Supirocin 2% Ointment

Supirocin 2% Ointment contains mupirocin, a topical antibiotic used to treat bacterial skin infections such as impetigo, infected cuts, infected insect bites, and infected eczema or dermatitis, particularly those caused by Staphylococcus aureus (including some antibiotic-resistant strains) and Streptococcus bacteria. It works directly at the site of infection, making it useful for localized, uncomplicated bacterial skin infections.

In Malaysia, Supirocin 2% Ointment usually requires a doctor’s prescription, as proper diagnosis is needed to confirm the infection is bacterial and suitable for topical antibiotic treatment, and to avoid overuse that could contribute to antibiotic resistance. An online consultation through DoctorOnCall allows a doctor to assess your skin condition and prescribe this ointment if appropriate.

Mupirocin works by inhibiting an enzyme called isoleucyl-tRNA synthetase inside susceptible bacteria, which blocks bacterial protein synthesis and stops the bacteria from growing and multiplying. This targeted mechanism makes it effective against many strains of Staphylococcus aureus and Streptococcus responsible for common skin infections.

Clean and dry the affected area before use, then apply a small amount of Supirocin 2% Ointment to the affected skin, usually covering it lightly with a gauze dressing if advised by your doctor. Wash your hands before and after application unless the hands themselves are being treated, and use the ointment for the full course prescribed, even if the skin appears to have healed.

The usual dose is a thin layer applied to the affected area 2 to 3 times daily for 5 to 10 days, or as directed by your doctor, depending on the severity and location of the infection. Do not use for longer than prescribed, and see your doctor if there is no improvement within 3 to 5 days of starting treatment.

Supirocin 2% Ointment should be used within the shelf life printed on the packaging when stored correctly and unopened; check the expiry date before use and discard any unused ointment after the course of treatment or once expired.

Store below 25°C in a cool, dry place away from direct sunlight, and keep the tube tightly closed when not in use. Keep out of reach and sight of children.

• Known hypersensitivity to mupirocin or polyethylene glycol (a component of the ointment base)
• Not for use in the eyes, nose, or on mucous membranes unless specifically directed by a doctor
• Caution with extensive use on open wounds or in patients with significant kidney impairment, due to the polyethylene glycol base
• Not intended for viral or fungal skin infections

• Minimal systemic drug interactions are expected because absorption through intact or minor broken skin is limited
• Avoid applying other topical creams or ointments to the same area at the same time without medical advice
• Inform your doctor if you are using other topical treatments for the same skin area

• Complete the full course of treatment even if the skin looks better after a few days
• Keep the affected area clean and covered if advised, to prevent spreading the infection
• Avoid sharing towels, clothing, or bedding while the infection is active, especially with impetigo
• Do not use Supirocin for longer than prescribed to help reduce the risk of antibiotic resistance
• See a doctor if the infection spreads, worsens, or does not improve within a few days

Supirocin 2% Ointment is intended for short courses of treatment for confirmed or clinically likely bacterial skin infections, and is not meant for long-term or repeated use without medical supervision, as overuse can contribute to antibiotic resistance. Good hygiene practices — such as keeping the area clean, avoiding scratching, and not sharing personal items — help prevent the infection from spreading to other parts of the body or to other people.