Do I need a prescription to buy Mydfrin 2.5% Solution?

No. Mydfrin 2.5% Solution is a non-prescription product and can be ordered without a prescription. It is still dispensed by a registered pharmacist on DoctorOnCall.

What does Mydfrin 2.5% Solution contain?

Mydfrin 2.5% Solution is a solution containing Phenylephrine Hydrochloride 2.5%. The full ingredient list is shown in the Composition or Ingredients section on this page and on the product packaging.

What pack sizes does Mydfrin 2.5% Solution come in?

It is supplied in a pack size of 5ml. Choose the pack size you need from the options shown on this page before adding the item to your cart.

Why is there no information here about what Mydfrin 2.5% Solution is for?

This page is limited to product, safety and handling information in line with Malaysian rules on medicine information. If you want advice on whether this product suits you, book an online consultation with a doctor or pharmacist on DoctorOnCall.

How should I use Mydfrin 2.5% Solution?

Follow the instructions printed on the label and in the leaflet supplied with the pack, and do not exceed the stated amount or duration. Handling steps are set out in the Directions for Use section on this page.

Can I speak to a doctor or pharmacist about Mydfrin 2.5% Solution before I buy it?

Yes. DoctorOnCall offers online consultations with licensed doctors and registered pharmacists, so you can ask about this product, your existing medicines, or anything on the label before you place an order.

How should I store Mydfrin 2.5% Solution?

Store below 30°C in a cool, dry place away from direct sunlight, and keep it out of reach of children. Keep the product in its original pack and do not use it after the printed expiry date.

What should I do if I notice side effects after using Mydfrin 2.5% Solution?

Stop using the product and speak to a doctor or pharmacist about any reaction that concerns you. Seek medical care immediately for signs of a severe reaction such as difficulty breathing, swelling of the face, lips or throat, or a widespread rash. Reported reactions are listed in the Side Effects section on this page.

How long will delivery take?

Within Malaysia, standard delivery takes 3 to 5 working days. Same-day delivery is available in the Klang Valley for orders placed before 12pm; orders placed after 12pm arrive by the end of the next day. Orders to Singapore are sent as international deliveries and take 5 to 9 working days. A lump-sum shipping and handling fee applies to every overseas delivery and is shown at checkout.

What payment methods can I use?

Customers in Malaysia can pay by FPX online banking, credit or debit card (Visa and Mastercard), and supported e-wallets including Touch ‘n Go eWallet, GrabPay and ShopeePay. FPX and local e-wallets are tied to Malaysian bank and wallet accounts, so if your delivery address is in Singapore, use the payment options displayed at checkout for that address rather than assuming the same list applies.

Can Mydfrin 2.5% Solution be delivered to Singapore?

Yes. DoctorOnCall ships to Singapore as an international order dispatched from Malaysia, arriving in 5 to 9 working days with a lump-sum shipping and handling fee. Singapore’s Health Sciences Authority (HSA) allows personal imports of up to three months’ supply of a medicine for your own use or an immediate family member’s, as long as it contains no controlled drugs, psychotropic substances or prohibited items. Keep the product in its original labelled packaging and keep a copy of your prescription or doctor’s letter with it. Quantities above three months’ supply, and medicines containing controlled substances, require prior HSA approval.

Is Mydfrin 2.5% Solution registered with the authorities?

Products listed on DoctorOnCall are registered with Malaysia’s Ministry of Health for supply in Malaysia, and each pack carries its MAL registration number. An order delivered to Singapore arrives as a personal import of a Malaysia-registered product; HSA product registration is not required for personal-use quantities, but it is also not the same as a product registered for sale in Singapore. If you need a locally registered Singapore product, buy it from a pharmacy in Singapore.

Who do I contact if there is a problem with my order?

DoctorOnCall’s customer care team handles order, delivery and product queries through the contact channels on the site, including WhatsApp and the online help centre. For deliveries to Singapore, allow more time before chasing an order than you would for a local Malaysian delivery, as the parcel passes through customs clearance and tracking updates can appear later in the journey.

Mydfrin 2.5% Solution | phenylephrine | eye dilation diagnostic drop | DoctorOnCall Malaysia

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Reviewed byDr. Mohd Izzat Amir Bin AwangDoctor of Medicine (MD), University of Mansoura - Manchester

Written byDr. Adeline Carol PetersBachelor of Medicine and Bachelor of Surgery (MBBS) — Manipal Academy of Higher Education (MAHE)

Last updated: October 18, 2026

Overview

Mydfrin 2.5% Solution is supplied as a solution, with Phenylephrine Hydrochloride 2.5%. It is supplied in a pack size of 5ml.

No prescription is required for this product, as it is a non-prescription medicine. This page is limited to product, safety and handling information.

If you would like guidance before buying, you can speak to a doctor or pharmacist through an online consultation on DoctorOnCall. Orders are dispensed by a registered pharmacist and delivered to your address.

Directions for Use

Mydfrin 2.5% Solution is administered by, or under the direct supervision of, an eye care professional. Typically, one drop is instilled into the lower conjunctival sac of the eye being examined, with any excess solution gently blotted away with a clean tissue. Light pressure on the inner corner of the eye (punctal occlusion) for about a minute after instillation is often used to reduce the amount of drug absorbed into the general circulation. This medicine should not be self-administered outside a clinical setting without a doctor’s specific instruction.

Dosage

The usual clinical dose is one drop of Mydfrin 2.5% Solution instilled into the eye approximately 15 to 30 minutes before the examination or procedure requiring dilation, with a second drop sometimes given if the pupil has not dilated sufficiently. The exact dose, frequency, and whether the lower-strength 2.5% (rather than 10%) formulation is used depends on the patient’s age, cardiovascular health, and the judgement of the administering doctor or ophthalmologist, and should never be adjusted without medical advice.

Shelf Life

Unopened, Mydfrin 2.5% Solution is generally stable until the expiry date printed on the bottle and outer carton. Once opened, ophthalmic solutions such as this are typically recommended for use within about 4 weeks, after which any remaining solution should be discarded even if the printed expiry date has not yet passed, as sterility cannot be guaranteed beyond that point.

Storage Instructions

Store Mydfrin 2.5% Solution below 25°C, away from direct sunlight and heat, and keep the bottle tightly closed between uses. Do not freeze. Keep out of reach and sight of children, and avoid letting the dropper tip touch the eye, fingers, or any other surface to prevent contamination of the remaining solution.

Side Effects

Headache
Dizziness
Nervousness or restlessness
Increased blood pressure
Rapid heartbeat (palpitations)
Trouble sleeping (especially if taken at night)

Contraindications

Known hypersensitivity to phenylephrine or any other ingredient in the solution
Narrow-angle or angle-closure glaucoma, or a narrow anterior chamber angle
Uncontrolled high blood pressure or significant cardiovascular disease
Use in infants and young children without specific medical supervision, due to higher sensitivity to systemic effects
Concurrent use with certain monoamine oxidase inhibitors (MAOIs) unless specifically directed by a doctor

Drug / Food Interactions

Monoamine oxidase inhibitors (MAOIs), which can dangerously potentiate phenylephrine’s effect on blood pressure
Tricyclic antidepressants and other drugs that enhance sympathomimetic activity
Beta-blockers and other blood pressure or heart-rhythm medications, due to possible additive cardiovascular effects
Other mydriatic or sympathomimetic eye drops used in the same session, which may increase systemic absorption

Quick Tips

Arrange for someone to drive you home after your appointment, as vision will be blurred and light-sensitive for several hours
Bring sunglasses to wear after your eyes have been dilated
Tell your doctor about any heart conditions, high blood pressure, or glaucoma before this drop is used
Do not rub your eyes or touch the dropper tip to any surface
Attend any follow-up review your doctor recommends after the examination

Ingredients / Active Ingredients

Phenylephrine

Phenylephrine Hydrochloride 2.5% (active ingredient)
Benzalkonium Chloride (preservative)
Boric Acid
Sodium Citrate
Hydrochloric Acid and/or Sodium Hydroxide (for pH adjustment)
Purified Water

Safety Advice

Pregnancy

Safe If Prescribed

This medicine should only be used during pregnancy if prescribed by a doctor after careful evaluation.

Breastfeeding

Use With Care

Use with caution. Monitor infant for potential adverse reactions.

Kidney

Use With Care

Use cautiously. Dose adjustment or monitoring may be required.

Liver

Use With Care

Use cautiously. Liver function monitoring may be required.

Alcohol

Use With Care

Caution is advised when consuming alcohol with this medicine.

Driving

Use With Care

Use caution while driving until you know how this medicine affects you.

Relevant Information

Mydfrin 2.5% Solution is intended for use in a clinical or pharmacist-supervised setting rather than for routine home use, and DoctorOnCall requires an online medical consultation before it is dispensed so that a doctor can confirm the indication, check for contraindications such as glaucoma or uncontrolled heart disease, and advise on safe administration.