Oroxine 100mcg Tablet

Brand Aspen
Manufacturer Aspen
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Dr. Mohd Izzat Amir Bin Awang
Reviewed byDr. Mohd Izzat Amir Bin AwangDoctor of Medicine (MD), University of Mansoura - Manchester
Dr. Adeline Carol Peters
Written byDr. Adeline Carol PetersBachelor of Medicine and Bachelor of Surgery (MBBS) — Manipal Academy of Higher Education (MAHE)

Last updated:

Overview

Oroxine 100mcg Tablet is supplied as a tablet, with Levothyroxine Sodium, equivalent to 100mcg levothyroxine. It is supplied in a pack size of 100s.

No prescription is required for this product, as it is a non-prescription medicine. This page is limited to product, safety and handling information.

If you would like guidance before buying, you can speak to a doctor or pharmacist through an online consultation on DoctorOnCall. Orders are dispensed by a registered pharmacist and delivered to your address.

Directions for Use

Take Oroxine on an empty stomach, generally 30 to 60 minutes before breakfast, with a full glass of water, unless your doctor advises otherwise. Take it at the same time every day and avoid taking it together with calcium or iron supplements, antacids, or certain other medicines, as these can reduce absorption; space these apart by at least 4 hours. Do not change your dose or stop the medicine on your own, even if you feel well, since hypothyroidism requires ongoing treatment and dose adjustments should only be made after your doctor reviews your blood test results.

Dosage

The dose is individualised by your doctor based on your age, weight, the cause and severity of your hypothyroidism, and periodic thyroid function blood test results; this 100mcg strength is often reached after a gradual step-up from a lower starting dose, or used as an initial dose in patients who need a larger amount of replacement hormone. Because it usually takes several weeks for a dose change to be reflected in blood tests and symptoms, do not adjust your dose yourself between scheduled reviews.

Shelf Life

Use Oroxine tablets before the expiry date printed on the blister strip or carton. Do not use the tablets after this date, and dispose of any unused or expired tablets appropriately rather than keeping them for future use.

Storage Instructions

Store below 25 degrees Celsius, in a cool, dry place away from direct sunlight and moisture, in the original packaging until ready to use. Keep out of reach and sight of children.

Side Effects

  • Headache
  • Nervousness or anxiety
  • Sleeplessness (insomnia)
  • Increased appetite
  • Weight loss
  • Sweating
  • Palpitations or rapid heartbeat
  • Menstrual irregularities

Contraindications

  • Untreated adrenal insufficiency or untreated overactive pituitary/adrenal conditions
  • Untreated thyrotoxicosis (an overactive thyroid)
  • Acute, untreated heart attack (myocardial infarction)
  • Known hypersensitivity to levothyroxine or any tablet ingredient
  • Should be used with particular caution and close monitoring at this higher strength in people with heart disease, arrhythmia history, diabetes, osteoporosis, or in older adults, where doctors often prefer a slower, more gradual dose increase

Drug / Food Interactions

  • Calcium supplements, iron supplements, and antacids containing aluminium or magnesium can reduce levothyroxine absorption; space these apart from your dose by at least 4 hours
  • Certain foods and supplements, such as high-fibre meals, soy products, and coffee taken close to dosing, can reduce absorption
  • May increase the effect of blood-thinning medicines such as warfarin, requiring closer monitoring, particularly important at higher levothyroxine doses
  • Can alter blood sugar control in people with diabetes, sometimes requiring adjustment of diabetes medicines
  • Certain seizure medicines and rifampicin can affect levothyroxine levels; inform your doctor of all medicines you take

Quick Tips

  • Take Oroxine at the same time each day, ideally on an empty stomach before breakfast, for consistent absorption
  • Keep at least a 4-hour gap between this medicine and calcium, iron, or antacid products
  • Attend all scheduled blood tests so your doctor can monitor and fine-tune this higher-strength dose appropriately
  • Do not stop treatment on your own, even if you feel well, as hypothyroidism symptoms can return
  • Report new palpitations, chest pain, tremor or unusual sweating to your doctor promptly, as these can signal the dose needs reviewing
  • Let your doctor know if you become pregnant, as thyroid hormone needs often increase during pregnancy

Ingredients / Active Ingredients

  • Active ingredient: Levothyroxine Sodium, equivalent to 100mcg levothyroxine
  • Microcrystalline cellulose
  • Lactose monohydrate
  • Croscarmellose sodium
  • Magnesium stearate
  • Colouring and other standard tablet excipients

Safety Advice

Pregnancy

Safe If Prescribed

This medicine should only be used during pregnancy if prescribed by a doctor after careful evaluation.

Breastfeeding

Generally Safe

This medicine is generally safe during breastfeeding with minimal risk to the infant.

Kidney

Use With Care

Use cautiously. Dose adjustment or monitoring may be required.

Liver

Safe If Prescribed

Use only if prescribed, with possible monitoring.

Alcohol

Use With Care

Caution is advised when consuming alcohol with this medicine.

Driving

Generally Safe

This medicine is generally safe and should not impair your driving ability.

Relevant Information

Hypothyroidism usually requires lifelong hormone replacement, and reaching the correct maintenance dose, such as this 100mcg strength, is often achieved through gradual dose increases guided by regular thyroid function blood tests. Getting the dose right matters because both under-treatment and over-treatment can cause noticeable symptoms and, over time, affect the heart and bone health, which is why levothyroxine remains a prescription-only medicine at every strength. Customers in Malaysia and Singapore should use DoctorOnCall’s online consultation service to obtain and renew their levothyroxine prescription and should keep up with periodic blood test monitoring as advised by their doctor, particularly if their dose has recently changed.

Frequently Asked Questions

Product Specifications

BrandAspen
ManufacturerAspen
ClassificationNon-prescription
Ingredients / Active IngredientsLevothyroxine
Pack Size100s

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Important Medical Information

💊 Recommended Dosage:

The dose is individualised by your doctor based on your age, weight, the cause and severity of your hypothyroidism, and periodic thyroid function blood test results; this 100mcg strength is often reached after a gradual step-up from a lower starting dose, or used as an initial dose in patients who need a larger amount of replacement hormone. Because it usually takes several weeks for a dose change to be reflected in blood tests and symptoms, do not adjust your dose yourself between scheduled reviews.

🛑 Contraindications (Do not use if):
  • Untreated adrenal insufficiency or untreated overactive pituitary/adrenal conditions
  • Untreated thyrotoxicosis (an overactive thyroid)
  • Acute, untreated heart attack (myocardial infarction)
  • Known hypersensitivity to levothyroxine or any tablet ingredient
  • Should be used with particular caution and close monitoring at this higher strength in people with heart disease, arrhythmia history, diabetes, osteoporosis, or in older adults, where doctors often prefer a slower, more gradual dose increase
If you are unsure, please chat with us or consult your doctor.
⚠️ Common Side Effects:
  • Headache
  • Nervousness or anxiety
  • Sleeplessness (insomnia)
  • Increased appetite
  • Weight loss
  • Sweating
  • Palpitations or rapid heartbeat
  • Menstrual irregularities
Stop taking this medication immediately and consult your doctor if you experience severe allergic reactions or side effects.
IMPORTANT: Unsure? Chat with our pharmacists (Mon - Sat, 9:00am - 6:00pm) before buying.