Protopic 0.03% Ointment

Brand LEO
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Overview

Protopic 0.03% Ointment contains Tacrolimus (as tacrolimus monohydrate) 0.03% w/w and is presented as an ointment. It is supplied in a pack size of 10g.

It is classified as a non-prescription medicine, so no prescription is needed to order it. Under Malaysian rules for medicine information, this page carries product, safety and handling information only.

You can consult a doctor or pharmacist online on DoctorOnCall about this product before or after you order. Every order is checked by a registered pharmacist before it is delivered. Always read the label and the leaflet supplied with the pack.

Directions for Use

Apply a thin layer of Protopic 0.03% Ointment to the affected areas of skin twice daily as directed by your doctor, gently rubbing it in until fully absorbed, and continue until the skin clears; your doctor may then advise reducing to a maintenance regimen, and hands should be washed after application unless the hands themselves are the treated area.

Dosage

The typical dose for children aged 2 to 15 years, and for adults using the lower-strength maintenance regimen, is a thin layer of Protopic 0.03% Ointment applied twice daily to affected areas until clearance, with your doctor guiding any adjustment for maintenance therapy; do not apply more often or in a thicker layer than prescribed.

Shelf Life

Protopic 0.03% Ointment is generally stable for around 2 to 3 years from the date of manufacture when unopened, so always check the expiry date printed on the tube or carton before use.

Storage Instructions

Store Protopic 0.03% Ointment below 25°C to 30°C in a dry place away from direct sunlight, and keep it out of the sight and reach of children when not being applied by a caregiver.

Side Effects

  • Headache
  • Nausea or vomiting
  • Increased blood sugar levels
  • Risk of infections
  • Tremors or shakiness
  • High blood pressure
  • Fatigue or weakness
  • Skin irritation (with topical use)

Contraindications

  • Known hypersensitivity to tacrolimus or any other ingredient in the ointment
  • Use on skin with an active, untreated bacterial, viral, or fungal infection
  • Children under 2 years of age, unless specifically directed by a paediatrician
  • Use under occlusive dressings or bandages unless specifically advised by your doctor
  • Conditions associated with a weakened immune system, or Netherton’s syndrome, without specific doctor approval, due to increased systemic absorption risk

Drug / Food Interactions

  • Alcohol may cause facial flushing or skin warmth in adult users when combined with Protopic 0.03% Ointment
  • Concurrent use of other topical treatments on the same area should only be done under medical advice
  • Phototherapy (UV light treatment) is not recommended while using tacrolimus, as combined use may increase skin cancer risk
  • Live vaccines should be discussed with your doctor before administration during treatment

Quick Tips

  • Apply only a thin layer — more product does not improve results and may increase side effects
  • Protect treated skin from strong sun exposure with sunscreen or protective clothing, as tacrolimus can increase photosensitivity
  • Avoid occlusive dressings or bandages over treated skin unless directed by your doctor
  • Do not apply to skin with active infection until it has been treated and cleared
  • Attend follow-up appointments, especially for children, so your doctor can monitor growth and skin response over time
  • Caregivers should wash their hands after applying the ointment to a child unless their own hands are the treated area

Frequently Asked Questions

Do I need a prescription to buy Protopic 0.03% Ointment?

No. Protopic 0.03% Ointment is a non-prescription product and can be ordered without a prescription. It is still dispensed by a registered pharmacist on DoctorOnCall.

What does Protopic 0.03% Ointment contain?

Protopic 0.03% Ointment is an ointment containing Tacrolimus (as tacrolimus monohydrate) 0.03% w/w. The full ingredient list is shown in the Composition or Ingredients section on this page and on the product packaging.

What pack sizes does Protopic 0.03% Ointment come in?

It is supplied in a pack size of 10g. Choose the pack size you need from the options shown on this page before adding the item to your cart.

Why is there no information here about what Protopic 0.03% Ointment is for?

This page is limited to product, safety and handling information in line with Malaysian rules on medicine information. If you want advice on whether this product suits you, book an online consultation with a doctor or pharmacist on DoctorOnCall.

How should I use Protopic 0.03% Ointment?

Use it exactly as stated on the pack label, without changing the amount or how often you use it. If anything on the label is unclear, check with a pharmacist before the first use, and read the Directions for Use section on this page.

Can I speak to a doctor or pharmacist about Protopic 0.03% Ointment before I buy it?

Yes. DoctorOnCall offers online consultations with licensed doctors and registered pharmacists, so you can ask about this product, your existing medicines, or anything on the label before you place an order.

How should I store Protopic 0.03% Ointment?

Store Protopic 0.03% Ointment below 25°C to 30°C in a dry place away from direct sunlight, and keep it out of the sight and reach of children when not being applied by a caregiver. Keep it in its original pack and do not use it after the expiry date printed on the packaging.

What should I do if I notice side effects after using Protopic 0.03% Ointment?

Stop using the product and speak to a doctor or pharmacist about any reaction that concerns you. Seek medical care immediately for signs of a severe reaction such as difficulty breathing, swelling of the face, lips or throat, or a widespread rash. Reported reactions are listed in the Side Effects section on this page.

How long will delivery take?

Within Malaysia, standard delivery takes 3 to 5 working days. Same-day delivery is available in the Klang Valley for orders placed before 12pm; orders placed after 12pm arrive by the end of the next day.

Orders to Singapore are sent as international deliveries and take 5 to 9 working days. A lump-sum shipping and handling fee applies to every overseas delivery and is shown at checkout.

What payment methods can I use?

Customers in Malaysia can pay by FPX online banking, credit or debit card (Visa and Mastercard), and supported e-wallets including Touch ‘n Go eWallet, GrabPay and ShopeePay.

FPX and local e-wallets are tied to Malaysian bank and wallet accounts, so if your delivery address is in Singapore, use the payment options displayed at checkout for that address rather than assuming the same list applies.

Can Protopic 0.03% Ointment be delivered to Singapore?

Yes. DoctorOnCall ships to Singapore as an international order dispatched from Malaysia, arriving in 5 to 9 working days with a lump-sum shipping and handling fee.

Singapore’s Health Sciences Authority (HSA) allows personal imports of up to three months’ supply of a medicine for your own use or an immediate family member’s, as long as it contains no controlled drugs, psychotropic substances or prohibited items. Keep the product in its original labelled packaging and keep a copy of your prescription or doctor’s letter with it. Quantities above three months’ supply, and medicines containing controlled substances, require prior HSA approval.

Is Protopic 0.03% Ointment registered with the authorities?

Products listed on DoctorOnCall are registered with Malaysia’s Ministry of Health for supply in Malaysia, and each pack carries its MAL registration number.

An order delivered to Singapore arrives as a personal import of a Malaysia-registered product; HSA product registration is not required for personal-use quantities, but it is also not the same as a product registered for sale in Singapore. If you need a locally registered Singapore product, buy it from a pharmacy in Singapore.

Who do I contact if there is a problem with my order?

DoctorOnCall’s customer care team handles order, delivery and product queries through the contact channels on the site, including WhatsApp and the online help centre.

For deliveries to Singapore, allow more time before chasing an order than you would for a local Malaysian delivery, as the parcel passes through customs clearance and tracking updates can appear later in the journey.

Ingredients / Active Ingredients

  • Tacrolimus (as tacrolimus monohydrate) 0.03% w/w
  • White soft paraffin
  • Paraffin oil
  • Propylene carbonate and other standard ointment excipients

Safety Advice

Pregnancy

Use With Care

This medicine should be used cautiously during pregnancy. Monitoring may be required.

Breastfeeding

Not Advisable

Generally not recommended while breastfeeding.

Kidney

Use With Care

Use cautiously. Dose adjustment or monitoring may be required.

Liver

Use With Care

Use cautiously. Liver function monitoring may be required.

Alcohol

Not Advisable

It is not advisable to consume alcohol while taking this medicine.

Driving

Not Advisable

It is not advisable to drive if you experience side effects from this medicine.

Relevant Information

Protopic 0.03% Ointment is the lower-strength option specifically studied and approved for children aged 2 years and above with moderate-to-severe eczema, and is also used in adults as a gentler maintenance treatment or for milder disease. Because it is a prescription immunomodulator used partly in a paediatric population, ongoing doctor follow-up — including monitoring of the child’s overall development — is an important part of safe treatment, and DoctorOnCall’s doctors remain available for review through further online consultations as needed.

Medical Review

Written by:

Dr. Chong Zhan Pong

Doctor of Medicine (MD), International Medical University (IMU)

Reviewed by:

Dr. Mohd Izzat Amir Bin Awang

Doctor of Medicine (MD), University of Mansoura - Manchester

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Important Medical Information

💊 Recommended Dosage:

The typical dose for children aged 2 to 15 years, and for adults using the lower-strength maintenance regimen, is a thin layer of Protopic 0.03% Ointment applied twice daily to affected areas until clearance, with your doctor guiding any adjustment for maintenance therapy; do not apply more often or in a thicker layer than prescribed.

🛑 Contraindications (Do not use if):
  • Known hypersensitivity to tacrolimus or any other ingredient in the ointment
  • Use on skin with an active, untreated bacterial, viral, or fungal infection
  • Children under 2 years of age, unless specifically directed by a paediatrician
  • Use under occlusive dressings or bandages unless specifically advised by your doctor
  • Conditions associated with a weakened immune system, or Netherton’s syndrome, without specific doctor approval, due to increased systemic absorption risk
If you are unsure, please chat with us or consult your doctor.
⚠️ Common Side Effects:
  • Headache
  • Nausea or vomiting
  • Increased blood sugar levels
  • Risk of infections
  • Tremors or shakiness
  • High blood pressure
  • Fatigue or weakness
  • Skin irritation (with topical use)
Stop taking this medication immediately and consult your doctor if you experience severe allergic reactions or side effects.
IMPORTANT: Unsure? Chat with our pharmacists (Mon - Sat, 9:00am - 6:00pm) before buying.