Kytril 1mg Tablet

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Prescription Required

Orders placed now will be queued. A doctor will contact you on the next working day for approval.

Overview

Kytril 1mg Tablet contains granisetron 1mg, a 5-HT3 receptor antagonist antiemetic used mainly to prevent nausea and vomiting associated with cancer chemotherapy or radiotherapy, and sometimes to prevent nausea and vomiting after surgery.

Granisetron works by blocking serotonin (5-HT3) receptors both in the gut and in the chemoreceptor trigger zone of the brain. Chemotherapy and radiotherapy cause serotonin to be released from cells in the gut wall, which activates these receptors and triggers nausea and vomiting; by blocking them, granisetron prevents this signal from reaching the brain’s vomiting centre.

How it Works

Granisetron selectively blocks 5-HT3 (serotonin) receptors on vagal nerve endings in the gastrointestinal tract and in the brainstem’s chemoreceptor trigger zone. Chemotherapy and radiotherapy damage cells lining the gut, causing them to release serotonin, which would normally trigger the vomiting reflex. By blocking the 5-HT3 receptors these signals act on, granisetron interrupts this pathway and prevents nausea and vomiting from developing.

Directions for Use

Take Kytril 1mg Tablet exactly as instructed by your oncology or surgical care team, usually before your chemotherapy, radiotherapy, or surgery is due to start. It can be taken with or without food. If you are given this medicine to continue at home, follow the specific timing instructions provided, and do not adjust the schedule without checking with your care team.

Dosage

Kytril 1mg Tablet is dosed according to your oncology or surgical care team’s specific protocol, usually timed shortly before chemotherapy, radiotherapy, or surgery begins, with further doses given as directed. Your doctor will determine the exact dose and schedule based on the treatment you are receiving and how you respond.

Shelf Life

Use this product before the expiry date stated on the packaging. Do not use the medicine if the expiry date has passed.

Storage Instructions

Store below 30°C in a dry place, away from direct sunlight and out of reach of children.

Side Effects

  • Headache
  • Constipation
  • Fatigue or tiredness
  • Dizziness
  • Trouble sleeping
  • Mild abdominal discomfort

Contraindications

  • Known hypersensitivity to granisetron or other 5-HT3 receptor antagonists
  • Caution in patients with existing heart rhythm problems or those taking other medicines that can prolong the QT interval

Drug / Food Interactions

  • Other medicines that can prolong the QT interval (certain antiarrhythmics, some antibiotics, some antipsychotics) may increase the risk of heart rhythm disturbances when combined with granisetron
  • Apomorphine should not be combined with 5-HT3 receptor antagonists such as granisetron, as this combination has been associated with profound low blood pressure and loss of consciousness
  • Always inform your care team of all medicines you are taking, including those for unrelated conditions, before starting granisetron

Quick Tips

  • Take this medicine exactly at the times instructed around your chemotherapy, radiotherapy, or surgery schedule
  • Increase fluid and fibre intake if you notice constipation, and tell your care team if it persists
  • Report any palpitations or an irregular heartbeat to your care team promptly
  • Tell your doctor about all other medicines you take, especially any that affect heart rhythm
  • Continue any other prescribed anti-nausea measures alongside this medicine, as directed by your oncology team

Frequently Asked Questions

What is Kytril 1mg Tablet used for?

Kytril 1mg Tablet is used to prevent nausea and vomiting caused by cancer chemotherapy, radiotherapy, or surgery.

When should this medicine be taken in relation to my chemotherapy or surgery?

It is usually given shortly before chemotherapy, radiotherapy, or surgery begins, following the specific schedule set by your oncology or surgical care team, to prevent nausea before it starts rather than treating it after it has begun.

Will this medicine make me drowsy?

Granisetron generally causes less sedation than some older antiemetic medicines, though fatigue can still occur. Be cautious with driving or operating machinery until you know how it affects you.

Can this medicine be used for morning sickness or motion sickness?

No, granisetron is specifically used for chemotherapy-, radiotherapy-, or surgery-related nausea and vomiting under medical supervision, and is not intended for general nausea, motion sickness, or morning sickness in pregnancy.

Is it safe to take this medicine together with other anti-sickness medicines?

Your oncology team may prescribe granisetron alongside other antiemetics (such as corticosteroids) as part of a combined prevention strategy – always follow their specific instructions rather than combining medicines on your own.

What should I do if my nausea is not controlled by this medicine?

Tell your oncology or care team promptly, as they may adjust your antiemetic regimen or add another medicine to better control your symptoms.

Can I buy Kytril 1mg Tablet from DoctorOnCall?

Yes, Kytril 1mg Tablet is available through DoctorOnCall, a licensed online pharmacy serving our Malaysian and Singaporean customers. As this is a prescription medicine, you will need to complete an online consultation so a doctor can assess your suitability and issue a valid prescription before the order is processed. This ensures the medicine is appropriate for your condition and used under proper medical supervision, whether you are ordering from Malaysia or Singapore.

Is the medication provided by DoctorOnCall genuine and safe to use?

DoctorOnCall sources its medicines through appropriate licensed pharmacy supply channels for our Malaysian and Singaporean customers. All orders are dispensed and checked by a registered pharmacist before delivery. Always use Kytril 1mg Tablet according to your doctor’s instructions and the information provided with the product.

What payment methods does DoctorOnCall accept?

We accept payment via Online Banking, Credit Card, and e-Wallets (Boost, GrabPay) for our Malaysian and Singaporean customers, so you can choose whichever method is most convenient for you at checkout.

Does DoctorOnCall provide an installment payment plan for Kytril 1mg Tablet?

DoctorOnCall provides an installment payment plan for eligible Malaysian and Singaporean customers, where applicable. Available plans, eligibility, and terms can vary by market, so please contact DoctorOnCall Customer Service for the latest information on installment options for your order.

Is delivery free, and how much does shipping for Kytril 1mg Tablet cost?

Delivery charges may vary for our Malaysian and Singaporean customers depending on your delivery location and the applicable order terms at the time of purchase. For the most accurate and up-to-date delivery fee information, please contact DoctorOnCall Customer Service before placing your order.

How long does delivery take for Kytril 1mg Tablet?

Our Malaysian customers can generally expect delivery within 3-5 working days, while our Singaporean customers generally receive their orders within 5-7 working days. These are expected timeframes rather than guarantees, and actual delivery time may vary depending on your delivery location, order processing time, courier operations, and whether the order falls on a weekend or public holiday.

What is DoctorOnCall’s shipping, return, or cancellation policy for Kytril 1mg Tablet?

Shipping, return, and cancellation terms may vary for our Malaysian and Singaporean customers depending on the product and your order details. Please refer to DoctorOnCall’s Shipping & Delivery Policy and Return, Refund & Exchange Policy, or contact Customer Service, for the specific terms that apply to your order.

Ingredients / Active Ingredients

  • Granisetron 1mg (as granisetron hydrochloride)

Safety Advice

Pregnancy

Safe If Prescribed

This medicine should only be used during pregnancy if prescribed by a doctor after careful evaluation.

Breastfeeding

Use With Care

Use with caution. Monitor infant for potential adverse reactions.

Kidney

Use With Care

Use cautiously. Dose adjustment or monitoring may be required.

Liver

Generally Safe

Generally safe, but caution may be required in some patients.

Alcohol

Use With Care

Caution is advised when consuming alcohol with this medicine.

Driving

Safe

This medicine does not affect your ability to drive.

Medical Review

Written by:

Dr. Chong Zhan Pong

Doctor of Medicine (MD), International Medical University (IMU)

Reviewed by:

Dr. Mohd Izzat Amir Bin Awang

Doctor of Medicine (MD), University of Mansoura - Manchester

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