Installment Available Entresto 100mg Tablet
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Prescription Required
Currently Out of Stock No Longer Available
Prescription required. Once back in stock, a doctor will review your prescription after payment.
Overview
Entresto 100mg Tablet is a prescription-only medicine (POM) presented as a tablet, with Sacubitril 49mg and Valsartan 51mg as its active ingredient content.
This page is limited to product, safety and handling information, in line with Malaysian rules on prescription medicine information for the public. Your prescriber or pharmacist is the right source for anything beyond that, together with the leaflet inside the pack.
Through DoctorOnCall, this product is supplied after an online consultation with a licensed doctor and a valid prescription, and it is checked by a registered pharmacist before dispensing. Take it exactly as prescribed, and speak to your doctor before stopping, changing the dose, or starting any other medicine alongside it.
Directions for Use
Take Entresto 100mg Tablet twice daily, at about the same times each day, with or without food. Swallow the tablet whole with a glass of water. Do not stop or change your dose without consulting your doctor, as heart failure requires continuous treatment.
Dosage
Entresto 100mg Tablet (100mg) is typically the standard intermediate dose used during titration between the starting and target maintenance doses, as directed by your doctor. Your doctor will usually increase your dose gradually, generally every 2-4 weeks as tolerated, up to your target maintenance dose, based on your blood pressure, kidney function, and potassium levels. If you are switching from an ACE inhibitor, treatment with this medicine must not start until at least 36 hours after your last dose of the ACE inhibitor, due to an increased risk of angioedema if the two overlap.
Shelf Life
Use this product before the expiry date stated on the packaging. Do not use the medicine if the expiry date has passed.
Storage Instructions
Store below 30°C in a dry place, away from direct sunlight and out of reach of children.
Side Effects
- Dizziness or lightheadedness
- Fatigue
- Headache
- Cold or flu-like symptoms
- Diarrhea
- Back pain
- Low blood pressure
- Elevated potassium levels
Contraindications
- Known hypersensitivity to sacubitril, valsartan, or any ingredient in this product
- History of angioedema related to previous ACE inhibitor or angiotensin receptor blocker (ARB) use
- Concomitant use with an ACE inhibitor – these must never be taken together, and a washout of at least 36 hours is required when switching between the two, due to an increased risk of angioedema
- Concomitant use with aliskiren in patients with diabetes or renal impairment
- Pregnancy
Drug / Food Interactions
- ACE inhibitors must not be combined with this medicine – a 36-hour washout period is required when switching, due to the risk of angioedema
- Potassium supplements or potassium-sparing diuretics can increase the risk of high blood potassium
- NSAIDs may reduce this medicine’s effectiveness and can worsen kidney function
- Lithium levels may increase when combined with this medicine, raising the risk of lithium toxicity
Quick Tips
- Never take this medicine together with an ACE inhibitor – tell your doctor about all your current medicines before starting
- Monitor your blood pressure regularly and report dizziness or fainting to your doctor
- Attend scheduled blood tests for kidney function and potassium levels
- Rise slowly from sitting or lying down to reduce dizziness
- Seek emergency care immediately for any swelling of the face, lips, tongue, or throat, or difficulty breathing
- Do not stop this medicine abruptly without medical advice, as heart failure requires continuous treatment
Frequently Asked Questions
Is Entresto 100mg Tablet a prescription medicine?
Yes. Entresto 100mg Tablet is a prescription-only medicine (POM). It can only be supplied against a valid prescription written by a registered doctor, and it should be used only by the person named on the prescription label.
What does Entresto 100mg Tablet contain?
Entresto 100mg Tablet is supplied as a tablet and contains Sacubitril 49mg and Valsartan 51mg. The full composition is listed in the Composition section on this page and on the product packaging.
Why is there no information here about what Entresto 100mg Tablet is for?
Malaysian rules for prescription medicines limit public product pages to product, safety and handling information. Your doctor decides whether this medicine is appropriate for you and will explain it during your consultation, and your pharmacist can answer further questions when the medicine is dispensed.
How should I take Entresto 100mg Tablet?
Follow your doctor’s instructions and the directions on the dispensing label without changing them. If anything on the label is unclear, check with your pharmacist before taking the first dose, and read the Directions for Use section on this page.
What should I do if I miss a dose?
Take it as soon as you remember, unless your next dose is nearly due. In that case skip the missed dose and carry on with your usual schedule. Never take two doses together to make up for a missed one. If you miss doses often, tell your doctor or pharmacist.
How should I store Entresto 100mg Tablet?
Store below 30°C in a dry place, away from direct sunlight and out of reach of children. Keep it in the original pack until use, and do not use it after the expiry date printed on the packaging.
What should I do if I notice side effects?
Tell your doctor or pharmacist about any reaction that concerns you, and seek medical care immediately for signs of a severe reaction such as difficulty breathing, swelling of the face, lips or throat, or a widespread rash. Reported reactions are listed in the Side Effects section on this page.
Can I stop taking Entresto 100mg Tablet on my own?
No. Speak to your doctor before stopping, pausing or changing the dose, even if you feel well or think you no longer need the medicine.
How do I get a prescription for Entresto 100mg Tablet?
Customers in Malaysia can complete an online consultation with a DoctorOnCall doctor, who decides whether a prescription is appropriate, or upload a valid prescription already issued by their own doctor.
Orders going to Singapore are dispatched from Malaysia as an international delivery, so you need to hold a valid prescription or doctor’s letter for the medicine. Check the consultation and prescription upload options shown at checkout for your delivery address before placing the order.
How long will delivery take?
Within Malaysia, standard delivery takes 3 to 5 working days. Same-day delivery is available in the Klang Valley for orders placed before 12pm; orders placed after 12pm arrive by the end of the next day.
Orders to Singapore are sent as international deliveries and take 5 to 9 working days. A lump-sum shipping and handling fee applies to every overseas delivery and is shown at checkout.
What payment methods can I use?
Customers in Malaysia can pay by FPX online banking, credit or debit card (Visa and Mastercard), and supported e-wallets including Touch ‘n Go eWallet, GrabPay and ShopeePay.
FPX and local e-wallets are tied to Malaysian bank and wallet accounts, so if your delivery address is in Singapore, use the payment options displayed at checkout for that address rather than assuming the same list applies.
Can Entresto 100mg Tablet be delivered to Singapore?
Yes. DoctorOnCall ships to Singapore as an international order dispatched from Malaysia, arriving in 5 to 9 working days with a lump-sum shipping and handling fee.
Singapore’s Health Sciences Authority (HSA) allows personal imports of up to three months’ supply of a medicine for your own use or an immediate family member’s, as long as it contains no controlled drugs, psychotropic substances or prohibited items. Keep the product in its original labelled packaging and keep a copy of your prescription or doctor’s letter with it. Quantities above three months’ supply, and medicines containing controlled substances, require prior HSA approval.
Is Entresto 100mg Tablet registered with the authorities?
Products listed on DoctorOnCall are registered with Malaysia’s Ministry of Health for supply in Malaysia, and each pack carries its MAL registration number.
An order delivered to Singapore arrives as a personal import of a Malaysia-registered product; HSA product registration is not required for personal-use quantities, but it is also not the same as a product registered for sale in Singapore. If you need a locally registered Singapore product, buy it from a pharmacy in Singapore.
Who do I contact if there is a problem with my order?
DoctorOnCall’s customer care team handles order, delivery and product queries through the contact channels on the site, including WhatsApp and the online help centre.
For deliveries to Singapore, allow more time before chasing an order than you would for a local Malaysian delivery, as the parcel passes through customs clearance and tracking updates can appear later in the journey.
Ingredients / Active Ingredients
- Sacubitril 49mg
- Valsartan 51mg
Safety Advice
Pregnancy
There is no adequate data on use during pregnancy. Consult a doctor before use.
Breastfeeding
Limited data on excretion in breast milk. Consult a doctor before use.
Kidney
No adequate data available. Consult a doctor before use.
Liver
Not recommended in patients with liver disease.
Alcohol
It is not advisable to consume alcohol while taking this medicine.
Driving
It is not advisable to drive if you experience side effects from this medicine.
