Esbriet 267mg Hard Capsule
Rx- Fast Delivery
- Muslim-Friendly
- FDA Approved
- Secure Payment
Prescription Required
Overview
Esbriet 267mg Hard Capsule contains pirfenidone 267mg, an antifibrotic medicine used specifically to treat idiopathic pulmonary fibrosis (IPF) – a chronic, progressive scarring (fibrosis) of the lungs of unknown cause. It is prescribed and monitored by a respiratory specialist experienced in managing IPF.
Pirfenidone is thought to work by reducing the production and action of transforming growth factor-beta (TGF-β) and other mediators involved in fibrosis, thereby slowing the deposition of scar tissue in the lungs and the decline in lung function that occurs in IPF.
How it Works
By interfering with fibrotic signalling pathways, including those driven by TGF-β, pirfenidone is thought to reduce the excessive deposition of scar tissue (fibrosis) in the lungs that characterises IPF, helping to slow the progressive loss of lung function associated with the disease.
Directions for Use
Take Esbriet 267mg Hard Capsule capsules with food to help reduce nausea, and swallow them whole with water. Avoid grapefruit and grapefruit juice, as this may affect how the medicine is broken down in your body. Apply broad-spectrum sunscreen and wear protective clothing, and avoid direct sunlight and sunlamps/tanning beds throughout treatment, as pirfenidone can make your skin much more sensitive to sunlight.
Dosage
Esbriet 267mg Hard Capsule is typically started at a lower dose and titrated gradually over the first two to four weeks, under your specialist’s supervision, up to the target maintenance dose taken three times daily with food. Never change your own dose – any adjustment, including after side effects or missed doses, must be directed by your specialist.
Shelf Life
Use this product before the expiry date stated on the packaging. Do not use the medicine if the expiry date has passed.
Storage Instructions
Store below 30°C in a dry place, away from direct sunlight and out of reach of children.
Side Effects
- Nausea
- Fatigue
- Diarrhoea
- Loss of appetite
- Dizziness
- Skin rash or sensitivity to sunlight
- Stomach upset
- Headache
Contraindications
- Known hypersensitivity to pirfenidone or any ingredient in this product
- Severe hepatic impairment
- End-stage renal disease requiring dialysis
- Concomitant use with fluvoxamine
- Pregnancy or breastfeeding, unless specifically advised by your specialist
Drug / Food Interactions
- Fluvoxamine significantly increases pirfenidone blood levels and must not be combined with this medicine
- Ciprofloxacin may increase pirfenidone levels – your specialist may need to adjust your dose if both are needed
- Smoking may reduce this medicine’s effectiveness and should be avoided during treatment
- Grapefruit and grapefruit juice may affect how this medicine is processed by the body and should be avoided
Quick Tips
- Apply a broad-spectrum, high-SPF sunscreen daily and reapply as needed, even on cloudy days
- Wear protective clothing and a hat, and avoid prolonged direct sun exposure and tanning beds
- Attend all scheduled liver function blood tests throughout treatment
- Take each dose with food to help reduce nausea
- Never stop or change your own dose without your specialist’s guidance
- Avoid smoking during treatment, as it can reduce how well this medicine works
Frequently Asked Questions
What is Esbriet 267mg Hard Capsule used for?
Esbriet 267mg Hard Capsule is used specifically to treat idiopathic pulmonary fibrosis (IPF), a progressive lung-scarring disease, under the supervision of a respiratory specialist.
Why do I need to avoid the sun while taking this medicine?
Pirfenidone can make your skin much more sensitive to sunlight, increasing the risk of sunburn-like reactions. Sunscreen, protective clothing, and avoiding direct sun exposure and tanning beds are important throughout treatment.
Why is my dose being increased gradually?
Starting at a lower dose and titrating up gradually, as directed by your specialist, helps your body adjust and reduces the chance of nausea and other gastrointestinal side effects during the first few weeks of treatment.
Will I need regular blood tests while taking this medicine?
Yes. Regular liver function blood tests are required throughout treatment, as pirfenidone can, in rare cases, affect the liver.
Can I stop taking this medicine if I feel unwell?
Do not stop or change your dose on your own. Contact your specialist, who will advise whether to continue, adjust, or temporarily pause treatment based on your symptoms.
Can I buy Esbriet 267mg Hard Capsule from DoctorOnCall?
Yes, Esbriet 267mg Hard Capsule is available through DoctorOnCall, a licensed online pharmacy serving our Malaysian and Singaporean customers. As this is a prescription medicine, you will need to complete an online consultation so a doctor can assess your suitability and issue a valid prescription before the order is processed. This ensures the medicine is appropriate for your condition and used under proper medical supervision, whether you are ordering from Malaysia or Singapore.
Is the medication provided by DoctorOnCall genuine and safe to use?
DoctorOnCall sources its medicines through appropriate licensed pharmacy supply channels for our Malaysian and Singaporean customers. All orders are dispensed and checked by a registered pharmacist before delivery. Always use Esbriet 267mg Hard Capsule according to your doctor’s instructions and the information provided with the product.
What payment methods does DoctorOnCall accept?
We accept payment via Online Banking, Credit Card, and e-Wallets (Boost, GrabPay) for our Malaysian and Singaporean customers, so you can choose whichever method is most convenient for you at checkout.
Does DoctorOnCall provide an installment payment plan for Esbriet 267mg Hard Capsule?
DoctorOnCall provides an installment payment plan for eligible Malaysian and Singaporean customers, where applicable. Available plans, eligibility, and terms can vary by market, so please contact DoctorOnCall Customer Service for the latest information on installment options for your order.
Is delivery free, and how much does shipping for Esbriet 267mg Hard Capsule cost?
Delivery charges may vary for our Malaysian and Singaporean customers depending on your delivery location and the applicable order terms at the time of purchase. For the most accurate and up-to-date delivery fee information, please contact DoctorOnCall Customer Service before placing your order.
How long does delivery take for Esbriet 267mg Hard Capsule?
Our Malaysian customers can generally expect delivery within 3-5 working days, while our Singaporean customers generally receive their orders within 5-7 working days. These are expected timeframes rather than guarantees, and actual delivery time may vary depending on your delivery location, order processing time, courier operations, and whether the order falls on a weekend or public holiday.
What is DoctorOnCall’s shipping, return, or cancellation policy for Esbriet 267mg Hard Capsule?
Shipping, return, and cancellation terms may vary for our Malaysian and Singaporean customers depending on the product and your order details. Please refer to DoctorOnCall’s Shipping & Delivery Policy and Return, Refund & Exchange Policy, or contact Customer Service, for the specific terms that apply to your order.
Ingredients / Active Ingredients
- Pirfenidone 267mg
Safety Advice
Pregnancy
This medicine should only be used during pregnancy if prescribed by a doctor after careful evaluation.
Breastfeeding
Generally not recommended while breastfeeding.
Kidney
Use cautiously. Dose adjustment or monitoring may be required.
Liver
Use cautiously. Liver function monitoring may be required.
Alcohol
Caution is advised when consuming alcohol with this medicine.
Driving
Use caution while driving until you know how this medicine affects you.
Medical Review
