Sifrol 0.125mg Tablet

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Overview

Sifrol 0.125mg Tablet contains Pramipexole 0.125mg (immediate-release) and is available as a tablet. It is classified as a prescription medicine and may only be obtained with a valid prescription from a registered medical practitioner.

Only product, safety and handling information is published here. Anything beyond that is explained to you directly by your doctor or pharmacist as part of your consultation.

DoctorOnCall is a licensed online pharmacy. Orders for Sifrol 0.125mg Tablet are processed only after a doctor has assessed your suitability and issued a prescription, and every order is checked by a registered pharmacist before it is sent out.

Directions for Use

Take Sifrol 0.125mg Tablet with or without food, as prescribed, usually three times daily at evenly spaced intervals for Parkinson’s disease. Do not stop this medicine suddenly without your doctor’s advice, as abrupt withdrawal can cause withdrawal symptoms or, rarely, a fever and confusion resembling neuroleptic malignant syndrome.

Dosage

Treatment usually starts at a low dose and is gradually increased (titrated) over several weeks under close medical supervision, based on your response and tolerability, until an effective dose is reached. Your doctor will determine your specific starting dose, titration schedule, and maintenance dose.

Shelf Life

Use this product before the expiry date stated on the packaging. Do not use the medicine if the expiry date has passed.

Storage Instructions

Store below 30°C in a dry place, away from direct sunlight and out of reach of children.

Side Effects

  • Nausea or upset stomach
  • Drowsiness or dizziness
  • Headache
  • Dry mouth
  • Constipation
  • Hallucinations (rare but serious)
  • Swelling of arms or legs
  • Sudden sleep episodes

Contraindications

  • Known hypersensitivity to pramipexole or any component of this product
  • Use with caution in patients with severe kidney impairment (dose adjustment needed)
  • Use with caution in patients with a history of psychotic disorders

Drug / Food Interactions

  • Other dopaminergic medicines (e.g. levodopa) may enhance both effect and side effects
  • Antipsychotic medicines that block dopamine receptors may reduce the effectiveness of pramipexole
  • Sedating medicines or alcohol may increase drowsiness
  • Cimetidine may increase blood levels of pramipexole

Quick Tips

  • Be cautious about driving or operating machinery, as this medicine can cause sudden episodes of falling asleep without warning
  • Tell your doctor immediately if you or your family notice new compulsive behaviours such as gambling, shopping, or binge eating
  • Do not stop this medicine abruptly without medical advice
  • Rise slowly from sitting or lying down to reduce dizziness

Frequently Asked Questions

Is Sifrol 0.125mg Tablet a prescription medicine?

Yes. Sifrol 0.125mg Tablet is a prescription-only medicine (POM). It can only be supplied against a valid prescription written by a registered doctor, and it should be used only by the person named on the prescription label.

What does Sifrol 0.125mg Tablet contain?

Sifrol 0.125mg Tablet is supplied as a tablet and contains Pramipexole 0.125mg (immediate-release). The full composition is listed in the Composition section on this page and on the product packaging.

Why is there no information here about what Sifrol 0.125mg Tablet is for?

Malaysian rules for prescription medicines limit public product pages to product, safety and handling information. Your doctor decides whether this medicine is appropriate for you and will explain it during your consultation, and your pharmacist can answer further questions when the medicine is dispensed.

How should I take Sifrol 0.125mg Tablet?

Follow your doctor’s instructions and the directions on the dispensing label without changing them. If anything on the label is unclear, check with your pharmacist before taking the first dose, and read the Directions for Use section on this page.

What should I do if I miss a dose?

Take it as soon as you remember, unless your next dose is nearly due. In that case skip the missed dose and carry on with your usual schedule. Never take two doses together to make up for a missed one. If you miss doses often, tell your doctor or pharmacist.

How should I store Sifrol 0.125mg Tablet?

Store below 30°C in a dry place, away from direct sunlight and out of reach of children. Keep it in the original pack until use, and do not use it after the expiry date printed on the packaging.

What should I do if I notice side effects?

Tell your doctor or pharmacist about any reaction that concerns you, and seek medical care immediately for signs of a severe reaction such as difficulty breathing, swelling of the face, lips or throat, or a widespread rash. Reported reactions are listed in the Side Effects section on this page.

Can I stop taking Sifrol 0.125mg Tablet on my own?

No. Speak to your doctor before stopping, pausing or changing the dose, even if you feel well or think you no longer need the medicine.

How do I get a prescription for Sifrol 0.125mg Tablet?

Customers in Malaysia can complete an online consultation with a DoctorOnCall doctor, who decides whether a prescription is appropriate, or upload a valid prescription already issued by their own doctor.

Orders going to Singapore are dispatched from Malaysia as an international delivery, so you need to hold a valid prescription or doctor’s letter for the medicine. Check the consultation and prescription upload options shown at checkout for your delivery address before placing the order.

How long will delivery take?

Within Malaysia, standard delivery takes 3 to 5 working days. Same-day delivery is available in the Klang Valley for orders placed before 12pm; orders placed after 12pm arrive by the end of the next day.

Orders to Singapore are sent as international deliveries and take 5 to 9 working days. A lump-sum shipping and handling fee applies to every overseas delivery and is shown at checkout.

What payment methods can I use?

Customers in Malaysia can pay by FPX online banking, credit or debit card (Visa and Mastercard), and supported e-wallets including Touch ‘n Go eWallet, GrabPay and ShopeePay.

FPX and local e-wallets are tied to Malaysian bank and wallet accounts, so if your delivery address is in Singapore, use the payment options displayed at checkout for that address rather than assuming the same list applies.

Can Sifrol 0.125mg Tablet be delivered to Singapore?

Yes. DoctorOnCall ships to Singapore as an international order dispatched from Malaysia, arriving in 5 to 9 working days with a lump-sum shipping and handling fee.

Singapore’s Health Sciences Authority (HSA) allows personal imports of up to three months’ supply of a medicine for your own use or an immediate family member’s, as long as it contains no controlled drugs, psychotropic substances or prohibited items. Keep the product in its original labelled packaging and keep a copy of your prescription or doctor’s letter with it. Quantities above three months’ supply, and medicines containing controlled substances, require prior HSA approval.

Is Sifrol 0.125mg Tablet registered with the authorities?

Products listed on DoctorOnCall are registered with Malaysia’s Ministry of Health for supply in Malaysia, and each pack carries its MAL registration number.

An order delivered to Singapore arrives as a personal import of a Malaysia-registered product; HSA product registration is not required for personal-use quantities, but it is also not the same as a product registered for sale in Singapore. If you need a locally registered Singapore product, buy it from a pharmacy in Singapore.

Who do I contact if there is a problem with my order?

DoctorOnCall’s customer care team handles order, delivery and product queries through the contact channels on the site, including WhatsApp and the online help centre.

For deliveries to Singapore, allow more time before chasing an order than you would for a local Malaysian delivery, as the parcel passes through customs clearance and tracking updates can appear later in the journey.

Ingredients / Active Ingredients

  • Pramipexole 0.125mg (immediate-release)

Safety Advice

Pregnancy

Safe If Prescribed

This medicine should only be used during pregnancy if prescribed by a doctor after careful evaluation.

Breastfeeding

Limited Data

Limited data on excretion in breast milk. Consult a doctor before use.

Kidney

Use With Care

Use cautiously. Dose adjustment or monitoring may be required.

Liver

Generally Safe

Generally safe, but caution may be required in some patients.

Alcohol

Not Advisable

It is not advisable to consume alcohol while taking this medicine.

Driving

Use With Care

Use caution while driving until you know how this medicine affects you.

Medical Review

Written by:

Dr. Chong Zhan Pong

Doctor of Medicine (MD), International Medical University (IMU)

Reviewed by:

Dr. Mohd Izzat Amir Bin Awang

Doctor of Medicine (MD), University of Mansoura - Manchester

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