Lixiana Edoxaban Film-Coated 60mg Tablet

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Dr. Mohd Izzat Amir Bin Awang
Reviewed byDr. Mohd Izzat Amir Bin AwangDoctor of Medicine (MD), University of Mansoura - Manchester
Dr. Chong Zhan Pong
Written byDr. Chong Zhan PongDoctor of Medicine (MD), International Medical University (IMU)

Last updated:

Overview

Lixiana Edoxaban Film-Coated 60mg Tablet is a prescription-only medicine (POM) presented as a tablet, with Edoxaban 60mg (as edoxaban tosilate) as its active ingredient content.

This page is limited to product, safety and handling information, in line with Malaysian rules on prescription medicine information for the public. Your prescriber or pharmacist is the right source for anything beyond that, together with the leaflet inside the pack.

Through DoctorOnCall, this product is supplied after an online consultation with a licensed doctor and a valid prescription, and it is checked by a registered pharmacist before dispensing. Take it exactly as prescribed, and speak to your doctor before stopping, changing the dose, or starting any other medicine alongside it.

Directions for Use

Take Lixiana Edoxaban Film-Coated 60mg Tablet once daily at the same time each day, with or without food. Swallow the tablet whole with water. If a dose is missed, do not take an extra dose to make up for it – contact your doctor or pharmacist for specific guidance on what to do, as this can vary depending on your individual situation.

Dosage

The usual dose of Lixiana Edoxaban Film-Coated 60mg Tablet is one tablet once daily, but your doctor may prescribe a lower dose based on your kidney function, body weight, or use of certain other medicines. Never adjust your dose or stop this medicine on your own – always follow your doctor’s exact instructions, as both under- and over-anticoagulation carry serious risks.

Storage Instructions

Store below 30°C in a dry place, away from direct sunlight and out of reach of children.

Side Effects

  • Easy bruising
  • Nosebleeds or minor bleeding from gums when brushing teeth
  • Anaemia (low red blood cell count)
  • Rash or skin reactions
  • Serious: unusual or heavy bleeding (blood in urine or stool, black/tarry stools, coughing or vomiting blood, unusually heavy menstrual bleeding), severe headache, or signs of internal bleeding (unexplained swelling, severe weakness) require IMMEDIATE medical attention

Contraindications

  • Known hypersensitivity to edoxaban or any ingredient in this product
  • Active, clinically significant bleeding
  • Conditions with a significant risk of major bleeding, such as active peptic ulcer disease or recent brain/spinal injury or surgery
  • Severe uncontrolled hypertension
  • Concurrent use with other anticoagulants, except in specific defined circumstances directed by your doctor (e.g. switching between anticoagulants)
  • Pregnancy and breastfeeding

Drug / Food Interactions

  • Other anticoagulants (e.g. warfarin, heparin) or antiplatelet medicines (e.g. aspirin, clopidogrel) significantly increase the risk of bleeding when combined
  • NSAIDs (e.g. ibuprofen, diclofenac) increase the risk of gastrointestinal bleeding when combined with edoxaban
  • Strong P-glycoprotein inhibitors (e.g. certain antifungal or antibiotic medicines) can increase edoxaban blood levels and bleeding risk
  • Always inform every healthcare provider – including your dentist and any surgeon – that you are taking this medicine before any procedure

Quick Tips

  • Never stop or adjust this medicine without your doctor’s advice, even briefly, as stopping suddenly increases the risk of stroke or clotting
  • Tell every doctor, dentist, and other healthcare provider that you are taking this medicine before any procedure, including dental work
  • Seek immediate medical attention for any unusual or heavy bleeding, or a serious fall or head injury
  • Carry an anticoagulant alert card or wear medical identification if advised by your doctor
  • Ask your doctor or pharmacist for specific guidance if you miss a dose – do not simply double the next dose

Ingredients / Active Ingredients

  • Edoxaban 60mg (as edoxaban tosilate)

Frequently Asked Questions

Product Specifications

BrandA. Menarini
ClassificationPrescription medicine
Pack Size28s
Shelf LifeUse this product before the expiry date stated on the packaging. Do not use the medicine if the expiry date has passed.

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