Motigut 1mg/ml Suspension

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Dr. Mohd Izzat Amir Bin Awang
Reviewed byDr. Mohd Izzat Amir Bin AwangDoctor of Medicine (MD), University of Mansoura - Manchester
Dr. Adeline Carol Peters
Written byDr. Adeline Carol PetersBachelor of Medicine and Bachelor of Surgery (MBBS) — Manipal Academy of Higher Education (MAHE)

Last updated:

Overview

Motigut 1mg/ml Suspension is a prescription-only medicine (POM) presented as an oral suspension, with Domperidone 1mg/ml as its active ingredient content.

This page is limited to product, safety and handling information, in line with Malaysian rules on prescription medicine information for the public. Your prescriber or pharmacist is the right source for anything beyond that, together with the leaflet inside the pack.

Through DoctorOnCall, this product is supplied after an online consultation with a licensed doctor and a valid prescription, and it is checked by a registered pharmacist before dispensing. Take it exactly as prescribed, and speak to your doctor before stopping, changing the dose, or starting any other medicine alongside it.

Directions for Use

Shake the bottle well before each use. Measure the prescribed dose accurately using the oral syringe or measuring cup provided; do not use a regular kitchen spoon. Take the measured dose before meals, and before bedtime if your doctor has prescribed a bedtime dose, to help relieve nausea and digestive discomfort.

Dosage

The usual adult dose of domperidone is generally taken up to three times a day, and total daily intake normally should not exceed 30mg. Because of a small risk of heart rhythm effects with higher doses or longer use, your doctor will prescribe the lowest dose that controls your symptoms, for the shortest duration needed, and will usually reassess you if treatment with Motigut 1mg/ml Suspension is required for longer than about one week.

Storage Instructions

Store below 30°C in a dry place, away from direct sunlight and out of reach of children.

Side Effects

  • Dry mouth
  • Headache
  • Drowsiness
  • Stomach cramps
  • Feeling dizzy or light-headed
  • Changes in menstrual periods
  • Breast tenderness or swelling

Contraindications

  • Known hypersensitivity to domperidone or any ingredient in this product
  • A prolactin-releasing tumour of the pituitary gland (prolactinoma)
  • Conditions where increasing stomach and gut movement could be harmful, such as gastrointestinal bleeding, mechanical obstruction, or perforation
  • Moderate to severe liver impairment
  • Concurrent use with medicines known to significantly prolong the heart’s QT interval, or with strong CYP3A4 inhibitors

Drug / Food Interactions

  • Strong CYP3A4 inhibitors such as ketoconazole, erythromycin, and clarithromycin increase domperidone blood levels and heart rhythm risk
  • Other medicines that prolong the QT interval (certain antiarrhythmics, antipsychotics, or antimalarials) increase the risk of an irregular heartbeat when combined
  • Grapefruit juice may increase domperidone blood levels
  • Acid-reducing medicines that raise stomach pH may reduce domperidone absorption if taken at the same time

Quick Tips

  • Take at the lowest effective dose for the shortest time your doctor recommends
  • Take before meals, and before bedtime if prescribed, for the best effect on digestion
  • Tell your doctor about any heart problems or other medicines you take before starting this medicine
  • Seek urgent care for palpitations, dizziness, or fainting while taking this medicine
  • Do not continue this medicine for longer than your doctor has advised without a follow-up review
  • Check the expiry date before each use and discard any unused portion as instructed

Ingredients / Active Ingredients

  • Domperidone 1mg/ml

Safety Advice

Pregnancy

Safe If Prescribed

This medicine should only be used during pregnancy if prescribed by a doctor after careful evaluation.

Breastfeeding

Use With Care

Use with caution. Monitor infant for potential adverse reactions.

Kidney

Use With Care

Use cautiously. Dose adjustment or monitoring may be required.

Liver

Not Safe

This medicine is not safe for patients with liver problems.

Alcohol

Not Advisable

It is not advisable to consume alcohol while taking this medicine.

Driving

Generally Safe

This medicine is generally safe and should not impair your driving ability.

Frequently Asked Questions

Product Specifications

BrandSquare Pharma
ClassificationPrescription medicine
Ingredients / Active IngredientsDomperidone
Volume60ml
Shelf LifeUse this product before the expiry date stated on the packaging. Do not use the medicine if the expiry date has passed.

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