Isentress 400mg Tablet

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Prescription Required

Orders placed now will be queued. A doctor will contact you on the next working day for approval.

Overview

Isentress 400mg Tablet is a prescription-only medicine (POM) that contains Raltegravir 400mg (as raltegravir potassium). It is supplied as a tablet and is dispensed in Malaysia only against a valid prescription issued by a registered doctor.

Under Malaysian rules for prescription medicines, this page carries product, safety and handling information only. Your doctor or pharmacist will explain whether this medicine is suitable for you, the dose you should take, and how long you should take it.

On DoctorOnCall, Isentress 400mg Tablet is reviewed by a licensed doctor through an online consultation and dispensed by a registered pharmacist before delivery. Always follow the instructions on your prescription label and the package insert supplied with the product, and do not share this medicine with anyone else.

Directions for Use

Take Isentress 400mg Tablet exactly as prescribed by your HIV specialist, at the same times each day, with or without food, as part of your full antiretroviral regimen. Do not skip, delay, or stop any of your medicines without first speaking to your specialist, as gaps in treatment can reduce its effectiveness and encourage drug-resistant virus to develop.

Dosage

Isentress 400mg Tablet is taken as part of a combination antiretroviral regimen individualised by your HIV specialist, who will determine the exact dose, frequency, and the other medicines to be combined with it based on your treatment history and viral resistance testing. Strict, consistent daily adherence is essential – never change your dose or regimen without your specialist’s guidance, as inconsistent use can allow the virus to develop resistance.

Shelf Life

Use this product before the expiry date stated on the packaging. Do not use the medicine if the expiry date has passed.

Storage Instructions

Store below 30°C in a dry place, away from direct sunlight and out of reach of children.

Side Effects

  • Headache
  • Trouble sleeping (insomnia)
  • Nausea
  • Tiredness or fatigue
  • Dizziness
  • Diarrhea
  • Abdominal pain
  • Rash (rarely serious but requires attention)

Contraindications

  • Known hypersensitivity to raltegravir or any ingredient in this product
  • Use only as part of a supervised combination antiretroviral regimen – never as a single agent or without specialist guidance

Drug / Food Interactions

  • Rifampicin significantly lowers raltegravir blood levels and requires a dose adjustment supervised by your specialist
  • Other strong inducers of drug-metabolising enzymes (e.g. certain anticonvulsants, St John’s Wort) may also reduce raltegravir levels
  • Aluminium- or magnesium-containing antacids can reduce raltegravir absorption – your specialist may advise spacing doses apart
  • Always tell your HIV specialist about every other prescription, over-the-counter, or herbal product you take, as interactions with antiretroviral regimens can be complex

Quick Tips

  • Take every dose of your full regimen at the same times daily – consistent adherence is essential to keep the virus suppressed
  • Never stop, skip, or change your antiretroviral regimen without speaking to your HIV specialist first
  • Attend all scheduled clinic visits and blood tests to monitor your viral load, immune status, and treatment response
  • Tell your specialist about any new medicines, including over-the-counter or herbal products, before starting them
  • Contact your doctor immediately if you experience unexplained muscle symptoms, a severe rash, or fever
  • Continue safer-sex and other prevention practices as advised by your specialist, as treatment lowers but does not eliminate transmission risk

Frequently Asked Questions

Is Isentress 400mg Tablet a prescription medicine?

Yes. Isentress 400mg Tablet is a prescription-only medicine (POM). It can only be supplied against a valid prescription written by a registered doctor, and it should be used only by the person named on the prescription label.

What does Isentress 400mg Tablet contain?

Isentress 400mg Tablet is supplied as a tablet and contains Raltegravir 400mg (as raltegravir potassium). The full composition is listed in the Composition section on this page and on the product packaging.

Why is there no information here about what Isentress 400mg Tablet is for?

Malaysian rules for prescription medicines limit public product pages to product, safety and handling information. Your doctor decides whether this medicine is appropriate for you and will explain it during your consultation, and your pharmacist can answer further questions when the medicine is dispensed.

How should I take Isentress 400mg Tablet?

Follow your doctor’s instructions and the directions on the dispensing label without changing them. If anything on the label is unclear, check with your pharmacist before taking the first dose, and read the Directions for Use section on this page.

What should I do if I miss a dose?

Take it as soon as you remember, unless your next dose is nearly due. In that case skip the missed dose and carry on with your usual schedule. Never take two doses together to make up for a missed one. If you miss doses often, tell your doctor or pharmacist.

How should I store Isentress 400mg Tablet?

Store below 30°C in a dry place, away from direct sunlight and out of reach of children. Keep it in the original pack until use, and do not use it after the expiry date printed on the packaging.

What should I do if I notice side effects?

Tell your doctor or pharmacist about any reaction that concerns you, and seek medical care immediately for signs of a severe reaction such as difficulty breathing, swelling of the face, lips or throat, or a widespread rash. Reported reactions are listed in the Side Effects section on this page.

Can I stop taking Isentress 400mg Tablet on my own?

No. Speak to your doctor before stopping, pausing or changing the dose, even if you feel well or think you no longer need the medicine.

How do I get a prescription for Isentress 400mg Tablet?

Customers in Malaysia can complete an online consultation with a DoctorOnCall doctor, who decides whether a prescription is appropriate, or upload a valid prescription already issued by their own doctor.

Orders going to Singapore are dispatched from Malaysia as an international delivery, so you need to hold a valid prescription or doctor’s letter for the medicine. Check the consultation and prescription upload options shown at checkout for your delivery address before placing the order.

How long will delivery take?

Within Malaysia, standard delivery takes 3 to 5 working days. Same-day delivery is available in the Klang Valley for orders placed before 12pm; orders placed after 12pm arrive by the end of the next day.

Orders to Singapore are sent as international deliveries and take 5 to 9 working days. A lump-sum shipping and handling fee applies to every overseas delivery and is shown at checkout.

What payment methods can I use?

Customers in Malaysia can pay by FPX online banking, credit or debit card (Visa and Mastercard), and supported e-wallets including Touch ‘n Go eWallet, GrabPay and ShopeePay.

FPX and local e-wallets are tied to Malaysian bank and wallet accounts, so if your delivery address is in Singapore, use the payment options displayed at checkout for that address rather than assuming the same list applies.

Can Isentress 400mg Tablet be delivered to Singapore?

Yes. DoctorOnCall ships to Singapore as an international order dispatched from Malaysia, arriving in 5 to 9 working days with a lump-sum shipping and handling fee.

Singapore’s Health Sciences Authority (HSA) allows personal imports of up to three months’ supply of a medicine for your own use or an immediate family member’s, as long as it contains no controlled drugs, psychotropic substances or prohibited items. Keep the product in its original labelled packaging and keep a copy of your prescription or doctor’s letter with it. Quantities above three months’ supply, and medicines containing controlled substances, require prior HSA approval.

Is Isentress 400mg Tablet registered with the authorities?

Products listed on DoctorOnCall are registered with Malaysia’s Ministry of Health for supply in Malaysia, and each pack carries its MAL registration number.

An order delivered to Singapore arrives as a personal import of a Malaysia-registered product; HSA product registration is not required for personal-use quantities, but it is also not the same as a product registered for sale in Singapore. If you need a locally registered Singapore product, buy it from a pharmacy in Singapore.

Who do I contact if there is a problem with my order?

DoctorOnCall’s customer care team handles order, delivery and product queries through the contact channels on the site, including WhatsApp and the online help centre.

For deliveries to Singapore, allow more time before chasing an order than you would for a local Malaysian delivery, as the parcel passes through customs clearance and tracking updates can appear later in the journey.

Ingredients / Active Ingredients

  • Raltegravir 400mg (as raltegravir potassium)

Safety Advice

Pregnancy

Limited Data

Limited information is available regarding use during pregnancy. Use only if clearly needed.

Breastfeeding

Not Advisable

Generally not recommended while breastfeeding.

Kidney

Use With Care

Use cautiously. Dose adjustment or monitoring may be required.

Liver

Use With Care

Use cautiously. Liver function monitoring may be required.

Alcohol

Use With Care

Caution is advised when consuming alcohol with this medicine.

Driving

Not Advisable

It is not advisable to drive if you experience side effects from this medicine.

Medical Review

Written by:

Dr. Chong Zhan Pong

Doctor of Medicine (MD), International Medical University (IMU)

Reviewed by:

Dr. Mohd Izzat Amir Bin Awang

Doctor of Medicine (MD), University of Mansoura - Manchester

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