HOE Locoa 40mg Transdermal Patch

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Dr. Mohd Izzat Amir Bin Awang
Reviewed byDr. Mohd Izzat Amir Bin AwangDoctor of Medicine (MD), University of Mansoura - Manchester
Dr. Chong Zhan Pong
Written byDr. Chong Zhan PongDoctor of Medicine (MD), International Medical University (IMU)

Overview

HOE Locoa 40mg Transdermal Patch is a patch with Esflurbiprofen 40mg (active NSAID ingredient per patch) declared as its active content. It is supplied in a pack size of 7 patches.

This is a non-prescription product and can be purchased without a prescription. Only product, safety and handling details are published on this page.

An online consultation with a DoctorOnCall doctor or pharmacist is available for this product, and a registered pharmacist reviews each order before dispatch to Malaysia or Singapore. Follow the directions on the label and on the leaflet inside the pack.

Directions for Use

Clean and dry the affected area of skin before use, then remove the protective backing and apply one patch to the painful joint or muscle area as directed by your doctor, pressing it down firmly so the edges adhere well; do not apply to broken, irritated, or infected skin, and change the patch at the interval your doctor recommends (commonly once daily).

Dosage

Your doctor will confirm the exact regimen, but HOE Locoa 40mg Transdermal Patch is generally applied as one patch to the affected area once daily; do not apply more than one patch to the same area at a time, and do not use for longer than the duration prescribed without a follow-up review.

Storage Instructions

Store below 30°C in a dry place away from direct sunlight and heat, keep each patch in its sealed sachet until ready to use, and keep out of the reach and sight of children and pets — used patches still contain active drug and should be folded sticky-side inward and disposed of safely.

Side Effects

  • Local skin redness, itching, or irritation at the application site
  • Mild burning or rash where the patch was applied
  • Headache
  • Stomach discomfort or nausea (less common than with oral NSAIDs, but still possible)
  • Dizziness
  • Rarely, an allergic skin reaction requiring the patch to be removed and medical advice sought

Contraindications

  • Known hypersensitivity to esflurbiprofen, flurbiprofen, aspirin, or other NSAIDs
  • History of asthma, urticaria, or allergic reactions triggered by NSAIDs or aspirin
  • Active or history of peptic ulcer or gastrointestinal bleeding
  • Severe heart, liver, or kidney impairment
  • Third trimester of pregnancy
  • Application on broken, infected, or eczematous skin

Drug / Food Interactions

  • Other oral or topical NSAIDs, or aspirin, may increase the total NSAID load and risk of side effects
  • Blood-thinning medicines (e.g., warfarin) may have an increased bleeding risk when combined with NSAIDs
  • ACE inhibitors, ARBs, or diuretics used for blood pressure may interact with NSAIDs, affecting kidney function or blood pressure control
  • Corticosteroids used together with NSAIDs can increase the risk of gastrointestinal side effects
  • Always tell your doctor about all other medicines you are taking, including supplements

Quick Tips

  • Apply to clean, dry, intact skin over the painful area for the best adhesion and absorption
  • Do not apply heat pads or hot compresses over the patch, as this can increase drug absorption
  • Rotate the application site slightly with each new patch to reduce skin irritation
  • Fold used patches sticky-side inward before disposal, as they still contain active medicine
  • Contact your doctor if pain does not improve, or if you notice stomach pain, black stools, or unusual bruising

Ingredients / Active Ingredients

  • Esflurbiprofen 40mg (active NSAID ingredient per patch)
  • Adhesive patch matrix base to hold the drug against the skin
  • Backing film/liner layers typical of transdermal patch systems
  • Permeation-enhancing excipients to support absorption through the skin

Relevant Information

The confirmed active ingredient in HOE Locoa 40mg Transdermal Patch is esflurbiprofen, an NSAID delivered through the skin — this product should not be confused with loxapine, an unrelated antipsychotic medicine with no patch formulation. As a prescription NSAID patch, ongoing use should be reviewed periodically by your doctor, especially in older adults or those with existing stomach, kidney, or heart conditions, since topical NSAIDs can still be absorbed into the bloodstream to a degree.

Frequently Asked Questions

Product Specifications

BrandHoe Pharmaceuticals
ClassificationNon-prescription
Form7 patches
Shelf LifeUnopened and stored correctly, the patches are generally stable for up to around 2 to 3 years from manufacture; always check the expiry date printed on the sachet or carton and do not use beyond this date.

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