HOE Cloderm 0.05% Cream

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Dr. Mohd Izzat Amir Bin Awang
Reviewed byDr. Mohd Izzat Amir Bin AwangDoctor of Medicine (MD), University of Mansoura - Manchester
Dr. Adeline Carol Peters
Written byDr. Adeline Carol PetersBachelor of Medicine and Bachelor of Surgery (MBBS) — Manipal Academy of Higher Education (MAHE)

Last updated:

Overview

HOE Cloderm 0.05% Cream contains Clobetasol Propionate 0.05% and is presented as a cream. It is supplied in a pack size of 15g.

It is classified as a non-prescription medicine, so no prescription is needed to order it. Under Malaysian rules for medicine information, this page carries product, safety and handling information only.

You can consult a doctor or pharmacist online on DoctorOnCall about this product before or after you order. Every order is checked by a registered pharmacist before it is delivered. Always read the label and the leaflet supplied with the pack.

Directions for Use

HOE Cloderm 0.05% Cream should only be used according to the amount, frequency, and duration prescribed by your doctor following an online consultation with DoctorOnCall. A thin layer is applied to clean, affected skin only, gently rubbed in until absorbed, and should not be applied to unaffected surrounding skin. Wash your hands thoroughly after application unless your hands are the area being treated, and do not cover the treated area with a bandage or dressing unless specifically instructed by your doctor.

Dosage

The exact amount and frequency of HOE Cloderm 0.05% Cream is determined individually by your prescribing doctor based on the site, extent, and severity of the skin condition, and is generally limited to once or twice daily for a short, defined course, often not exceeding two to four weeks of continuous use. Do not apply more than the prescribed amount, treat a larger area than advised, or continue beyond the recommended duration without medical review.

Shelf Life

HOE Cloderm 0.05% Cream is generally stable for up to 36 months from the date of manufacture when stored correctly and unopened. Always check the expiry date printed on the tube or carton before use, and do not use the cream if it has expired or if its colour, texture, or smell has changed.

Storage Instructions

Store HOE Cloderm 0.05% Cream at room temperature, below 30 degrees Celsius, away from direct sunlight and excessive heat, and keep the tube tightly closed when not in use. Keep it out of reach of children and pets, and do not use it past its expiry date.

Side Effects

  • Burning, stinging or irritation at the application site
  • Dry or cracked skin
  • Skin thinning (with prolonged use)
  • Changes in skin color
  • Stretch marks
  • Acne or increased hair growth on treated areas

Contraindications

  • Known hypersensitivity to clobetasol propionate or any ingredient in the cream
  • Untreated bacterial, fungal, or viral skin infections, including cold sores, chickenpox, or shingles
  • Rosacea, acne, or perioral dermatitis on the area to be treated
  • Application to the face, groin, or armpits for prolonged periods without doctor advice, due to thinner skin in these areas
  • Not recommended for children without specialist supervision
  • Caution required during pregnancy and breastfeeding; use only if advised by a doctor

Drug / Food Interactions

  • Avoid combining with other topical corticosteroid products on the same area unless directed by your doctor, as this increases total steroid absorption
  • Extensive or prolonged use over large body areas may reduce the effectiveness of live vaccines due to systemic immune effects
  • Inform your doctor of any other topical medicines, moisturisers with active ingredients, or skin treatments you are using
  • No significant food interactions are expected with topical use

Quick Tips

  • Apply HOE Cloderm 0.05% Cream strictly as prescribed and do not exceed the advised duration
  • Use only on the specific areas identified by your doctor, not as a general moisturiser
  • Avoid contact with the eyes, mouth, and mucous membranes
  • Do not use occlusive dressings over the treated area unless instructed
  • Return for review if your skin condition does not improve or worsens
  • Report any signs of infection, unusual skin thinning, or stretch marks promptly

Ingredients / Active Ingredients

  • Clobetasol Propionate 0.05%

Safety Advice

Pregnancy

Use With Care

This medicine should be used cautiously during pregnancy. Monitoring may be required.

Breastfeeding

Use With Care

Use with caution. Monitor infant for potential adverse reactions.

Kidney

Use With Care

Use cautiously. Dose adjustment or monitoring may be required.

Liver

Use With Care

Use cautiously. Liver function monitoring may be required.

Alcohol

Generally Safe

Consuming alcohol with this medicine is generally safe, but moderate intake is advised.

Driving

Generally Safe

This medicine is generally safe and should not impair your driving ability.

Relevant Information

As a super-potent topical corticosteroid, HOE Cloderm 0.05% Cream is generally reserved for severe or resistant skin conditions and prescribed for the shortest effective duration, often followed by a step-down to a milder steroid or a non-steroid maintenance treatment. Extended or excessive use of potent corticosteroids, especially on thin-skinned areas like the face or skin folds, can lead to permanent skin thinning, stretch marks, or rarely, absorption into the bloodstream affecting the body’s natural steroid balance, so regular follow-up with your doctor is important.

Frequently Asked Questions

Product Specifications

BrandHoe Pharmaceuticals
ClassificationNon-prescription
Ingredients / Active IngredientsClobetasol
Weight15g

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Important Medical Information

💊 Recommended Dosage:

The exact amount and frequency of HOE Cloderm 0.05% Cream is determined individually by your prescribing doctor based on the site, extent, and severity of the skin condition, and is generally limited to once or twice daily for a short, defined course, often not exceeding two to four weeks of continuous use. Do not apply more than the prescribed amount, treat a larger area than advised, or continue beyond the recommended duration without medical review.

🛑 Contraindications (Do not use if):
  • Known hypersensitivity to clobetasol propionate or any ingredient in the cream
  • Untreated bacterial, fungal, or viral skin infections, including cold sores, chickenpox, or shingles
  • Rosacea, acne, or perioral dermatitis on the area to be treated
  • Application to the face, groin, or armpits for prolonged periods without doctor advice, due to thinner skin in these areas
  • Not recommended for children without specialist supervision
  • Caution required during pregnancy and breastfeeding; use only if advised by a doctor
If you are unsure, please chat with us or consult your doctor.
⚠️ Common Side Effects:
  • Burning, stinging or irritation at the application site
  • Dry or cracked skin
  • Skin thinning (with prolonged use)
  • Changes in skin color
  • Stretch marks
  • Acne or increased hair growth on treated areas
Stop taking this medication immediately and consult your doctor if you experience severe allergic reactions or side effects.
IMPORTANT: Unsure? Chat with our pharmacists (Mon - Sat, 9:00am - 6:00pm) before buying.