Lixiana Edoxaban Film-Coated 30mg Tablet

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Dr. Mohd Izzat Amir Bin Awang
Reviewed byDr. Mohd Izzat Amir Bin AwangDoctor of Medicine (MD), University of Mansoura - Manchester
Dr. Chong Zhan Pong
Written byDr. Chong Zhan PongDoctor of Medicine (MD), International Medical University (IMU)

Last updated:

Overview

Lixiana Edoxaban Film-Coated 30mg Tablet is a prescription-only medicine (POM) presented as a tablet, with Edoxaban 30mg (as edoxaban tosilate) as its active ingredient content.

This page is limited to product, safety and handling information, in line with Malaysian rules on prescription medicine information for the public. Your prescriber or pharmacist is the right source for anything beyond that, together with the leaflet inside the pack.

Through DoctorOnCall, this product is supplied after an online consultation with a licensed doctor and a valid prescription, and it is checked by a registered pharmacist before dispensing. Take it exactly as prescribed, and speak to your doctor before stopping, changing the dose, or starting any other medicine alongside it.

Directions for Use

Take Lixiana Edoxaban Film-Coated 30mg Tablet once daily, at about the same time each day, with or without food. Swallow the tablet whole with water; do not crush or split it unless your doctor or pharmacist has advised you it is safe to do so. Because this is a blood-thinning medicine, always carry information about your treatment with you and inform any doctor, dentist, or surgeon that you are taking Lixiana Edoxaban Film-Coated 30mg Tablet before any procedure.

Dosage

Lixiana Edoxaban Film-Coated 30mg Tablet is usually taken once daily, and your doctor will select the appropriate dose based on your body weight, kidney function, and any interacting medicines you are taking – the 30mg dose is typically used as a dose-reduced regimen for patients meeting specific criteria. Never adjust the dose yourself; always take this medicine exactly as prescribed and attend all scheduled follow-up appointments.

Storage Instructions

Store below 30°C in a dry place, away from direct sunlight and out of reach of children.

Side Effects

  • Bleeding, such as easy bruising, nosebleeds, or bleeding gums
  • Abnormal liver function test results
  • Rash or skin reactions
  • Dizziness
  • Serious: signs of significant bleeding (blood in urine or stools, black tarry stools, coughing up blood, unusual bruising, prolonged bleeding from cuts) or symptoms of stroke (sudden weakness, slurred speech, severe headache) require immediate medical attention

Contraindications

  • Known hypersensitivity to edoxaban or any ingredient in this product
  • Active clinically significant bleeding
  • Conditions with a significant risk of major bleeding, such as active peptic ulcer disease
  • Severe liver impairment associated with coagulopathy
  • Pregnancy and breastfeeding

Drug / Food Interactions

  • Other anticoagulants, antiplatelet drugs (e.g. aspirin, clopidogrel), or NSAIDs significantly increase bleeding risk
  • Rifampicin, phenytoin, carbamazepine, and St John’s Wort may reduce edoxaban’s effectiveness
  • Ketoconazole, ciclosporin, dronedarone, and erythromycin may increase edoxaban blood levels and bleeding risk
  • Inform your doctor before taking any herbal supplements or over-the-counter medicines, as many can affect bleeding risk

Quick Tips

  • Never stop or adjust this medicine without first speaking to your doctor, even briefly
  • Always inform every doctor, dentist, and pharmacist that you are taking this medicine before any procedure or new prescription
  • Watch for and promptly report unusual bruising or bleeding
  • Use a soft-bristled toothbrush and an electric razor to reduce the chance of minor bleeding
  • Carry an anticoagulant alert card or wear a medical alert bracelet
  • Do not take double doses to make up for a missed dose

Ingredients / Active Ingredients

  • Edoxaban 30mg (as edoxaban tosilate)

Frequently Asked Questions

Product Specifications

BrandA. Menarini
ClassificationPrescription medicine
Pack Size28s
Shelf LifeUse this product before the expiry date stated on the packaging. Do not use the medicine if the expiry date has passed.

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