Stocrin 600mg Tablet
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Overview
Stocrin 600mg Tablet contains efavirenz 600mg, a non-nucleoside reverse transcriptase inhibitor (NNRTI) used as part of combination antiretroviral therapy (ART) for the treatment of HIV-1 infection in adults and children. It must always be used together with other antiretroviral medicines, never on its own, and treatment is managed by an HIV specialist.
Efavirenz works by binding directly to and blocking HIV reverse transcriptase, an enzyme the virus needs to convert its RNA into DNA inside human cells. By blocking this step, efavirenz prevents the virus from replicating and reduces the amount of virus in the blood.
How it Works
Efavirenz binds directly to HIV reverse transcriptase at a site distinct from where nucleoside analogues act, blocking the enzyme’s activity non-competitively. This prevents the virus from converting its RNA genome into DNA, stopping it from integrating into and replicating within human host cells.
Directions for Use
Take on an empty stomach, preferably at bedtime, as this may reduce central nervous system side effects such as dizziness and vivid dreams, and taking it with a high-fat meal can increase drug absorption to levels associated with more side effects. Take it at the same time every day and never stop or skip doses without consulting your HIV care team, as inconsistent dosing can lead to drug resistance.
Dosage
Efavirenz is prescribed and monitored by an HIV specialist as part of an individualised combination regimen. The dose and combination partners must never be adjusted without your specialist’s guidance, as HIV treatment requires very high, consistent adherence to avoid the virus developing resistance.
Shelf Life
Use this product before the expiry date stated on the packaging. Do not use the medicine if the expiry date has passed.
Storage Instructions
Store below 30°C in a dry place, away from direct sunlight and out of reach of children.
Side Effects
- Dizziness or trouble sleeping
- Headache or tiredness
- Skin rash
- Nausea or vomiting
- Changes in mood or mental health (e.g., depression, anxiety)
- Difficulty concentrating
Contraindications
- Known hypersensitivity to efavirenz
- Severe hepatic (liver) impairment
- Co-administration with certain medicines that interact seriously with efavirenz, as advised by your specialist
- Not recommended during pregnancy unless specifically advised by your HIV specialist due to a small increased risk of certain birth defects
Drug / Food Interactions
- Other antiretrovirals – efavirenz is always used in combination, and your specialist selects partner drugs carefully to avoid harmful interactions
- Rifampicin and certain other enzyme-inducing drugs – may require dose adjustment
- St John’s Wort and certain herbal supplements – can significantly reduce efavirenz levels and risk treatment failure
- Always inform your HIV specialist of every medicine, supplement, or herbal product you take, as many interactions with efavirenz are clinically significant
Quick Tips
- Take your regimen exactly as prescribed, every day, at the same time, to prevent the virus from developing resistance
- Take on an empty stomach, preferably at bedtime, to reduce central nervous system side effects
- Never stop or change your antiretroviral regimen without speaking to your HIV specialist first
- Attend all scheduled monitoring appointments, including blood tests to check liver function and viral load
Frequently Asked Questions
What is Stocrin used for?
It is an antiretroviral medicine used as part of a combination regimen to treat HIV-1 infection, always alongside other antiretroviral medicines and under specialist supervision.
How does this medicine work?
It blocks HIV reverse transcriptase, an enzyme the virus needs to convert its RNA into DNA, preventing the virus from replicating.
Can I take this medicine on its own?
No, efavirenz must always be combined with other antiretroviral medicines as part of a regimen prescribed by your HIV specialist – it is never used alone.
Why is bedtime dosing on an empty stomach recommended?
Taking it at bedtime on an empty stomach can reduce central nervous system side effects like dizziness and vivid dreams, and avoids increased absorption that can occur with a high-fat meal.
What are the common side effects?
Dizziness, drowsiness, vivid dreams, and skin rash are commonly reported, especially in the first few weeks of treatment.
Can this medicine be taken during pregnancy?
It is not generally recommended during pregnancy unless your HIV specialist specifically advises it, due to a small increased risk of certain birth defects – discuss this with your care team.
What happens if I miss doses of my HIV regimen?
Missing or inconsistently taking doses can allow the virus to develop resistance to treatment – take your regimen exactly as prescribed and contact your HIV care team if you miss doses.
Can I buy Stocrin 600mg Tablet from DoctorOnCall?
Yes, Stocrin 600mg Tablet is available through DoctorOnCall, a licensed online pharmacy serving our Malaysian and Singaporean customers. As this is a prescription medicine, you will need to complete an online consultation so a doctor can assess your suitability and issue a valid prescription before the order is processed. This ensures the medicine is appropriate for your condition and used under proper medical supervision, whether you are ordering from Malaysia or Singapore.
Is the medication provided by DoctorOnCall genuine and safe to use?
DoctorOnCall sources its medicines through appropriate licensed pharmacy supply channels for our Malaysian and Singaporean customers. All orders are dispensed and checked by a registered pharmacist before delivery. Always use Stocrin 600mg Tablet according to your doctor’s instructions and the information provided with the product.
What payment methods does DoctorOnCall accept?
We accept payment via Online Banking, Credit Card, and e-Wallets (Boost, GrabPay) for our Malaysian and Singaporean customers, so you can choose whichever method is most convenient for you at checkout.
Does DoctorOnCall provide an installment payment plan for Stocrin 600mg Tablet?
DoctorOnCall provides an installment payment plan for eligible Malaysian and Singaporean customers, where applicable. Available plans, eligibility, and terms can vary by market, so please contact DoctorOnCall Customer Service for the latest information on installment options for your order.
Is delivery free, and how much does shipping for Stocrin 600mg Tablet cost?
Delivery charges may vary for our Malaysian and Singaporean customers depending on your delivery location and the applicable order terms at the time of purchase. For the most accurate and up-to-date delivery fee information, please contact DoctorOnCall Customer Service before placing your order.
How long does delivery take for Stocrin 600mg Tablet?
Our Malaysian customers can generally expect delivery within 3-5 working days, while our Singaporean customers generally receive their orders within 5-7 working days. These are expected timeframes rather than guarantees, and actual delivery time may vary depending on your delivery location, order processing time, courier operations, and whether the order falls on a weekend or public holiday.
What is DoctorOnCall’s shipping, return, or cancellation policy for Stocrin 600mg Tablet?
Shipping, return, and cancellation terms may vary for our Malaysian and Singaporean customers depending on the product and your order details. Please refer to DoctorOnCall’s Shipping & Delivery Policy and Return, Refund & Exchange Policy, or contact Customer Service, for the specific terms that apply to your order.
Ingredients / Active Ingredients
- Efavirenz 600mg
Safety Advice
Pregnancy
This medicine should only be used during pregnancy if prescribed by a doctor after careful evaluation.
Breastfeeding
This medicine is not safe during breastfeeding and should be avoided.
Kidney
Generally safe, but caution may be required in some patients.
Liver
Use cautiously. Liver function monitoring may be required.
Alcohol
It is not advisable to consume alcohol while taking this medicine.
Driving
Use caution while driving until you know how this medicine affects you.
Medical Review
