Evra 6mg/600mcg Transdermal Patch

Brand Janssen
Manufacturer Janssen
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Dr. Mohd Izzat Amir Bin Awang
Reviewed byDr. Mohd Izzat Amir Bin AwangDoctor of Medicine (MD), University of Mansoura - Manchester
Dr. Adeline Carol Peters
Written byDr. Adeline Carol PetersBachelor of Medicine and Bachelor of Surgery (MBBS) — Manipal Academy of Higher Education (MAHE)

Last updated:

Overview

Evra 6mg/600mcg Transdermal Patch is a patch with Norelgestromin 6mg per patch declared as its active content. It is supplied in pack sizes of 3s and 3s x3.

This is a non-prescription product and can be purchased without a prescription. Only product, safety and handling details are published on this page.

An online consultation with a DoctorOnCall doctor or pharmacist is available for this product, and a registered pharmacist reviews each order before dispatch to Malaysia or Singapore. Follow the directions on the label and on the leaflet inside the pack.

Directions for Use

Apply one patch to clean, dry, intact skin on the buttock, abdomen, upper outer arm, or upper torso, avoiding the breasts and any irritated, cut, or broken skin, pressing firmly for about 10 seconds to ensure good adhesion, and replace with a new patch on the same day each week for 3 weeks, followed by one patch-free week before starting the next cycle, exactly as prescribed by your doctor.

Dosage

One patch is worn continuously for 7 days and replaced on the same ‘patch change day’ for 3 consecutive weeks (21 days total), followed by a 7-day patch-free week during which a withdrawal bleed usually occurs, after which a new 4-week cycle begins; do not extend wear beyond 7 days per patch or leave more than 7 days patch-free without medical advice.

Shelf Life

Evra patches are generally stable for up to 2 to 3 years from the date of manufacture when stored correctly and unopened in their protective sachet; always check the expiry date printed on the sachet and carton before use.

Storage Instructions

Store below 30°C in a cool, dry place away from direct sunlight, keep each patch sealed in its original protective sachet until immediately before application, and keep out of reach and sight of children, noting that used patches still contain active hormone and should be folded sticky-side inward and disposed of carefully.

Side Effects

  • Nausea or vomiting
  • Breast tenderness
  • Headache
  • Bloating
  • Changes in menstrual bleeding
  • Mood changes or mild depression
  • Mild weight changes
  • Skin pigmentation or darkening

Contraindications

  • Women who smoke and are over 35 years of age
  • History of venous or arterial thromboembolism (blood clots), including deep vein thrombosis, pulmonary embolism, stroke, or heart attack
  • Migraine with aura
  • Uncontrolled or severe high blood pressure
  • Certain liver tumours or severe liver disease
  • Known or suspected pregnancy, or undiagnosed abnormal vaginal bleeding
  • Known or suspected hormone-dependent breast or other cancer

Drug / Food Interactions

  • Enzyme-inducing medicines such as certain anticonvulsants (phenytoin, carbamazepine), rifampicin, and some antiretroviral medicines may reduce contraceptive effectiveness
  • St John’s Wort may reduce hormone levels and increase the risk of breakthrough bleeding
  • Certain antibiotics have historically been discussed in relation to reduced contraceptive reliability; inform your doctor of all antibiotics prescribed
  • Applying oils, lotions, creams, or powders to the patch site may reduce adhesion and should be avoided

Quick Tips

  • Apply your new patch on the same day each week to keep the schedule consistent
  • Check the patch daily to make sure it remains firmly attached
  • Rotate the application site each week to reduce skin irritation
  • Do not apply the patch to the breasts or to irritated or broken skin
  • Use a backup contraceptive method if a patch is left off for 24 hours or more
  • Report new leg swelling, chest pain, severe headache, or visual disturbances to your doctor promptly

Ingredients / Active Ingredients

  • Norelgestromin 6mg per patch
  • Ethinylestradiol 600mcg per patch
  • Polyisobutylene/polybutene adhesive matrix
  • Polyester backing film
  • Release liner (removed before application)

Safety Advice

Pregnancy

Not Safe

This medicine is not considered safe during pregnancy and should be avoided.

Breastfeeding

Use With Care

Use with caution. Monitor infant for potential adverse reactions.

Kidney

Use With Care

Use cautiously. Dose adjustment or monitoring may be required.

Liver

Not Advisable

Not recommended in patients with liver disease.

Alcohol

Use With Care

Caution is advised when consuming alcohol with this medicine.

Driving

Generally Safe

This medicine is generally safe and should not impair your driving ability.

Relevant Information

Because Evra is a prescription hormonal contraceptive, your prescribing doctor through DoctorOnCall will review your suitability periodically, including blood pressure checks and a discussion of any new health changes, smoking status, or medicines started since your last consultation, to confirm continued safety of combined hormonal contraception.

Frequently Asked Questions

Product Specifications

BrandJanssen
ManufacturerJanssen
ClassificationNon-prescription
Ingredients / Active IngredientsEthinylestradiol
Pack Size3s, 3s x3

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