Kaletra 200/50mg Tablet

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Brand AbbVie
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Prescription Required

Orders placed now will be queued. A doctor will contact you on the next working day for approval.

Overview

Kaletra 200/50mg Tablet is a prescription-only medicine (POM) presented as a tablet, with Lopinavir 200mg and Ritonavir 50mg as its active ingredient content.

This page is limited to product, safety and handling information, in line with Malaysian rules on prescription medicine information for the public. Your prescriber or pharmacist is the right source for anything beyond that, together with the leaflet inside the pack.

Through DoctorOnCall, this product is supplied after an online consultation with a licensed doctor and a valid prescription, and it is checked by a registered pharmacist before dispensing. Take it exactly as prescribed, and speak to your doctor before stopping, changing the dose, or starting any other medicine alongside it.

Directions for Use

Take Kaletra 200/50mg Tablet with or without food, at evenly spaced times about 12 hours apart, exactly as prescribed by your HIV specialist. Swallow the tablets whole – do not crush or chew them. Strict, consistent daily adherence is essential, as missed or irregular doses increase the risk of the virus becoming resistant to treatment.

Dosage

The usual adult dose of Kaletra 200/50mg Tablet is two tablets twice daily, taken as part of a combination antiretroviral regimen prescribed by your HIV specialist. Your doctor will determine your full regimen and monitor your response – never adjust the dose or regimen on your own.

Shelf Life

Use this product before the expiry date stated on the packaging. Do not use the medicine if the expiry date has passed.

Storage Instructions

Store below 30°C in a dry place, away from direct sunlight and out of reach of children.

Side Effects

  • Nausea or vomiting
  • Diarrhoea
  • Abdominal pain
  • Headache
  • Dizziness
  • Fatigue
  • Changes in taste
  • Increased cholesterol or triglyceride levels
  • Mouth or throat pain

Contraindications

  • Known hypersensitivity to lopinavir, ritonavir, or any ingredient in this product
  • Severe liver impairment
  • Concomitant use with medicines highly dependent on CYP3A4 for clearance where increased plasma concentrations are associated with serious or life-threatening reactions (e.g. certain ergot derivatives, certain sedatives, some antiarrhythmics) – your doctor and pharmacist will check your full medicine list before starting

Drug / Food Interactions

  • Ritonavir is a strong inhibitor of the CYP3A4 liver enzyme, so it can significantly increase blood levels of many other medicines processed by this pathway – this is one of the most extensive interaction profiles among HIV medicines and must be checked carefully with every new prescription
  • Certain statins (e.g. simvastatin, lovastatin) can reach dangerously high levels and are generally avoided in combination
  • Hormonal contraceptives may become less effective, so alternative or additional contraception may be needed
  • St John’s Wort and certain anti-seizure medicines can reduce lopinavir/ritonavir levels and should be avoided unless specifically approved by your doctor

Quick Tips

  • Take this medicine every day, at the same times, without missing doses, to keep the virus suppressed and reduce resistance risk
  • Always tell every doctor, dentist, or pharmacist that you are taking this medicine before they prescribe anything new, given its extensive interaction potential
  • Never start, stop, or change any other medicine, including over-the-counter products and herbal supplements, without checking with your HIV specialist first
  • Report persistent vomiting, severe abdominal pain, or yellowing of the skin/eyes promptly
  • Keep all scheduled HIV specialist appointments and blood tests to monitor your viral load and treatment response

Frequently Asked Questions

Is Kaletra 200/50mg Tablet a prescription medicine?

Yes. Kaletra 200/50mg Tablet is a prescription-only medicine (POM). It can only be supplied against a valid prescription written by a registered doctor, and it should be used only by the person named on the prescription label.

What does Kaletra 200/50mg Tablet contain?

Kaletra 200/50mg Tablet is supplied as a tablet and contains Lopinavir 200mg and Ritonavir 50mg. The full composition is listed in the Composition section on this page and on the product packaging.

Why is there no information here about what Kaletra 200/50mg Tablet is for?

Malaysian rules for prescription medicines limit public product pages to product, safety and handling information. Your doctor decides whether this medicine is appropriate for you and will explain it during your consultation, and your pharmacist can answer further questions when the medicine is dispensed.

How should I take Kaletra 200/50mg Tablet?

Take it exactly as written on your prescription label. Do not increase, reduce or skip doses on your own, and do not continue beyond the period your doctor has prescribed. Practical handling steps are set out in the Directions for Use section on this page.

What should I do if I miss a dose?

Take it as soon as you remember, unless your next dose is nearly due. In that case skip the missed dose and carry on with your usual schedule. Never take two doses together to make up for a missed one. If you miss doses often, tell your doctor or pharmacist.

How should I store Kaletra 200/50mg Tablet?

Store below 30°C in a dry place, away from direct sunlight and out of reach of children. Keep it in the original pack until use, and do not use it after the expiry date printed on the packaging.

What should I do if I notice side effects?

Tell your doctor or pharmacist about any reaction that concerns you, and seek medical care immediately for signs of a severe reaction such as difficulty breathing, swelling of the face, lips or throat, or a widespread rash. Reported reactions are listed in the Side Effects section on this page.

Can I stop taking Kaletra 200/50mg Tablet on my own?

No. Speak to your doctor before stopping, pausing or changing the dose, even if you feel well or think you no longer need the medicine.

How do I get a prescription for Kaletra 200/50mg Tablet?

Customers in Malaysia can complete an online consultation with a DoctorOnCall doctor, who decides whether a prescription is appropriate, or upload a valid prescription already issued by their own doctor.

Orders going to Singapore are dispatched from Malaysia as an international delivery, so you need to hold a valid prescription or doctor’s letter for the medicine. Check the consultation and prescription upload options shown at checkout for your delivery address before placing the order.

How long will delivery take?

Within Malaysia, standard delivery takes 3 to 5 working days. Same-day delivery is available in the Klang Valley for orders placed before 12pm; orders placed after 12pm arrive by the end of the next day.

Orders to Singapore are sent as international deliveries and take 5 to 9 working days. A lump-sum shipping and handling fee applies to every overseas delivery and is shown at checkout.

What payment methods can I use?

Customers in Malaysia can pay by FPX online banking, credit or debit card (Visa and Mastercard), and supported e-wallets including Touch ‘n Go eWallet, GrabPay and ShopeePay.

FPX and local e-wallets are tied to Malaysian bank and wallet accounts, so if your delivery address is in Singapore, use the payment options displayed at checkout for that address rather than assuming the same list applies.

Can Kaletra 200/50mg Tablet be delivered to Singapore?

Yes. DoctorOnCall ships to Singapore as an international order dispatched from Malaysia, arriving in 5 to 9 working days with a lump-sum shipping and handling fee.

Singapore’s Health Sciences Authority (HSA) allows personal imports of up to three months’ supply of a medicine for your own use or an immediate family member’s, as long as it contains no controlled drugs, psychotropic substances or prohibited items. Keep the product in its original labelled packaging and keep a copy of your prescription or doctor’s letter with it. Quantities above three months’ supply, and medicines containing controlled substances, require prior HSA approval.

Is Kaletra 200/50mg Tablet registered with the authorities?

Products listed on DoctorOnCall are registered with Malaysia’s Ministry of Health for supply in Malaysia, and each pack carries its MAL registration number.

An order delivered to Singapore arrives as a personal import of a Malaysia-registered product; HSA product registration is not required for personal-use quantities, but it is also not the same as a product registered for sale in Singapore. If you need a locally registered Singapore product, buy it from a pharmacy in Singapore.

Who do I contact if there is a problem with my order?

DoctorOnCall’s customer care team handles order, delivery and product queries through the contact channels on the site, including WhatsApp and the online help centre.

For deliveries to Singapore, allow more time before chasing an order than you would for a local Malaysian delivery, as the parcel passes through customs clearance and tracking updates can appear later in the journey.

Ingredients / Active Ingredients

  • Lopinavir 200mg
  • Ritonavir 50mg

Safety Advice

Pregnancy

Use With Care

This medicine should be used cautiously during pregnancy. Monitoring may be required.

Breastfeeding

Not Advisable

Generally not recommended while breastfeeding.

Kidney

Limited Data

Limited data in kidney disease patients. Use only if necessary.

Liver

Limited Data

Limited data available in liver disease patients.

Alcohol

Limited Data

Limited data is available regarding the effects of alcohol with this medicine.

Driving

Use With Care

Use caution while driving until you know how this medicine affects you.

Medical Review

Written by:

Dr. Chong Zhan Pong

Doctor of Medicine (MD), International Medical University (IMU)

Reviewed by:

Dr. Mohd Izzat Amir Bin Awang

Doctor of Medicine (MD), University of Mansoura - Manchester

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