening. Your doctor may advise starting with application every other day if your skin is sensitive, before building up to once-daily use as tolerated.
Shelf Life
Use this product before the expiry date stated on the packaging. Do not use the medicine if the expiry date has passed.
Storage Instructions
Store below 30°C in a dry place, away from direct sunlight and out of reach of children.
Side Effects
- Dryness or peeling of the skin
- Redness or irritation
- Burning or stinging sensation
- Skin flaking
- Mild allergic reactions such as itching or rash
Contraindications
- Known hypersensitivity to adapalene, benzoyl peroxide, or any ingredient in this product
- Pregnancy (topical retinoids are generally avoided in pregnancy – discuss with your doctor)
- Use on eczema, sunburnt, or broken/irritated skin
- Concurrent use with other strong irritant or peeling skin products unless specifically advised by your doctor
Drug / Food Interactions
- Other topical acne treatments, retinoids, or exfoliants used at the same time may increase skin irritation – space these out or avoid combining unless advised by your doctor
- Sun exposure and sunbeds increase the risk of sunburn during treatment – always use sunscreen
- Benzoyl peroxide is an oxidising agent that can bleach hair and coloured fabric on contact – avoid contact with hair, clothing, and bedding
- Other topical products containing salicylic acid or alcohol-based astringents may worsen dryness or irritation when used together
Quick Tips
- Start with application every other night if you are new to retinoids, to help your skin build tolerance
- Moisturise regularly with a non-comedogenic moisturiser to manage dryness
- Always apply sunscreen during the day, as this medicine increases sun sensitivity
- Avoid contact with towels, pillowcases, and clothing, as benzoyl peroxide can bleach coloured fabric
- Avoid applying near the eyes, lips, and mucous membranes
- Give the medicine 8-12 weeks of consistent use for the full effect before judging results – do not stop early
Frequently Asked Questions
Is Epiduo Gel a prescription medicine?
Yes. Epiduo Gel is a prescription-only medicine (POM). It can only be supplied against a valid prescription written by a registered doctor, and it should be used only by the person named on the prescription label.
What does Epiduo Gel contain?
Epiduo Gel is supplied as a gel and contains Adapalene 0.1% and Benzoyl peroxide 2.5%. The full composition is listed in the Composition section on this page and on the product packaging.
Why is there no information here about what Epiduo Gel is for?
Malaysian rules for prescription medicines limit public product pages to product, safety and handling information. Your doctor decides whether this medicine is appropriate for you and will explain it during your consultation, and your pharmacist can answer further questions when the medicine is dispensed.
How should I take Epiduo Gel?
Follow your doctor’s instructions and the directions on the dispensing label without changing them. If anything on the label is unclear, check with your pharmacist before taking the first dose, and read the Directions for Use section on this page.
What should I do if I miss a dose?
Take it as soon as you remember, unless your next dose is nearly due. In that case skip the missed dose and carry on with your usual schedule. Never take two doses together to make up for a missed one. If you miss doses often, tell your doctor or pharmacist.
How should I store Epiduo Gel?
Store below 30°C in a dry place, away from direct sunlight and out of reach of children. Keep it in the original pack until use, and do not use it after the expiry date printed on the packaging.
What should I do if I notice side effects?
Tell your doctor or pharmacist about any reaction that concerns you, and seek medical care immediately for signs of a severe reaction such as difficulty breathing, swelling of the face, lips or throat, or a widespread rash. Reported reactions are listed in the Side Effects section on this page.
Can I stop taking Epiduo Gel on my own?
No. Speak to your doctor before stopping, pausing or changing the dose, even if you feel well or think you no longer need the medicine.
How do I get a prescription for Epiduo Gel?
Customers in Malaysia can complete an online consultation with a DoctorOnCall doctor, who decides whether a prescription is appropriate, or upload a valid prescription already issued by their own doctor.
Orders going to Singapore are dispatched from Malaysia as an international delivery, so you need to hold a valid prescription or doctor’s letter for the medicine. Check the consultation and prescription upload options shown at checkout for your delivery address before placing the order.
How long will delivery take?
Within Malaysia, standard delivery takes 3 to 5 working days. Same-day delivery is available in the Klang Valley for orders placed before 12pm; orders placed after 12pm arrive by the end of the next day.
Orders to Singapore are sent as international deliveries and take 5 to 9 working days. A lump-sum shipping and handling fee applies to every overseas delivery and is shown at checkout.
What payment methods can I use?
Customers in Malaysia can pay by FPX online banking, credit or debit card (Visa and Mastercard), and supported e-wallets including Touch ‘n Go eWallet, GrabPay and ShopeePay.
FPX and local e-wallets are tied to Malaysian bank and wallet accounts, so if your delivery address is in Singapore, use the payment options displayed at checkout for that address rather than assuming the same list applies.
Can Epiduo Gel be delivered to Singapore?
Yes. DoctorOnCall ships to Singapore as an international order dispatched from Malaysia, arriving in 5 to 9 working days with a lump-sum shipping and handling fee.
Singapore’s Health Sciences Authority (HSA) allows personal imports of up to three months’ supply of a medicine for your own use or an immediate family member’s, as long as it contains no controlled drugs, psychotropic substances or prohibited items. Keep the product in its original labelled packaging and keep a copy of your prescription or doctor’s letter with it. Quantities above three months’ supply, and medicines containing controlled substances, require prior HSA approval.
Is Epiduo Gel registered with the authorities?
Products listed on DoctorOnCall are registered with Malaysia’s Ministry of Health for supply in Malaysia, and each pack carries its MAL registration number.
An order delivered to Singapore arrives as a personal import of a Malaysia-registered product; HSA product registration is not required for personal-use quantities, but it is also not the same as a product registered for sale in Singapore. If you need a locally registered Singapore product, buy it from a pharmacy in Singapore.
Who do I contact if there is a problem with my order?
DoctorOnCall’s customer care team handles order, delivery and product queries through the contact channels on the site, including WhatsApp and the online help centre.
For deliveries to Singapore, allow more time before chasing an order than you would for a local Malaysian delivery, as the parcel passes through customs clearance and tracking updates can appear later in the journey.
Ingredients / Active Ingredients
- Adapalene 0.1%
- Benzoyl peroxide 2.5%
Safety Advice
Pregnancy
This medicine is generally safe during pregnancy, though minor risks may exist in rare cases.
Breastfeeding
This medicine is generally safe during breastfeeding with minimal risk to the infant.
Kidney
No adequate data available. Consult a doctor before use.
Liver
Limited data available in liver disease patients.
Alcohol
It is not advisable to consume alcohol while taking this medicine.
Driving
This medicine is generally safe and should not impair your driving ability.
Medical Review
