Onglyza 5mg Tablet
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Overview
Onglyza 5mg Tablet contains saxagliptin 5mg, a dipeptidyl peptidase-4 (DPP-4) inhibitor used together with diet and exercise to improve blood sugar control in adults with type 2 diabetes mellitus. It may be used alone or in combination with other diabetes medicines such as metformin.
Saxagliptin works by blocking the DPP-4 enzyme, which normally breaks down incretin hormones released after meals. By preserving these hormones, saxagliptin increases insulin release and reduces glucagon release in a glucose-dependent manner, helping to lower blood sugar mainly after meals.
How it Works
Saxagliptin inhibits the DPP-4 enzyme, prolonging the activity of the incretin hormones GLP-1 and GIP. These hormones stimulate the pancreas to release more insulin and suppress excess glucagon release when blood sugar is high, an effect that diminishes as blood sugar approaches normal, which keeps the risk of low blood sugar relatively low when used alone.
Directions for Use
Take Onglyza 5mg Tablet once daily, at about the same time each day, with or without food. Swallow the tablet whole with a glass of water. Continue regular blood sugar monitoring and medical check-ups as advised by your doctor, as this medicine works best alongside a healthy diet and regular physical activity.
Dosage
The usual dose of Onglyza 5mg Tablet is 5mg once daily, taken with or without food. Your doctor may prescribe a lower dose of 2.5mg once daily if you have moderate to severe kidney impairment or are taking certain other medicines. Do not change your dose without consulting your doctor, and continue following the diet and exercise plan you have been given.
Shelf Life
Use this product before the expiry date stated on the packaging. Do not use the medicine if the expiry date has passed.
Storage Instructions
Store below 30°C in a dry place, away from direct sunlight and out of reach of children.
Side Effects
- Headache
- Upper respiratory tract infection
- Nasal congestion or sore throat
- Urinary tract infection
- Joint pain
- Diarrhea
- Nausea
- Fatigue
Contraindications
- Known hypersensitivity to saxagliptin or any ingredient in this product
- History of a serious hypersensitivity reaction (e.g. angioedema, anaphylaxis) to saxagliptin or another DPP-4 inhibitor
- Type 1 diabetes mellitus or diabetic ketoacidosis
- Not recommended in patients with heart failure without careful assessment by a doctor
Drug / Food Interactions
- Strong CYP3A4/5 inhibitors (e.g. ketoconazole, ritonavir, clarithromycin) significantly increase saxagliptin levels and usually require a lower dose
- Strong CYP3A4/5 inducers (e.g. rifampicin) can reduce saxagliptin’s effectiveness
- Sulfonylureas (e.g. glimepiride) or insulin combined with saxagliptin increase the risk of low blood sugar (hypoglycaemia)
- No clinically significant interaction with food, so it can be taken with or without meals
Quick Tips
- Take at the same time every day to help control blood sugar consistently
- Watch for and report signs of low blood sugar if you also take a sulfonylurea or insulin
- Seek medical attention promptly for severe or persistent stomach pain
- Attend your scheduled blood sugar and kidney function tests
Frequently Asked Questions
What is Onglyza 5mg Tablet used for?
Onglyza 5mg Tablet is used, alongside diet and exercise, to help control blood sugar levels in adults with type 2 diabetes. It may be used alone or together with other diabetes medicines as prescribed by your doctor.
Can this medicine cause low blood sugar (hypoglycaemia) on its own?
Used alone, saxagliptin has a relatively low risk of causing low blood sugar because it works in a glucose-dependent way. The risk increases if it is combined with a sulfonylurea or insulin.
Does this medicine treat type 1 diabetes?
No, saxagliptin is only for type 2 diabetes and must not be used for type 1 diabetes or diabetic ketoacidosis.
What symptoms of pancreatitis should I watch for?
Seek medical attention promptly if you develop severe, persistent abdominal pain, which may or may not spread to your back, with or without nausea and vomiting, as this can be a sign of pancreatitis.
What should I do if I miss a dose of Onglyza 5mg Tablet?
Take the missed dose as soon as you remember, unless it is almost time for your next dose – in that case, skip the missed dose and continue your regular schedule. Do not double the dose.
Can I buy Onglyza 5mg Tablet from DoctorOnCall?
Yes, Onglyza 5mg Tablet is available through DoctorOnCall, a licensed online pharmacy serving our Malaysian and Singaporean customers. As this is a prescription medicine, you will need to complete an online consultation so a doctor can assess your suitability and issue a valid prescription before the order is processed. This ensures the medicine is appropriate for your condition and used under proper medical supervision, whether you are ordering from Malaysia or Singapore.
Is the medication provided by DoctorOnCall genuine and safe to use?
DoctorOnCall sources its medicines through appropriate licensed pharmacy supply channels for our Malaysian and Singaporean customers. All orders are dispensed and checked by a registered pharmacist before delivery. Always use Onglyza 5mg Tablet according to your doctor’s instructions and the information provided with the product.
What payment methods does DoctorOnCall accept?
We accept payment via Online Banking, Credit Card, and e-Wallets (Boost, GrabPay) for our Malaysian and Singaporean customers, so you can choose whichever method is most convenient for you at checkout.
Does DoctorOnCall provide an installment payment plan for Onglyza 5mg Tablet?
DoctorOnCall provides an installment payment plan for eligible Malaysian and Singaporean customers, where applicable. Available plans, eligibility, and terms can vary by market, so please contact DoctorOnCall Customer Service for the latest information on installment options for your order.
Is delivery free, and how much does shipping for Onglyza 5mg Tablet cost?
Delivery charges may vary for our Malaysian and Singaporean customers depending on your delivery location and the applicable order terms at the time of purchase. For the most accurate and up-to-date delivery fee information, please contact DoctorOnCall Customer Service before placing your order.
How long does delivery take for Onglyza 5mg Tablet?
Our Malaysian customers can generally expect delivery within 3-5 working days, while our Singaporean customers generally receive their orders within 5-7 working days. These are expected timeframes rather than guarantees, and actual delivery time may vary depending on your delivery location, order processing time, courier operations, and whether the order falls on a weekend or public holiday.
What is DoctorOnCall’s shipping, return, or cancellation policy for Onglyza 5mg Tablet?
Shipping, return, and cancellation terms may vary for our Malaysian and Singaporean customers depending on the product and your order details. Please refer to DoctorOnCall’s Shipping & Delivery Policy and Return, Refund & Exchange Policy, or contact Customer Service, for the specific terms that apply to your order.
Ingredients / Active Ingredients
- Saxagliptin 5mg (as saxagliptin hydrochloride)
Safety Advice
Pregnancy
This medicine should be used cautiously during pregnancy. Monitoring may be required.
Breastfeeding
Use with caution. Monitor infant for potential adverse reactions.
Kidney
Use cautiously. Dose adjustment or monitoring may be required.
Liver
Use cautiously. Liver function monitoring may be required.
Alcohol
Caution is advised when consuming alcohol with this medicine.
Driving
Use caution while driving until you know how this medicine affects you.
Medical Review
