Pravafen 40/160mg Capsule

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Dr. Mohd Izzat Amir Bin Awang
Reviewed byDr. Mohd Izzat Amir Bin AwangDoctor of Medicine (MD), University of Mansoura - Manchester
Dr. Adeline Carol Peters
Written byDr. Adeline Carol PetersBachelor of Medicine and Bachelor of Surgery (MBBS) — Manipal Academy of Higher Education (MAHE)

Last updated:

Overview

Pravafen 40/160mg Capsule is a prescription-only medicine (POM) presented as a capsule, with Pravastatin sodium 40mg and Fenofibrate 160mg as its active ingredient content.

This page is limited to product, safety and handling information, in line with Malaysian rules on prescription medicine information for the public. Your prescriber or pharmacist is the right source for anything beyond that, together with the leaflet inside the pack.

Through DoctorOnCall, this product is supplied after an online consultation with a licensed doctor and a valid prescription, and it is checked by a registered pharmacist before dispensing. Take it exactly as prescribed, and speak to your doctor before stopping, changing the dose, or starting any other medicine alongside it.

Directions for Use

Take Pravafen 40/160mg Capsule once daily with food, as food improves the absorption of the fenofibrate component, and swallow the capsule whole with water.

Dosage

Pravafen 40/160mg Capsule is usually taken once daily as directed by your doctor, who will confirm this combination is suitable for you based on your lipid profile and kidney function. Periodic monitoring of your lipid levels and liver function is required while on treatment.

Storage Instructions

Store below 30°C in a dry place, away from direct sunlight and out of reach of children.

Side Effects

  • Headache
  • Stomach pain
  • Nausea or vomiting
  • Muscle pain or weakness
  • Tiredness
  • Skin rash or itching
  • Mild diarrhea

Contraindications

  • Known hypersensitivity to pravastatin, fenofibrate, or any ingredient in this product
  • Active liver disease
  • Severe kidney impairment
  • Gallbladder disease
  • Pregnancy and breastfeeding
  • Unexplained, persistent elevation of creatine kinase (CK)

Drug / Food Interactions

  • Cyclosporine and certain protease inhibitors can increase statin levels and further raise the risk of muscle toxicity
  • Other fibrates or high-dose niacin further increase the risk of myopathy when combined with this product
  • Warfarin’s blood-thinning effect may be potentiated by fenofibrate, requiring closer INR monitoring
  • Bile acid resins (e.g. cholestyramine) may reduce absorption if taken at the same time – space doses apart

Quick Tips

  • Report any unexplained muscle pain, tenderness, weakness, or dark urine to your doctor promptly – this combination of a statin and a fibrate carries a higher risk of muscle-related side effects than either medicine used alone
  • Attend all scheduled blood tests to monitor your lipid levels, liver function, and kidney function
  • Take with food to support absorption of the fenofibrate component
  • Avoid excessive alcohol intake, which can add to the risk of liver-related side effects

Ingredients / Active Ingredients

  • Pravastatin sodium 40mg
  • Fenofibrate 160mg

Safety Advice

Pregnancy

Safe If Prescribed

This medicine should only be used during pregnancy if prescribed by a doctor after careful evaluation.

Breastfeeding

Not Safe

This medicine is not safe during breastfeeding and should be avoided.

Kidney

Use With Care

Use cautiously. Dose adjustment or monitoring may be required.

Liver

No Data

No adequate data available. Consult a doctor before use.

Alcohol

Not Advisable

It is not advisable to consume alcohol while taking this medicine.

Driving

Not Advisable

It is not advisable to drive if you experience side effects from this medicine.

Frequently Asked Questions

Product Specifications

BrandHyphens
ClassificationPrescription medicine
Ingredients / Active IngredientsFenofibrate
Pack Size30s
Shelf LifeUse this product before the expiry date stated on the packaging. Do not use the medicine if the expiry date has passed.

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